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| "id": "dae195c4-f43c-4ce0-b468-31b206564b5b", | |
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| "Suggestion de lecture à Pascal Pro : https://www.facebook.com/reel/6299386296830545 \n", | |
| "Article suggéré : https://academic.oup.com/ije/article/48/5/1519/5382278 \n", | |
| "Dossier sur le glyphosate : https://www.afis.org/Le-glyphosate-est-il-cancerogene" | |
| ] | |
| }, | |
| { | |
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| "execution_count": 1, | |
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| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T21:23:41.139030Z", | |
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| "import pandas as pd\n", | |
| "from io import StringIO" | |
| ] | |
| }, | |
| { | |
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| "id": "9c711a58-5bec-4eba-97e9-cbef43e7b193", | |
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| "source": [ | |
| "On récupère la table 2 en version HTML (en faisant un copier collé manuel du code source puisque le site est protégé contre le scraping)." | |
| ] | |
| }, | |
| { | |
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| "iopub.execute_input": "2024-04-16T21:23:43.419895Z", | |
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| "html_content = StringIO(\n", | |
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| " \n", | |
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| " <title>Pesticide use and risk of non-Hodgkin lymphoid malignancies in agricultural cohorts from France, Norway and the USA: a pooled analysis from the AGRICOH consortium | Oxford Academic</title>\n", | |
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| ".CtxtMenu_MenuComboBox { left:.1em; padding-bottom:.5em;}\n", | |
| ".CtxtMenu_MenuSlider { left: .1em;}\n", | |
| ".CtxtMenu_SliderValue { position:absolute; right:.1em; padding-top:.25em; color:#333333; font-size: .75em}\n", | |
| ".CtxtMenu_SliderBar { outline: none; background: #d3d3d3}\n", | |
| ".CtxtMenu_MenuLabel { padding: 1px 2em 3px 1.33em; font-style:italic}\n", | |
| ".CtxtMenu_MenuRule { border-top: 1px solid #DDDDDD; margin: 4px 3px;}\n", | |
| ".CtxtMenu_MenuDisabled { color:GrayText}\n", | |
| ".CtxtMenu_MenuActive { background-color: #606872; color: white;}\n", | |
| ".CtxtMenu_MenuDisabled:focus { background-color: #E8E8E8}\n", | |
| ".CtxtMenu_MenuLabel:focus { background-color: #E8E8E8}\n", | |
| ".CtxtMenu_ContextMenu:focus { outline:none}\n", | |
| ".CtxtMenu_ContextMenu .CtxtMenu_MenuItem:focus { outline:none}\n", | |
| ".CtxtMenu_SelectionMenu { position:relative; float:left; border-bottom: none; -webkit-box-shadow:none; -webkit-border-radius:0px; }\n", | |
| ".CtxtMenu_SelectionItem { padding-right: 1em;}\n", | |
| ".CtxtMenu_Selection { right: 40%; width:50%; }\n", | |
| ".CtxtMenu_SelectionBox { padding: 0em; max-height:20em; max-width: none; background-color:#FFFFFF;}\n", | |
| ".CtxtMenu_SelectionDivider { clear: both; border-top: 2px solid #000000;}\n", | |
| ".CtxtMenu_Menu .CtxtMenu_MenuClose { top:-10px; left:-10px}\n", | |
| "</style><style id=\"MJX-CHTML-styles\">\n", | |
| "mjx-container[jax=\"CHTML\"] {\n", | |
| " line-height: 0;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-container [space=\"1\"] {\n", | |
| " margin-left: .111em;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-container [space=\"2\"] {\n", | |
| " margin-left: .167em;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-container [space=\"3\"] {\n", | |
| " margin-left: .222em;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-container [space=\"4\"] {\n", | |
| " margin-left: .278em;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-container [space=\"5\"] {\n", | |
| " margin-left: .333em;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-container [rspace=\"1\"] {\n", | |
| " margin-right: .111em;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-container [rspace=\"2\"] {\n", | |
| " margin-right: .167em;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-container [rspace=\"3\"] {\n", | |
| " margin-right: .222em;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-container [rspace=\"4\"] {\n", | |
| " margin-right: .278em;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-container [rspace=\"5\"] {\n", | |
| " margin-right: .333em;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-container [size=\"s\"] {\n", | |
| " font-size: 70.7%;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-container [size=\"ss\"] {\n", | |
| " font-size: 50%;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-container [size=\"Tn\"] {\n", | |
| " font-size: 60%;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-container [size=\"sm\"] {\n", | |
| " font-size: 85%;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-container [size=\"lg\"] {\n", | |
| " font-size: 120%;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-container [size=\"Lg\"] {\n", | |
| " font-size: 144%;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-container [size=\"LG\"] {\n", | |
| " font-size: 173%;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-container [size=\"hg\"] {\n", | |
| " font-size: 207%;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-container [size=\"HG\"] {\n", | |
| " font-size: 249%;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-container [width=\"full\"] {\n", | |
| " width: 100%;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-box {\n", | |
| " display: inline-block;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-block {\n", | |
| " display: block;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-itable {\n", | |
| " display: inline-table;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-row {\n", | |
| " display: table-row;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-row > * {\n", | |
| " display: table-cell;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-mtext {\n", | |
| " display: inline-block;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-mstyle {\n", | |
| " display: inline-block;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-merror {\n", | |
| " display: inline-block;\n", | |
| " color: red;\n", | |
| " background-color: yellow;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-mphantom {\n", | |
| " visibility: hidden;\n", | |
| "}\n", | |
| "\n", | |
| "_::-webkit-full-page-media, _:future, :root mjx-container {\n", | |
| " will-change: opacity;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-assistive-mml {\n", | |
| " position: absolute !important;\n", | |
| " top: 0px;\n", | |
| " left: 0px;\n", | |
| " clip: rect(1px, 1px, 1px, 1px);\n", | |
| " padding: 1px 0px 0px 0px !important;\n", | |
| " border: 0px !important;\n", | |
| " display: block !important;\n", | |
| " width: auto !important;\n", | |
| " overflow: hidden !important;\n", | |
| " -webkit-touch-callout: none;\n", | |
| " -webkit-user-select: none;\n", | |
| " -khtml-user-select: none;\n", | |
| " -moz-user-select: none;\n", | |
| " -ms-user-select: none;\n", | |
| " user-select: none;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-assistive-mml[display=\"block\"] {\n", | |
| " width: 100% !important;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-c::before {\n", | |
| " display: block;\n", | |
| " width: 0;\n", | |
| "}\n", | |
| "\n", | |
| ".MJX-TEX {\n", | |
| " font-family: MJXZERO, MJXTEX;\n", | |
| "}\n", | |
| "\n", | |
| ".TEX-B {\n", | |
| " font-family: MJXZERO, MJXTEX-B;\n", | |
| "}\n", | |
| "\n", | |
| ".TEX-I {\n", | |
| " font-family: MJXZERO, MJXTEX-I;\n", | |
| "}\n", | |
| "\n", | |
| ".TEX-MI {\n", | |
| " font-family: MJXZERO, MJXTEX-MI;\n", | |
| "}\n", | |
| "\n", | |
| ".TEX-BI {\n", | |
| " font-family: MJXZERO, MJXTEX-BI;\n", | |
| "}\n", | |
| "\n", | |
| ".TEX-S1 {\n", | |
| " font-family: MJXZERO, MJXTEX-S1;\n", | |
| "}\n", | |
| "\n", | |
| ".TEX-S2 {\n", | |
| " font-family: MJXZERO, MJXTEX-S2;\n", | |
| "}\n", | |
| "\n", | |
| ".TEX-S3 {\n", | |
| " font-family: MJXZERO, MJXTEX-S3;\n", | |
| "}\n", | |
| "\n", | |
| ".TEX-S4 {\n", | |
| " font-family: MJXZERO, MJXTEX-S4;\n", | |
| "}\n", | |
| "\n", | |
| ".TEX-A {\n", | |
| " font-family: MJXZERO, MJXTEX-A;\n", | |
| "}\n", | |
| "\n", | |
| ".TEX-C {\n", | |
| " font-family: MJXZERO, MJXTEX-C;\n", | |
| "}\n", | |
| "\n", | |
| ".TEX-CB {\n", | |
| " font-family: MJXZERO, MJXTEX-CB;\n", | |
| "}\n", | |
| "\n", | |
| ".TEX-FR {\n", | |
| " font-family: MJXZERO, MJXTEX-FR;\n", | |
| "}\n", | |
| "\n", | |
| ".TEX-FRB {\n", | |
| " font-family: MJXZERO, MJXTEX-FRB;\n", | |
| "}\n", | |
| "\n", | |
| ".TEX-SS {\n", | |
| " font-family: MJXZERO, MJXTEX-SS;\n", | |
| "}\n", | |
| "\n", | |
| ".TEX-SSB {\n", | |
| " font-family: MJXZERO, MJXTEX-SSB;\n", | |
| "}\n", | |
| "\n", | |
| ".TEX-SSI {\n", | |
| " font-family: MJXZERO, MJXTEX-SSI;\n", | |
| "}\n", | |
| "\n", | |
| ".TEX-SC {\n", | |
| " font-family: MJXZERO, MJXTEX-SC;\n", | |
| "}\n", | |
| "\n", | |
| ".TEX-T {\n", | |
| " font-family: MJXZERO, MJXTEX-T;\n", | |
| "}\n", | |
| "\n", | |
| ".TEX-V {\n", | |
| " font-family: MJXZERO, MJXTEX-V;\n", | |
| "}\n", | |
| "\n", | |
| ".TEX-VB {\n", | |
| " font-family: MJXZERO, MJXTEX-VB;\n", | |
| "}\n", | |
| "\n", | |
| "mjx-stretchy-v mjx-c, mjx-stretchy-h mjx-c {\n", | |
| " font-family: MJXZERO, MJXTEX-S1, MJXTEX-S4, MJXTEX, MJXTEX-A ! important;\n", | |
| "}\n", | |
| "\n", | |
| "@font-face /* 0 */ {\n", | |
| " font-family: MJXZERO;\n", | |
| " src: url(\"https://cdn.jsdelivr.net/npm/mathjax@3/es5/output/chtml/fonts/woff-v2/MathJax_Zero.woff\") format(\"woff\");\n", | |
| "}\n", | |
| "\n", | |
| "@font-face /* 1 */ {\n", | |
| " font-family: MJXTEX;\n", | |
| " src: url(\"https://cdn.jsdelivr.net/npm/mathjax@3/es5/output/chtml/fonts/woff-v2/MathJax_Main-Regular.woff\") format(\"woff\");\n", | |
| "}\n", | |
| "\n", | |
| "@font-face /* 2 */ {\n", | |
| " font-family: MJXTEX-B;\n", | |
| " src: url(\"https://cdn.jsdelivr.net/npm/mathjax@3/es5/output/chtml/fonts/woff-v2/MathJax_Main-Bold.woff\") format(\"woff\");\n", | |
| "}\n", | |
| "\n", | |
| "@font-face /* 3 */ {\n", | |
| " font-family: MJXTEX-I;\n", | |
| " src: url(\"https://cdn.jsdelivr.net/npm/mathjax@3/es5/output/chtml/fonts/woff-v2/MathJax_Math-Italic.woff\") format(\"woff\");\n", | |
| "}\n", | |
| "\n", | |
| "@font-face /* 4 */ {\n", | |
| " font-family: MJXTEX-MI;\n", | |
| " src: url(\"https://cdn.jsdelivr.net/npm/mathjax@3/es5/output/chtml/fonts/woff-v2/MathJax_Main-Italic.woff\") format(\"woff\");\n", | |
| "}\n", | |
| "\n", | |
| "@font-face /* 5 */ {\n", | |
| " font-family: MJXTEX-BI;\n", | |
| " src: url(\"https://cdn.jsdelivr.net/npm/mathjax@3/es5/output/chtml/fonts/woff-v2/MathJax_Math-BoldItalic.woff\") format(\"woff\");\n", | |
| "}\n", | |
| "\n", | |
| "@font-face /* 6 */ {\n", | |
| " font-family: MJXTEX-S1;\n", | |
| " src: url(\"https://cdn.jsdelivr.net/npm/mathjax@3/es5/output/chtml/fonts/woff-v2/MathJax_Size1-Regular.woff\") format(\"woff\");\n", | |
| "}\n", | |
| "\n", | |
| "@font-face /* 7 */ {\n", | |
| " font-family: MJXTEX-S2;\n", | |
| " src: url(\"https://cdn.jsdelivr.net/npm/mathjax@3/es5/output/chtml/fonts/woff-v2/MathJax_Size2-Regular.woff\") format(\"woff\");\n", | |
| "}\n", | |
| "\n", | |
| "@font-face /* 8 */ {\n", | |
| " font-family: MJXTEX-S3;\n", | |
| " src: url(\"https://cdn.jsdelivr.net/npm/mathjax@3/es5/output/chtml/fonts/woff-v2/MathJax_Size3-Regular.woff\") format(\"woff\");\n", | |
| "}\n", | |
| "\n", | |
| "@font-face /* 9 */ {\n", | |
| " font-family: MJXTEX-S4;\n", | |
| " src: url(\"https://cdn.jsdelivr.net/npm/mathjax@3/es5/output/chtml/fonts/woff-v2/MathJax_Size4-Regular.woff\") format(\"woff\");\n", | |
| "}\n", | |
| "\n", | |
| "@font-face /* 10 */ {\n", | |
| " font-family: MJXTEX-A;\n", | |
| " src: url(\"https://cdn.jsdelivr.net/npm/mathjax@3/es5/output/chtml/fonts/woff-v2/MathJax_AMS-Regular.woff\") format(\"woff\");\n", | |
| "}\n", | |
| "\n", | |
| "@font-face /* 11 */ {\n", | |
| " font-family: MJXTEX-C;\n", | |
| " src: url(\"https://cdn.jsdelivr.net/npm/mathjax@3/es5/output/chtml/fonts/woff-v2/MathJax_Calligraphic-Regular.woff\") format(\"woff\");\n", | |
| "}\n", | |
| "\n", | |
| "@font-face /* 12 */ {\n", | |
| " font-family: MJXTEX-CB;\n", | |
| " src: url(\"https://cdn.jsdelivr.net/npm/mathjax@3/es5/output/chtml/fonts/woff-v2/MathJax_Calligraphic-Bold.woff\") format(\"woff\");\n", | |
| "}\n", | |
| "\n", | |
| "@font-face /* 13 */ {\n", | |
| " font-family: MJXTEX-FR;\n", | |
| " src: url(\"https://cdn.jsdelivr.net/npm/mathjax@3/es5/output/chtml/fonts/woff-v2/MathJax_Fraktur-Regular.woff\") format(\"woff\");\n", | |
| "}\n", | |
| "\n", | |
| "@font-face /* 14 */ {\n", | |
| " font-family: MJXTEX-FRB;\n", | |
| " src: url(\"https://cdn.jsdelivr.net/npm/mathjax@3/es5/output/chtml/fonts/woff-v2/MathJax_Fraktur-Bold.woff\") format(\"woff\");\n", | |
| "}\n", | |
| "\n", | |
| "@font-face /* 15 */ {\n", | |
| " font-family: MJXTEX-SS;\n", | |
| " src: url(\"https://cdn.jsdelivr.net/npm/mathjax@3/es5/output/chtml/fonts/woff-v2/MathJax_SansSerif-Regular.woff\") format(\"woff\");\n", | |
| "}\n", | |
| "\n", | |
| "@font-face /* 16 */ {\n", | |
| " font-family: MJXTEX-SSB;\n", | |
| " src: url(\"https://cdn.jsdelivr.net/npm/mathjax@3/es5/output/chtml/fonts/woff-v2/MathJax_SansSerif-Bold.woff\") format(\"woff\");\n", | |
| "}\n", | |
| "\n", | |
| "@font-face /* 17 */ {\n", | |
| " font-family: MJXTEX-SSI;\n", | |
| " src: url(\"https://cdn.jsdelivr.net/npm/mathjax@3/es5/output/chtml/fonts/woff-v2/MathJax_SansSerif-Italic.woff\") format(\"woff\");\n", | |
| "}\n", | |
| "\n", | |
| "@font-face /* 18 */ {\n", | |
| " font-family: MJXTEX-SC;\n", | |
| " src: url(\"https://cdn.jsdelivr.net/npm/mathjax@3/es5/output/chtml/fonts/woff-v2/MathJax_Script-Regular.woff\") format(\"woff\");\n", | |
| "}\n", | |
| "\n", | |
| "@font-face /* 19 */ {\n", | |
| " font-family: MJXTEX-T;\n", | |
| " src: url(\"https://cdn.jsdelivr.net/npm/mathjax@3/es5/output/chtml/fonts/woff-v2/MathJax_Typewriter-Regular.woff\") format(\"woff\");\n", | |
| "}\n", | |
| "\n", | |
| "@font-face /* 20 */ {\n", | |
| " font-family: MJXTEX-V;\n", | |
| " src: url(\"https://cdn.jsdelivr.net/npm/mathjax@3/es5/output/chtml/fonts/woff-v2/MathJax_Vector-Regular.woff\") format(\"woff\");\n", | |
| "}\n", | |
| "\n", | |
| "@font-face /* 21 */ {\n", | |
| " font-family: MJXTEX-VB;\n", | |
| " src: url(\"https://cdn.jsdelivr.net/npm/mathjax@3/es5/output/chtml/fonts/woff-v2/MathJax_Vector-Bold.woff\") format(\"woff\");\n", | |
| "}\n", | |
| "</style><link rel=\"stylesheet\" href=\"data:text/css,@import%20url%28%27https%3A//cdn.privado.ai/version/indexV1.css%27%29%3B\"><style>.swal2-popup.swal2-toast{box-sizing:border-box;grid-column:1/4 !important;grid-row:1/4 !important;grid-template-columns:min-content auto min-content;padding:1em;overflow-y:hidden;background:#fff;box-shadow:0 0 1px rgba(0,0,0,.075),0 1px 2px rgba(0,0,0,.075),1px 2px 4px rgba(0,0,0,.075),1px 3px 8px rgba(0,0,0,.075),2px 4px 16px rgba(0,0,0,.075);pointer-events:all}.swal2-popup.swal2-toast>*{grid-column:2}.swal2-popup.swal2-toast .swal2-title{margin:.5em 1em;padding:0;font-size:1em;text-align:initial}.swal2-popup.swal2-toast .swal2-loading{justify-content:center}.swal2-popup.swal2-toast .swal2-input{height:2em;margin:.5em;font-size:1em}.swal2-popup.swal2-toast .swal2-validation-message{font-size:1em}.swal2-popup.swal2-toast .swal2-footer{margin:.5em 0 0;padding:.5em 0 0;font-size:.8em}.swal2-popup.swal2-toast 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| " <div content-id=\"dyz017-T2\" class=\"table-modal table-full-width-wrap\"><div class=\"table-wrap standard-table\"><div class=\"table-wrap-title\" id=\"dyz017-T2\" data-id=\"dyz017-T2\"><span class=\"label title-label\" id=\"label-24986\">Table 2.</span><div class=\"caption caption-id-\" id=\"caption-24986\"><p class=\"chapter-para\">Ever use of 14 pesticide chemical groups and 33 active ingredients and meta-risk estimates, fully adjusted, of non-Hodgkin lymphoid malignancies diagnosed during follow-up in farmers and farm workers in three cohort studies from France, Norway and the USA</p></div> </div><div class=\"table-overflow\"><table role=\"table\" aria-labelledby=\"\n", | |
| " label-24986\" aria-describedby=\"\n", | |
| " caption-24986\"><thead><tr><th><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th colspan=\"5\">Non-Hodgkin lymphoid malignancies (NHL)<hr><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th colspan=\"5\">Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)<hr><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th colspan=\"5\">Diffuse large B-cell lymphoma (DLBCL)<hr><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th></tr><tr><th><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>N</em><sup>a</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>HR<sup>b</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>95% CI<span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>I<span class=\"xrefLink\" id=\"jumplink-dyz017-B2\"></span><sup>2</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>P</em><sup>e</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>N</em><sup>a</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>HR<sup>b</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>95% CI<span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>I<span class=\"xrefLink\" id=\"jumplink-dyz017-B2\"></span><sup>2</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>P</em><sup>e</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>N</em><sup>a</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>HR<sup>b</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>95% CI<span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>I<span class=\"xrefLink\" id=\"jumplink-dyz017-B2\"></span><sup>2</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>P</em><sup>e</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th></tr></thead><tbody><tr><td>OP Insecticides</td><td>1417</td><td>0.90</td><td>(0.75–1.09)</td><td>0%</td><td>0.56</td><td>318</td><td>1.03</td><td>(0.64–1.65)</td><td>0%</td><td>0.65</td><td>256</td><td>0.90</td><td>(0.58–1.39)</td><td>0%</td><td>0.71</td></tr><tr><td> Chlorpyrifos</td><td>453</td><td>0.99<sup>d</sup></td><td>(0.86–1.15)</td><td>0%</td><td>0.51</td><td>106</td><td>1.05<sup>d</sup></td><td>(0.77–1.42)</td><td>0%</td><td>0.84</td><td>86</td><td>0.99<sup>d</sup></td><td>(0.72–1.36)</td><td>0%</td><td>0.76</td></tr><tr><td> Dichlorvos</td><td>523</td><td>1.10</td><td>(0.95–1.27)</td><td>0%</td><td>0.72</td><td>116</td><td>1.07</td><td>(0.78–1.46)</td><td>0%</td><td>0.39</td><td>81</td><td>0.94</td><td>(0.67–1.32)</td><td>0%</td><td>0.84</td></tr><tr><td> Malathion</td><td>1208</td><td>0.98</td><td>(0.82–1.16)</td><td>0%</td><td>0.54</td><td>274</td><td>1.11</td><td>(0.76–1.64)</td><td>0%</td><td>0.89</td><td>209</td><td>0.84</td><td>(0.58–1.21)</td><td>0%</td><td>0.86</td></tr><tr><td> Parathion</td><td>995</td><td>0.95</td><td>(0.81–1.11)</td><td>0%</td><td>0.58</td><td>210</td><td>0.99</td><td>(0.70–1.40)</td><td>0%</td><td>0.93</td><td>162</td><td>0.91</td><td>(0.63–1.31)</td><td>0%</td><td>0.92</td></tr><tr><td> Terbufos</td><td>300</td><td>1.18<sup>d</sup></td><td>(1.00–1.39)</td><td>0%</td><td>0.53</td><td>76</td><td>1.28<sup>d</sup></td><td>(0.92–1.79)</td><td>0%</td><td>1.00</td><td>56</td><td>1.08<sup>d</sup></td><td>(0.74–1.57)</td><td>0%</td><td>0.57</td></tr><tr><td>Carbamate insecticides</td><td>1254</td><td>0.94</td><td>(0.81–1.08)</td><td>0%</td><td>0.97</td><td>283</td><td>1.06</td><td>(0.75–1.48)</td><td>0%</td><td>1.00</td><td>219</td><td>0.79</td><td>(0.56–1.11)</td><td>0%</td><td>0.77</td></tr><tr><td> Aldicarb</td><td>526</td><td>1.09</td><td>(0.95–1.26)</td><td>0%</td><td>0.67</td><td>116</td><td>1.16</td><td>(0.84–1.60)</td><td>0%</td><td>0.93</td><td>82</td><td>0.88</td><td>(0.63–1.24)</td><td>0%</td><td>0.91</td></tr><tr><td> Carbaryl</td><td>651</td><td>0.95</td><td>(0.83–1.10)</td><td>0%</td><td>0.52</td><td>148</td><td>0.97</td><td>(0.71–1.34)</td><td>0%</td><td>0.67</td><td>125</td><td>0.87</td><td>(0.64–1.19)</td><td>0%</td><td>0.96</td></tr><tr><td> Carbofuran</td><td>254</td><td>1.00<sup>d</sup></td><td>(0.84–1.20)</td><td>0%</td><td>0.59</td><td>63</td><td>1.08<sup>d</sup></td><td>(0.75–1.56)</td><td>0%</td><td>0.40</td><td>44</td><td>0.84<sup>d</sup></td><td>(0.55–1.27)</td><td>0%</td><td>0.92</td></tr><tr><td> Pirimicarb</td><td>796</td><td>0.90<sup>c</sup></td><td>(0.74–1.08)</td><td>0%</td><td>0.95</td><td>176</td><td>1.18<sup>c</sup></td><td>(0.77–1.82)</td><td>0%</td><td>0.51</td><td>123</td><td>0.71<sup>c</sup></td><td>(0.44–1.14)</td><td>0%</td><td>0.64</td></tr><tr><td>OC insecticides</td><td>1258</td><td>0.86</td><td>(0.74–0.99)</td><td>0%</td><td>0.77</td><td>288</td><td>1.08</td><td>(0.79–1.48)</td><td>0%</td><td>0.83</td><td>215</td><td>0.79</td><td>(0.52–1.20)</td><td>35%</td><td>0.21</td></tr><tr><td> DDT</td><td>976</td><td>0.92</td><td>(0.81–1.04)</td><td>0%</td><td>0.71</td><td>220</td><td>1.00</td><td>(0.77–1.31)</td><td>0%</td><td>0.75</td><td>165</td><td>0.85</td><td>(0.63–1.14)</td><td>0%</td><td>0.74</td></tr><tr><td> Lindane</td><td>953</td><td>0.89</td><td>(0.78–1.01)</td><td>0%</td><td>0.87</td><td>217</td><td>1.06</td><td>(0.79–1.41)</td><td>0%</td><td>0.60</td><td>160</td><td>0.94</td><td>(0.68–1.30)</td><td>0%</td><td>0.47</td></tr><tr><td>Pyrethroid insecticides</td><td>934</td><td>1.04</td><td>(0.90–1.19)</td><td>2%</td><td>0.36</td><td>211</td><td>1.29</td><td>(0.90–1.84)</td><td>15%</td><td>0.31</td><td>153</td><td>0.92</td><td>(0.66–1.28)</td><td>0%</td><td>0.72</td></tr><tr><td> Deltamethrin</td><td>627</td><td>1.04<sup>c</sup></td><td>(0.82–1.33)</td><td>59%</td><td>0.12</td><td>148</td><td>1.48<sup>c</sup></td><td>(1.06–2.07)</td><td>0%</td><td>0.35</td><td>99</td><td>0.96<sup>c</sup></td><td>(0.68–1.37)</td><td>0%</td><td>0.64</td></tr><tr><td> Esfenvalerate</td><td>549</td><td>1.15</td><td>(0.82–1.63)</td><td>69%</td><td>0.04</td><td>124</td><td>1.24<sup>c</sup></td><td>(0.79–1.94)</td><td>36%</td><td>0.21</td><td>89</td><td>1.03<sup>c</sup></td><td>(0.71–1.50)</td><td>0%</td><td>0.93</td></tr><tr><td> Permethrin</td><td>812</td><td>1.01</td><td>(0.87–1.19)</td><td>0%</td><td>0.97</td><td>182</td><td>1.30</td><td>(0.85–2.00)</td><td>25%</td><td>0.26</td><td>131</td><td>0.89</td><td>(0.61–1.29)</td><td>0%</td><td>0.96</td></tr><tr><td>(Phenyl) urea herbicides</td><td>979</td><td>1.03</td><td>(0.89–1.19)</td><td>0%</td><td>0.48</td><td>209</td><td>1.07</td><td>(0.75–1.51)</td><td>0%</td><td>0.97</td><td>156</td><td>0.86</td><td>(0.61–1.21)</td><td>0%</td><td>0.87</td></tr><tr><td> Isoproturon</td><td>453</td><td>1.03<sup>c</sup></td><td>(0.78–1.35)</td><td>55%</td><td>0.14</td><td>109</td><td>1.19<sup>c</sup></td><td>(0.79–1.78)</td><td>0%</td><td>0.54</td><td>73</td><td>0.82<sup>c</sup></td><td>(0.49–1.38)</td><td>21%</td><td>0.26</td></tr><tr><td> Linuron</td><td>961</td><td>1.06</td><td>(0.90–1.24)</td><td>0%</td><td>0.46</td><td>204</td><td>1.05</td><td>(0.73–1.49)</td><td>0%</td><td>0.92</td><td>155</td><td>0.94</td><td>(0.67–1.33)</td><td>0%</td><td>0.88</td></tr><tr><td>Dicamba</td><td>815</td><td>1.04</td><td>(0.90–1.19)</td><td>10%</td><td>0.33</td><td>180</td><td>1.05</td><td>(0.80–1.38)</td><td>0%</td><td>0.83</td><td>142</td><td>0.95</td><td>(0.70–1.29)</td><td>0%</td><td>0.44</td></tr><tr><td>Chloroacetanilides</td><td>735</td><td>1.00</td><td>(0.87–1.14)</td><td>0%</td><td>0.79</td><td>161</td><td>0.96</td><td>(0.68–1.35)</td><td>21%</td><td>0.28</td><td>145</td><td>1.08</td><td>(0.79–1.47)</td><td>0%</td><td>0.68</td></tr><tr><td> Alachlor</td><td>380</td><td>0.97<sup>d</sup></td><td>(0.81–1.15)</td><td>0%</td><td>0.45</td><td>85</td><td>0.92<sup>d</sup></td><td>(0.43–1.96)</td><td>68%</td><td>0.07</td><td>74</td><td>0.87<sup>d</sup></td><td>(0.60–1.24)</td><td>0%</td><td>0.87</td></tr><tr><td> Metolachlor</td><td>358</td><td>0.99<sup>d</sup></td><td>(0.84–1.17)</td><td>0%</td><td>0.57</td><td>88</td><td>1.02<sup>d</sup></td><td>(0.72–1.43)</td><td>0%</td><td>0.45</td><td>71</td><td>0.95<sup>d</sup></td><td>(0.64–1.42)</td><td>0%</td><td>0.86</td></tr><tr><td>Dinitroaniline herbicides</td><td>506</td><td>0.94<sup>d</sup></td><td>(0.78–1.12)</td><td>0%</td><td>0.34</td><td>126</td><td>1.07<sup>d</sup></td><td>(0.74–1.56)</td><td>0%</td><td>0.42</td><td>101</td><td>0.91<sup>d</sup></td><td>(0.62–1.31)</td><td>0%</td><td>0.88</td></tr><tr><td> Trifluralin</td><td>368</td><td>0.98<sup>d</sup></td><td>(0.72–1.33)</td><td>64%</td><td>0.10</td><td>90</td><td>0.92<sup>d</sup></td><td>(0.60–1.41)</td><td>15%</td><td>0.28</td><td>72</td><td>0.90<sup>d</sup></td><td>(0.62–1.32)</td><td>0%</td><td>0.66</td></tr><tr><td>Glyphosate</td><td>1131</td><td>0.95</td><td>(0.77–1.18)</td><td>57%</td><td>0.10</td><td>252</td><td>0.92</td><td>(0.69–1.24)</td><td>0%</td><td>0.38</td><td>221</td><td>1.36</td><td>(1.00–1.85)</td><td>0%</td><td>0.48</td></tr><tr><td>Phenoxy herbicides</td><td>1204</td><td>0.81</td><td>(0.67–0.98)</td><td>19%</td><td>0.29</td><td>272</td><td>0.89</td><td>(0.61–1.31)</td><td>0%</td><td>0.79</td><td>218</td><td>0.70</td><td>(0.32–1.52)</td><td>59%</td><td>0.09</td></tr><tr><td> 2, 4-D</td><td>1167</td><td>0.88</td><td>(0.75–1.04)</td><td>0%</td><td>0.87</td><td>262</td><td>0.92</td><td>(0.61–1.39)</td><td>19%</td><td>0.29</td><td>212</td><td>0.77</td><td>(0.46–1.30)</td><td>47%</td><td>0.15</td></tr><tr><td> MCPA</td><td>775</td><td>0.81<sup>c</sup></td><td>(0.53–1.23)</td><td>65%</td><td>0.09</td><td>163</td><td>0.98<sup>c</sup></td><td>(0.54–1.77)</td><td>0%</td><td>0.83</td><td>125</td><td></td><td></td><td></td><td></td></tr><tr><td> MCPP</td><td>776</td><td>0.94</td><td>(0.61–1.46)</td><td>65%</td><td>0.06</td><td>163</td><td>1.06<sup>c</sup></td><td>(0.57–1.98)</td><td>0%</td><td>0.63</td><td>124</td><td></td><td></td><td></td><td></td></tr><tr><td>Thiocarbamate herbicides</td><td>1015</td><td>0.93</td><td>(0.80–1.08)</td><td>0%</td><td>0.69</td><td>225</td><td>0.95</td><td>(0.63–1.45)</td><td>34%</td><td>0.22</td><td>171</td><td>0.88</td><td>(0.61–1.25)</td><td>0%</td><td>0.88</td></tr><tr><td> Butylate</td><td>265</td><td>1.01<sup>d</sup></td><td>(0.85–1.19)</td><td>0%</td><td>0.52</td><td>60</td><td>0.96<sup>d</sup></td><td>(0.50–1.85)</td><td>56%</td><td>0.13</td><td>48</td><td>0.89<sup>d</sup></td><td>(0.61–1.32)</td><td>0%</td><td>0.92</td></tr><tr><td> EPTC</td><td>606</td><td>1.04</td><td>(0.91–1.19)</td><td>0%</td><td>0.74</td><td>133</td><td>1.10</td><td>(0.76–1.60)</td><td>35%</td><td>0.21</td><td>101</td><td>1.12</td><td>(0.81–1.56)</td><td>0%</td><td>0.69</td></tr><tr><td>Triazine herbicides</td><td>1165</td><td>0.87</td><td>(0.74–1.02)</td><td>8%</td><td>0.34</td><td>269</td><td>0.85</td><td>(0.60–1.20)</td><td>0%</td><td>0.72</td><td>212</td><td>0.84</td><td>(0.60–1.18)</td><td>0%</td><td>0.40</td></tr><tr><td> Atrazine</td><td>546</td><td>0.97<sup>d</sup></td><td>(0.79–1.18)</td><td>0%</td><td>0.99</td><td>131</td><td>0.96<sup>d</sup></td><td>(0.62–1.49)</td><td>0%</td><td>0.35</td><td>109</td><td>0.88<sup>d</sup></td><td>(0.59–1.31)</td><td>0%</td><td>0.54</td></tr><tr><td> Simazine</td><td>303</td><td>0.92</td><td>(0.77–1.09)</td><td>0%</td><td>0.43</td><td>63</td><td>0.83</td><td>(0.53–1.31)</td><td>6%</td><td>0.35</td><td>54</td><td>0.91</td><td>(0.61–1.36)</td><td>0%</td><td>0.65</td></tr><tr><td>Triazinone herbicides</td><td>971</td><td>1.09</td><td>(0.85–1.40)</td><td>60%</td><td>0.08</td><td>215</td><td>1.22</td><td>(0.84–1.77)</td><td>21%</td><td>0.28</td><td>157</td><td>1.00</td><td>(0.73–1.36)</td><td>0%</td><td>0.67</td></tr><tr><td> Metribuzin</td><td>971</td><td>1.09</td><td>(0.85–1.40)</td><td>60%</td><td>0.08</td><td>215</td><td>1.22</td><td>(0.84–1.77)</td><td>21%</td><td>0.28</td><td>157</td><td>1.00</td><td>(0.73–1.36)</td><td>0%</td><td>0.67</td></tr><tr><td>Dithiocarbamate fungicides</td><td>961</td><td>0.96</td><td>(0.83–1.11)</td><td>0%</td><td>0.96</td><td>196</td><td>0.86</td><td>(0.62–1.19)</td><td>0%</td><td>0.72</td><td>157</td><td>0.93</td><td>(0.66–1.31)</td><td>0%</td><td>0.60</td></tr><tr><td> Mancozeb</td><td>932</td><td>0.94</td><td>(0.81–1.09)</td><td>0%</td><td>0.85</td><td>193</td><td>0.90</td><td>(0.64–1.26)</td><td>0%</td><td>0.66</td><td>149</td><td>0.87</td><td>(0.62–1.21)</td><td>0%</td><td>0.87</td></tr><tr><td> Thiram</td><td>264</td><td>0.89<sup>c</sup></td><td>(0.73–1.07)</td><td>0%</td><td>0.35</td><td>54</td><td>0.82<sup>c</sup></td><td>(0.40–1.66)</td><td>50%</td><td>0.16</td><td>42</td><td>0.79<sup>c</sup></td><td>(0.50–1.25)</td><td>0%</td><td>0.54</td></tr><tr><td>Phthalimide fungicides</td><td>921</td><td>1.10</td><td>(0.80–1.52)</td><td>57%</td><td>0.10</td><td>193</td><td>1.13</td><td>(0.74–1.72)</td><td>0%</td><td>0.47</td><td>144</td><td>0.98</td><td>(0.65–1.47)</td><td>0%</td><td>0.94</td></tr><tr><td> Captafol</td><td>800</td><td>1.12<sup>c</sup></td><td>(0.79–1.59)</td><td>69%</td><td>0.07</td><td>162</td><td>1.20<sup>c</sup></td><td>(0.71–2.03)</td><td>23%</td><td>0.25</td><td>121</td><td>0.93<sup>c</sup></td><td>(0.62–1.41)</td><td>0%</td><td>0.44</td></tr><tr><td> Captan</td><td>481</td><td>0.90</td><td>(0.74–1.10)</td><td>0%</td><td>0.45</td><td>107</td><td>0.92</td><td>(0.59–1.44)</td><td>13%</td><td>0.32</td><td>74</td><td>0.83</td><td>(0.52–1.33)</td><td>0%</td><td>0.68</td></tr><tr><td>Arsenicals</td><td>272</td><td><hr>0.97<sup>d</sup><hr></td><td><hr>(0.79–1.18)</td><td><hr>0%</td><td><hr>0.71</td><td>60</td><td>1.04<sup>d</sup></td><td>(0.66–1.63)</td><td>0%</td><td>0.49</td><td>52</td><td>1.19<sup>d</sup></td><td>(0.73–1.95)</td><td><hr>0%</td><td><hr>0.64</td></tr><tr><td colspan=\"16\"><hr></td></tr></tbody></table></div><div class=\"table-modal\"><table><thead><tr><th><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th colspan=\"5\">Non-Hodgkin lymphoid malignancies (NHL)<hr><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th colspan=\"5\">Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)<hr><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th colspan=\"5\">Diffuse large B-cell lymphoma (DLBCL)<hr><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th></tr><tr><th><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>N</em><sup>a</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>HR<sup>b</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>95% CI<span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>I<span class=\"xrefLink\" id=\"jumplink-dyz017-B2\"></span><sup>2</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>P</em><sup>e</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>N</em><sup>a</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>HR<sup>b</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>95% CI<span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>I<span class=\"xrefLink\" id=\"jumplink-dyz017-B2\"></span><sup>2</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>P</em><sup>e</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>N</em><sup>a</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>HR<sup>b</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>95% CI<span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>I<span class=\"xrefLink\" id=\"jumplink-dyz017-B2\"></span><sup>2</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>P</em><sup>e</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th></tr></thead><tbody><tr><td>OP Insecticides</td><td>1417</td><td>0.90</td><td>(0.75–1.09)</td><td>0%</td><td>0.56</td><td>318</td><td>1.03</td><td>(0.64–1.65)</td><td>0%</td><td>0.65</td><td>256</td><td>0.90</td><td>(0.58–1.39)</td><td>0%</td><td>0.71</td></tr><tr><td> Chlorpyrifos</td><td>453</td><td>0.99<sup>d</sup></td><td>(0.86–1.15)</td><td>0%</td><td>0.51</td><td>106</td><td>1.05<sup>d</sup></td><td>(0.77–1.42)</td><td>0%</td><td>0.84</td><td>86</td><td>0.99<sup>d</sup></td><td>(0.72–1.36)</td><td>0%</td><td>0.76</td></tr><tr><td> Dichlorvos</td><td>523</td><td>1.10</td><td>(0.95–1.27)</td><td>0%</td><td>0.72</td><td>116</td><td>1.07</td><td>(0.78–1.46)</td><td>0%</td><td>0.39</td><td>81</td><td>0.94</td><td>(0.67–1.32)</td><td>0%</td><td>0.84</td></tr><tr><td> Malathion</td><td>1208</td><td>0.98</td><td>(0.82–1.16)</td><td>0%</td><td>0.54</td><td>274</td><td>1.11</td><td>(0.76–1.64)</td><td>0%</td><td>0.89</td><td>209</td><td>0.84</td><td>(0.58–1.21)</td><td>0%</td><td>0.86</td></tr><tr><td> Parathion</td><td>995</td><td>0.95</td><td>(0.81–1.11)</td><td>0%</td><td>0.58</td><td>210</td><td>0.99</td><td>(0.70–1.40)</td><td>0%</td><td>0.93</td><td>162</td><td>0.91</td><td>(0.63–1.31)</td><td>0%</td><td>0.92</td></tr><tr><td> Terbufos</td><td>300</td><td>1.18<sup>d</sup></td><td>(1.00–1.39)</td><td>0%</td><td>0.53</td><td>76</td><td>1.28<sup>d</sup></td><td>(0.92–1.79)</td><td>0%</td><td>1.00</td><td>56</td><td>1.08<sup>d</sup></td><td>(0.74–1.57)</td><td>0%</td><td>0.57</td></tr><tr><td>Carbamate insecticides</td><td>1254</td><td>0.94</td><td>(0.81–1.08)</td><td>0%</td><td>0.97</td><td>283</td><td>1.06</td><td>(0.75–1.48)</td><td>0%</td><td>1.00</td><td>219</td><td>0.79</td><td>(0.56–1.11)</td><td>0%</td><td>0.77</td></tr><tr><td> Aldicarb</td><td>526</td><td>1.09</td><td>(0.95–1.26)</td><td>0%</td><td>0.67</td><td>116</td><td>1.16</td><td>(0.84–1.60)</td><td>0%</td><td>0.93</td><td>82</td><td>0.88</td><td>(0.63–1.24)</td><td>0%</td><td>0.91</td></tr><tr><td> Carbaryl</td><td>651</td><td>0.95</td><td>(0.83–1.10)</td><td>0%</td><td>0.52</td><td>148</td><td>0.97</td><td>(0.71–1.34)</td><td>0%</td><td>0.67</td><td>125</td><td>0.87</td><td>(0.64–1.19)</td><td>0%</td><td>0.96</td></tr><tr><td> Carbofuran</td><td>254</td><td>1.00<sup>d</sup></td><td>(0.84–1.20)</td><td>0%</td><td>0.59</td><td>63</td><td>1.08<sup>d</sup></td><td>(0.75–1.56)</td><td>0%</td><td>0.40</td><td>44</td><td>0.84<sup>d</sup></td><td>(0.55–1.27)</td><td>0%</td><td>0.92</td></tr><tr><td> Pirimicarb</td><td>796</td><td>0.90<sup>c</sup></td><td>(0.74–1.08)</td><td>0%</td><td>0.95</td><td>176</td><td>1.18<sup>c</sup></td><td>(0.77–1.82)</td><td>0%</td><td>0.51</td><td>123</td><td>0.71<sup>c</sup></td><td>(0.44–1.14)</td><td>0%</td><td>0.64</td></tr><tr><td>OC insecticides</td><td>1258</td><td>0.86</td><td>(0.74–0.99)</td><td>0%</td><td>0.77</td><td>288</td><td>1.08</td><td>(0.79–1.48)</td><td>0%</td><td>0.83</td><td>215</td><td>0.79</td><td>(0.52–1.20)</td><td>35%</td><td>0.21</td></tr><tr><td> DDT</td><td>976</td><td>0.92</td><td>(0.81–1.04)</td><td>0%</td><td>0.71</td><td>220</td><td>1.00</td><td>(0.77–1.31)</td><td>0%</td><td>0.75</td><td>165</td><td>0.85</td><td>(0.63–1.14)</td><td>0%</td><td>0.74</td></tr><tr><td> Lindane</td><td>953</td><td>0.89</td><td>(0.78–1.01)</td><td>0%</td><td>0.87</td><td>217</td><td>1.06</td><td>(0.79–1.41)</td><td>0%</td><td>0.60</td><td>160</td><td>0.94</td><td>(0.68–1.30)</td><td>0%</td><td>0.47</td></tr><tr><td>Pyrethroid insecticides</td><td>934</td><td>1.04</td><td>(0.90–1.19)</td><td>2%</td><td>0.36</td><td>211</td><td>1.29</td><td>(0.90–1.84)</td><td>15%</td><td>0.31</td><td>153</td><td>0.92</td><td>(0.66–1.28)</td><td>0%</td><td>0.72</td></tr><tr><td> Deltamethrin</td><td>627</td><td>1.04<sup>c</sup></td><td>(0.82–1.33)</td><td>59%</td><td>0.12</td><td>148</td><td>1.48<sup>c</sup></td><td>(1.06–2.07)</td><td>0%</td><td>0.35</td><td>99</td><td>0.96<sup>c</sup></td><td>(0.68–1.37)</td><td>0%</td><td>0.64</td></tr><tr><td> Esfenvalerate</td><td>549</td><td>1.15</td><td>(0.82–1.63)</td><td>69%</td><td>0.04</td><td>124</td><td>1.24<sup>c</sup></td><td>(0.79–1.94)</td><td>36%</td><td>0.21</td><td>89</td><td>1.03<sup>c</sup></td><td>(0.71–1.50)</td><td>0%</td><td>0.93</td></tr><tr><td> Permethrin</td><td>812</td><td>1.01</td><td>(0.87–1.19)</td><td>0%</td><td>0.97</td><td>182</td><td>1.30</td><td>(0.85–2.00)</td><td>25%</td><td>0.26</td><td>131</td><td>0.89</td><td>(0.61–1.29)</td><td>0%</td><td>0.96</td></tr><tr><td>(Phenyl) urea herbicides</td><td>979</td><td>1.03</td><td>(0.89–1.19)</td><td>0%</td><td>0.48</td><td>209</td><td>1.07</td><td>(0.75–1.51)</td><td>0%</td><td>0.97</td><td>156</td><td>0.86</td><td>(0.61–1.21)</td><td>0%</td><td>0.87</td></tr><tr><td> Isoproturon</td><td>453</td><td>1.03<sup>c</sup></td><td>(0.78–1.35)</td><td>55%</td><td>0.14</td><td>109</td><td>1.19<sup>c</sup></td><td>(0.79–1.78)</td><td>0%</td><td>0.54</td><td>73</td><td>0.82<sup>c</sup></td><td>(0.49–1.38)</td><td>21%</td><td>0.26</td></tr><tr><td> Linuron</td><td>961</td><td>1.06</td><td>(0.90–1.24)</td><td>0%</td><td>0.46</td><td>204</td><td>1.05</td><td>(0.73–1.49)</td><td>0%</td><td>0.92</td><td>155</td><td>0.94</td><td>(0.67–1.33)</td><td>0%</td><td>0.88</td></tr><tr><td>Dicamba</td><td>815</td><td>1.04</td><td>(0.90–1.19)</td><td>10%</td><td>0.33</td><td>180</td><td>1.05</td><td>(0.80–1.38)</td><td>0%</td><td>0.83</td><td>142</td><td>0.95</td><td>(0.70–1.29)</td><td>0%</td><td>0.44</td></tr><tr><td>Chloroacetanilides</td><td>735</td><td>1.00</td><td>(0.87–1.14)</td><td>0%</td><td>0.79</td><td>161</td><td>0.96</td><td>(0.68–1.35)</td><td>21%</td><td>0.28</td><td>145</td><td>1.08</td><td>(0.79–1.47)</td><td>0%</td><td>0.68</td></tr><tr><td> Alachlor</td><td>380</td><td>0.97<sup>d</sup></td><td>(0.81–1.15)</td><td>0%</td><td>0.45</td><td>85</td><td>0.92<sup>d</sup></td><td>(0.43–1.96)</td><td>68%</td><td>0.07</td><td>74</td><td>0.87<sup>d</sup></td><td>(0.60–1.24)</td><td>0%</td><td>0.87</td></tr><tr><td> Metolachlor</td><td>358</td><td>0.99<sup>d</sup></td><td>(0.84–1.17)</td><td>0%</td><td>0.57</td><td>88</td><td>1.02<sup>d</sup></td><td>(0.72–1.43)</td><td>0%</td><td>0.45</td><td>71</td><td>0.95<sup>d</sup></td><td>(0.64–1.42)</td><td>0%</td><td>0.86</td></tr><tr><td>Dinitroaniline herbicides</td><td>506</td><td>0.94<sup>d</sup></td><td>(0.78–1.12)</td><td>0%</td><td>0.34</td><td>126</td><td>1.07<sup>d</sup></td><td>(0.74–1.56)</td><td>0%</td><td>0.42</td><td>101</td><td>0.91<sup>d</sup></td><td>(0.62–1.31)</td><td>0%</td><td>0.88</td></tr><tr><td> Trifluralin</td><td>368</td><td>0.98<sup>d</sup></td><td>(0.72–1.33)</td><td>64%</td><td>0.10</td><td>90</td><td>0.92<sup>d</sup></td><td>(0.60–1.41)</td><td>15%</td><td>0.28</td><td>72</td><td>0.90<sup>d</sup></td><td>(0.62–1.32)</td><td>0%</td><td>0.66</td></tr><tr><td>Glyphosate</td><td>1131</td><td>0.95</td><td>(0.77–1.18)</td><td>57%</td><td>0.10</td><td>252</td><td>0.92</td><td>(0.69–1.24)</td><td>0%</td><td>0.38</td><td>221</td><td>1.36</td><td>(1.00–1.85)</td><td>0%</td><td>0.48</td></tr><tr><td>Phenoxy herbicides</td><td>1204</td><td>0.81</td><td>(0.67–0.98)</td><td>19%</td><td>0.29</td><td>272</td><td>0.89</td><td>(0.61–1.31)</td><td>0%</td><td>0.79</td><td>218</td><td>0.70</td><td>(0.32–1.52)</td><td>59%</td><td>0.09</td></tr><tr><td> 2, 4-D</td><td>1167</td><td>0.88</td><td>(0.75–1.04)</td><td>0%</td><td>0.87</td><td>262</td><td>0.92</td><td>(0.61–1.39)</td><td>19%</td><td>0.29</td><td>212</td><td>0.77</td><td>(0.46–1.30)</td><td>47%</td><td>0.15</td></tr><tr><td> MCPA</td><td>775</td><td>0.81<sup>c</sup></td><td>(0.53–1.23)</td><td>65%</td><td>0.09</td><td>163</td><td>0.98<sup>c</sup></td><td>(0.54–1.77)</td><td>0%</td><td>0.83</td><td>125</td><td></td><td></td><td></td><td></td></tr><tr><td> MCPP</td><td>776</td><td>0.94</td><td>(0.61–1.46)</td><td>65%</td><td>0.06</td><td>163</td><td>1.06<sup>c</sup></td><td>(0.57–1.98)</td><td>0%</td><td>0.63</td><td>124</td><td></td><td></td><td></td><td></td></tr><tr><td>Thiocarbamate herbicides</td><td>1015</td><td>0.93</td><td>(0.80–1.08)</td><td>0%</td><td>0.69</td><td>225</td><td>0.95</td><td>(0.63–1.45)</td><td>34%</td><td>0.22</td><td>171</td><td>0.88</td><td>(0.61–1.25)</td><td>0%</td><td>0.88</td></tr><tr><td> Butylate</td><td>265</td><td>1.01<sup>d</sup></td><td>(0.85–1.19)</td><td>0%</td><td>0.52</td><td>60</td><td>0.96<sup>d</sup></td><td>(0.50–1.85)</td><td>56%</td><td>0.13</td><td>48</td><td>0.89<sup>d</sup></td><td>(0.61–1.32)</td><td>0%</td><td>0.92</td></tr><tr><td> EPTC</td><td>606</td><td>1.04</td><td>(0.91–1.19)</td><td>0%</td><td>0.74</td><td>133</td><td>1.10</td><td>(0.76–1.60)</td><td>35%</td><td>0.21</td><td>101</td><td>1.12</td><td>(0.81–1.56)</td><td>0%</td><td>0.69</td></tr><tr><td>Triazine herbicides</td><td>1165</td><td>0.87</td><td>(0.74–1.02)</td><td>8%</td><td>0.34</td><td>269</td><td>0.85</td><td>(0.60–1.20)</td><td>0%</td><td>0.72</td><td>212</td><td>0.84</td><td>(0.60–1.18)</td><td>0%</td><td>0.40</td></tr><tr><td> Atrazine</td><td>546</td><td>0.97<sup>d</sup></td><td>(0.79–1.18)</td><td>0%</td><td>0.99</td><td>131</td><td>0.96<sup>d</sup></td><td>(0.62–1.49)</td><td>0%</td><td>0.35</td><td>109</td><td>0.88<sup>d</sup></td><td>(0.59–1.31)</td><td>0%</td><td>0.54</td></tr><tr><td> Simazine</td><td>303</td><td>0.92</td><td>(0.77–1.09)</td><td>0%</td><td>0.43</td><td>63</td><td>0.83</td><td>(0.53–1.31)</td><td>6%</td><td>0.35</td><td>54</td><td>0.91</td><td>(0.61–1.36)</td><td>0%</td><td>0.65</td></tr><tr><td>Triazinone herbicides</td><td>971</td><td>1.09</td><td>(0.85–1.40)</td><td>60%</td><td>0.08</td><td>215</td><td>1.22</td><td>(0.84–1.77)</td><td>21%</td><td>0.28</td><td>157</td><td>1.00</td><td>(0.73–1.36)</td><td>0%</td><td>0.67</td></tr><tr><td> Metribuzin</td><td>971</td><td>1.09</td><td>(0.85–1.40)</td><td>60%</td><td>0.08</td><td>215</td><td>1.22</td><td>(0.84–1.77)</td><td>21%</td><td>0.28</td><td>157</td><td>1.00</td><td>(0.73–1.36)</td><td>0%</td><td>0.67</td></tr><tr><td>Dithiocarbamate fungicides</td><td>961</td><td>0.96</td><td>(0.83–1.11)</td><td>0%</td><td>0.96</td><td>196</td><td>0.86</td><td>(0.62–1.19)</td><td>0%</td><td>0.72</td><td>157</td><td>0.93</td><td>(0.66–1.31)</td><td>0%</td><td>0.60</td></tr><tr><td> Mancozeb</td><td>932</td><td>0.94</td><td>(0.81–1.09)</td><td>0%</td><td>0.85</td><td>193</td><td>0.90</td><td>(0.64–1.26)</td><td>0%</td><td>0.66</td><td>149</td><td>0.87</td><td>(0.62–1.21)</td><td>0%</td><td>0.87</td></tr><tr><td> Thiram</td><td>264</td><td>0.89<sup>c</sup></td><td>(0.73–1.07)</td><td>0%</td><td>0.35</td><td>54</td><td>0.82<sup>c</sup></td><td>(0.40–1.66)</td><td>50%</td><td>0.16</td><td>42</td><td>0.79<sup>c</sup></td><td>(0.50–1.25)</td><td>0%</td><td>0.54</td></tr><tr><td>Phthalimide fungicides</td><td>921</td><td>1.10</td><td>(0.80–1.52)</td><td>57%</td><td>0.10</td><td>193</td><td>1.13</td><td>(0.74–1.72)</td><td>0%</td><td>0.47</td><td>144</td><td>0.98</td><td>(0.65–1.47)</td><td>0%</td><td>0.94</td></tr><tr><td> Captafol</td><td>800</td><td>1.12<sup>c</sup></td><td>(0.79–1.59)</td><td>69%</td><td>0.07</td><td>162</td><td>1.20<sup>c</sup></td><td>(0.71–2.03)</td><td>23%</td><td>0.25</td><td>121</td><td>0.93<sup>c</sup></td><td>(0.62–1.41)</td><td>0%</td><td>0.44</td></tr><tr><td> Captan</td><td>481</td><td>0.90</td><td>(0.74–1.10)</td><td>0%</td><td>0.45</td><td>107</td><td>0.92</td><td>(0.59–1.44)</td><td>13%</td><td>0.32</td><td>74</td><td>0.83</td><td>(0.52–1.33)</td><td>0%</td><td>0.68</td></tr><tr><td>Arsenicals</td><td>272</td><td><hr>0.97<sup>d</sup><hr></td><td><hr>(0.79–1.18)</td><td><hr>0%</td><td><hr>0.71</td><td>60</td><td>1.04<sup>d</sup></td><td>(0.66–1.63)</td><td>0%</td><td>0.49</td><td>52</td><td>1.19<sup>d</sup></td><td>(0.73–1.95)</td><td><hr>0%</td><td><hr>0.64</td></tr><tr><td colspan=\"16\"><hr></td></tr></tbody></table></div><div class=\"table-overflow\"><table role=\"table\" aria-labelledby=\"\n", | |
| " label-24986\" aria-describedby=\"\n", | |
| " caption-24986\"><thead><tr><th><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th colspan=\"5\"><hr>Follicular lymphoma (FL)<hr><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th colspan=\"5\">Multiple myeloma/plasma-cell leukaemia (MM)<hr><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th></tr><tr><th><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>N</em><span class=\"xrefLink\" id=\"jumplink-tblfn7\"></span><a href=\"javascript:;\" reveal-id=\"tblfn7\" data-open=\"tblfn7\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>a</sup></a><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>HR<span class=\"xrefLink\" id=\"jumplink-tblfn8\"></span><a href=\"javascript:;\" reveal-id=\"tblfn8\" data-open=\"tblfn8\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>b</sup></a><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>95% CI<span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>I<span class=\"xrefLink\" id=\"jumplink-dyz017-B2\"></span><sup>2</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>P</em><span class=\"xrefLink\" id=\"jumplink-tblfn12\"></span><a href=\"javascript:;\" reveal-id=\"tblfn12\" data-open=\"tblfn12\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>e</sup></a><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>N</em><span class=\"xrefLink\" id=\"jumplink-tblfn7\"></span><a href=\"javascript:;\" reveal-id=\"tblfn7\" data-open=\"tblfn7\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>a</sup></a><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>HR<span class=\"xrefLink\" id=\"jumplink-tblfn8\"></span><a href=\"javascript:;\" reveal-id=\"tblfn8\" data-open=\"tblfn8\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>b</sup></a><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>95% CI<span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>I<span class=\"xrefLink\" id=\"jumplink-dyz017-B2\"></span><sup>2</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>P</em><span class=\"xrefLink\" id=\"jumplink-tblfn12\"></span><a href=\"javascript:;\" reveal-id=\"tblfn12\" data-open=\"tblfn12\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>e</sup></a><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th></tr></thead><tbody><tr><td>OP insecticides</td><td>131</td><td>0.78</td><td>(0.34–1.76)</td><td>2%</td><td>0.36</td><td>313</td><td>0.85</td><td>(0.56–1.29)</td><td>0%</td><td>0.83</td></tr><tr><td> Chlorpyrifos</td><td>46</td><td>1.08<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.68–1.70)</td><td>0%</td><td>0.58</td><td>97</td><td>0.93<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.66–1.32)</td><td>0%</td><td>0.73</td></tr><tr><td> Dichlorvos</td><td>40</td><td>1.10</td><td>(0.69–1.76)</td><td>0%</td><td>0.95</td><td>111</td><td>0.98</td><td>(0.70–1.37)</td><td>22%</td><td>0.28</td></tr><tr><td> Malathion</td><td>114</td><td>1.18</td><td>(0.66–2.10)</td><td>0%</td><td>0.64</td><td>269</td><td>0.95</td><td>(0.67–1.36)</td><td>0%</td><td>0.69</td></tr><tr><td> Parathion</td><td>83</td><td>1.24</td><td>(0.72–2.15)</td><td>0%</td><td>0.44</td><td>230</td><td>0.84</td><td>(0.57–1.24)</td><td>18%</td><td>0.30</td></tr><tr><td> Terbufos</td><td>35</td><td>1.33<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.80–2.20)</td><td>0%</td><td>0.70</td><td>55</td><td>1.01<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.69–1.49)</td><td>0%</td><td>0.64</td></tr><tr><td>Carbamate insecticides</td><td>115</td><td>1.03</td><td>(0.63–1.68)</td><td>0%</td><td>0.47</td><td>290</td><td>1.25</td><td>(0.89–1.75)</td><td>9%</td><td>0.33</td></tr><tr><td> Aldicarb</td><td>38</td><td>0.94</td><td>(0.56–1.56)</td><td>0%</td><td>0.79</td><td>113</td><td>0.91</td><td>(0.68–1.22)</td><td>0%</td><td>0.58</td></tr><tr><td> Carbaryl</td><td>67</td><td>1.27<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.66–2.43)</td><td>27%</td><td>0.24</td><td>152</td><td>1.11</td><td>(0.71–1.74)</td><td>47%</td><td>0.15</td></tr><tr><td> Carbofuran</td><td>26</td><td>0.91<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.52–1.59)</td><td>0%</td><td>0.94</td><td>57</td><td>1.21<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.83–1.78)</td><td>0%</td><td>0.70</td></tr><tr><td> Pirimicarb</td><td>58</td><td>0.84<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.41–1.71)</td><td>0%</td><td>0.96</td><td>185</td><td>1.01<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.70–1.46)</td><td>0%</td><td>0.68</td></tr><tr><td>OC insecticides</td><td>114</td><td>0.87</td><td>(0.54–1.40)</td><td>0%</td><td>0.82</td><td>290</td><td>1.03</td><td>(0.76–1.40)</td><td>0%</td><td>0.97</td></tr><tr><td> DDT</td><td>79</td><td>0.78</td><td>(0.45–1.37)</td><td>38%</td><td>0.20</td><td>230</td><td>0.96</td><td>(0.74–1.25)</td><td>0%</td><td>0.86</td></tr><tr><td> Lindane</td><td>78</td><td>0.92</td><td>(0.61–1.38)</td><td>0%</td><td>0.57</td><td>216</td><td>0.97</td><td>(0.74–1.28)</td><td>0%</td><td>0.89</td></tr><tr><td>Pyrethroid insecticides</td><td>81</td><td>1.16</td><td>(0.75–1.79)</td><td>0%</td><td>0.87</td><td>210</td><td>1.07</td><td>(0.79–1.46)</td><td>0%</td><td>0.72</td></tr><tr><td> Deltamethrin</td><td>46</td><td>1.09<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.64–1.87)</td><td>0%</td><td>0.77</td><td>135</td><td>0.93<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.69–1.24)</td><td>0%</td><td>0.97</td></tr><tr><td> Esfenvalerate</td><td>41</td><td>1.04<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.61–1.75)</td><td>0%</td><td>0.44</td><td>120</td><td>1.65</td><td>(0.61–4.41)</td><td>89%</td><td>0.00</td></tr><tr><td> Permethrin</td><td>60</td><td>0.79</td><td>(0.42–1.50)</td><td>26%</td><td>0.26</td><td>187</td><td>1.18</td><td>(0.86–1.63)</td><td>0%</td><td>0.61</td></tr><tr><td>(Phenyl) urea herbicides</td><td>81</td><td>1.09</td><td>(0.65–1.82)</td><td>0%</td><td>0.84</td><td>227</td><td>1.08</td><td>(0.79–1.47)</td><td>0%</td><td>0.65</td></tr><tr><td> Isoproturon</td><td>28</td><td>0.70<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.36–1.36)</td><td>0%</td><td>0.90</td><td>100</td><td>1.04<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.72–1.52)</td><td>0%</td><td>0.78</td></tr><tr><td> Linuron</td><td>79</td><td>1.11</td><td>(0.66–1.87)</td><td>0%</td><td>0.76</td><td>224</td><td>1.13</td><td>(0.81–1.57)</td><td>0%</td><td>0.78</td></tr><tr><td>Dicamba</td><td>73</td><td>0.81</td><td>(0.53–1.23)</td><td>0%</td><td>0.63</td><td>179</td><td>1.21</td><td>(0.93–1.59)</td><td>0%</td><td>0.92</td></tr><tr><td>Chloroacetanilides</td><td>78</td><td>1.00</td><td>(0.63–1.58)</td><td>0%</td><td>0.92</td><td>147</td><td>0.94</td><td>(0.71–1.25)</td><td>0%</td><td>0.88</td></tr><tr><td> Alachlor</td><td>43</td><td>0.86<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.47–1.56)</td><td>0%</td><td>0.96</td><td>78</td><td>1.06<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.73–1.54)</td><td>0%</td><td>0.94</td></tr><tr><td> Metolachlor</td><td>43</td><td>1.05<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.59–1.86)</td><td>0%</td><td>0.90</td><td>71</td><td>1.05<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.71–1.53)</td><td>0%</td><td>0.71</td></tr><tr><td>Dinitroaniline herbicides</td><td>57</td><td>0.99<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.56–1.74)</td><td>0%</td><td>0.71</td><td>95</td><td>0.82<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.42–1.61)</td><td>69%</td><td>0.07</td></tr><tr><td> Trifluralin</td><td>39</td><td>0.80<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.47–1.35)</td><td>0%</td><td>0.66</td><td>70</td><td>0.89<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.60–1.32)</td><td>0%</td><td>0.44</td></tr><tr><td>Glyphosate</td><td>105</td><td>0.79</td><td>(0.52–1.21)</td><td>0%</td><td>0.56</td><td>240</td><td>0.87</td><td>(0.66–1.15)</td><td>0%</td><td>0.95</td></tr><tr><td>Phenoxy herbicides</td><td>115</td><td>1.02</td><td>(0.60–1.75)</td><td>0%</td><td>0.95</td><td>257</td><td>0.77</td><td>(0.49–1.22)</td><td>43%</td><td>0.18</td></tr><tr><td> 2, 4-D</td><td>113</td><td>1.14</td><td>(0.67–1.96)</td><td>0%</td><td>0.91</td><td>250</td><td>0.90</td><td>(0.65–1.26)</td><td>0%</td><td>0.53</td></tr><tr><td> MCPA</td><td>60</td><td>1.21<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.53–2.80)</td><td>6%</td><td>0.30</td><td>174</td><td>0.69<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.29–1.64)</td><td>64%</td><td>0.10</td></tr><tr><td> MCPP</td><td>59</td><td>0.96<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.25–3.61)</td><td>58%</td><td>0.13</td><td>175</td><td>0.82<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.25–2.67)</td><td>82%</td><td>0.02</td></tr><tr><td>Thiocarbamate herbicides</td><td>88</td><td>0.81</td><td>(0.52–1.26)</td><td>0%</td><td>0.68</td><td>225</td><td>0.99</td><td>(0.73–1.34)</td><td>0%</td><td>0.80</td></tr><tr><td> Butylate</td><td>31</td><td>1.06<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.63–1.77)</td><td>0%</td><td>0.94</td><td>54</td><td>1.04<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.70–1.53)</td><td>0%</td><td>0.69</td></tr><tr><td> EPTC</td><td>49</td><td>0.86</td><td>(0.42–1.73)</td><td>51%</td><td>0.13</td><td>138</td><td>1.19</td><td>(0.90–1.59)</td><td>0%</td><td>0.87</td></tr><tr><td>Triazine herbicides</td><td>115</td><td>1.45</td><td>(0.62–3.39)</td><td>56%</td><td>0.10</td><td>246</td><td>0.82</td><td>(0.50–1.35)</td><td>56%</td><td>0.10</td></tr><tr><td> Atrazine</td><td>65</td><td>1.28<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.69–2.38)</td><td>0%</td><td>0.79</td><td>108</td><td>0.98<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.62–1.55)</td><td>0%</td><td>0.54</td></tr><tr><td> Simazine</td><td>23</td><td>0.91</td><td>(0.48–1.70)</td><td>0%</td><td>0.88</td><td>66</td><td>0.83</td><td>(0.52–1.32)</td><td>35%</td><td>0.22</td></tr><tr><td>Triazinone herbicides</td><td>86</td><td>0.85</td><td>(0.54–1.36)</td><td>0%</td><td>0.41</td><td>221</td><td>1.20</td><td>(0.73–1.97)</td><td>51%</td><td>0.13</td></tr><tr><td> Metribuzin</td><td>86</td><td>0.86</td><td>(0.54–1.36)</td><td>0%</td><td>0.41</td><td>221</td><td>1.20</td><td>(0.74–1.97)</td><td>51%</td><td>0.13</td></tr><tr><td>Dithiocarbamate fungicides</td><td>75</td><td>0.88</td><td>(0.52–1.49)</td><td>0%</td><td>0.98</td><td>229</td><td>1.11</td><td>(0.80–1.52)</td><td>0%</td><td>0.74</td></tr><tr><td> Mancozeb</td><td>71</td><td>0.80</td><td>(0.46–1.39)</td><td>0%</td><td>0.90</td><td>222</td><td>1.07</td><td>(0.78–1.48)</td><td>0%</td><td>0.64</td></tr><tr><td> Thiram</td><td>17</td><td>0.84<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.40–1.79)</td><td>0%</td><td>0.72</td><td>58</td><td>0.80<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.40–1.61)</td><td>60%</td><td>0.12</td></tr><tr><td>Phthalimide fungicides</td><td>71</td><td>0.73<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.37–1.44)</td><td>0%</td><td>0.84</td><td>216</td><td>1.05</td><td>(0.71–1.54)</td><td>0%</td><td>0.81</td></tr><tr><td> Captafol</td><td>62</td><td>1.11<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.51–2.42)</td><td>10%</td><td>0.29</td><td>192</td><td>1.13<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.76–1.68)</td><td>0%</td><td>0.45</td></tr><tr><td> Captan</td><td>36</td><td>0.90</td><td>(0.47–1.72)</td><td>0%</td><td>0.59</td><td>97</td><td>0.73</td><td>(0.39–1.37)</td><td>48%</td><td>0.15</td></tr><tr><td>Arsenicals</td><td>17</td><td></td><td></td><td></td><td></td><td>65</td><td>0.91<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.59–1.40)</td><td>0%</td><td>0.84</td></tr><tr><td colspan=\"11\"><hr></td></tr></tbody></table></div><div class=\"table-modal\"><table><thead><tr><th><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th colspan=\"5\"><hr>Follicular lymphoma (FL)<hr><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th colspan=\"5\">Multiple myeloma/plasma-cell leukaemia (MM)<hr><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th></tr><tr><th><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>N</em><span class=\"xrefLink\" id=\"jumplink-tblfn7\"></span><a href=\"javascript:;\" reveal-id=\"tblfn7\" data-open=\"tblfn7\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>a</sup></a><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>HR<span class=\"xrefLink\" id=\"jumplink-tblfn8\"></span><a href=\"javascript:;\" reveal-id=\"tblfn8\" data-open=\"tblfn8\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>b</sup></a><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>95% CI<span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>I<span class=\"xrefLink\" id=\"jumplink-dyz017-B2\"></span><sup>2</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>P</em><span class=\"xrefLink\" id=\"jumplink-tblfn12\"></span><a href=\"javascript:;\" reveal-id=\"tblfn12\" data-open=\"tblfn12\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>e</sup></a><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>N</em><span class=\"xrefLink\" id=\"jumplink-tblfn7\"></span><a href=\"javascript:;\" reveal-id=\"tblfn7\" data-open=\"tblfn7\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>a</sup></a><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>HR<span class=\"xrefLink\" id=\"jumplink-tblfn8\"></span><a href=\"javascript:;\" reveal-id=\"tblfn8\" data-open=\"tblfn8\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>b</sup></a><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>95% CI<span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>I<span class=\"xrefLink\" id=\"jumplink-dyz017-B2\"></span><sup>2</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>P</em><span class=\"xrefLink\" id=\"jumplink-tblfn12\"></span><a href=\"javascript:;\" reveal-id=\"tblfn12\" data-open=\"tblfn12\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>e</sup></a><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th></tr></thead><tbody><tr><td>OP insecticides</td><td>131</td><td>0.78</td><td>(0.34–1.76)</td><td>2%</td><td>0.36</td><td>313</td><td>0.85</td><td>(0.56–1.29)</td><td>0%</td><td>0.83</td></tr><tr><td> Chlorpyrifos</td><td>46</td><td>1.08<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.68–1.70)</td><td>0%</td><td>0.58</td><td>97</td><td>0.93<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.66–1.32)</td><td>0%</td><td>0.73</td></tr><tr><td> Dichlorvos</td><td>40</td><td>1.10</td><td>(0.69–1.76)</td><td>0%</td><td>0.95</td><td>111</td><td>0.98</td><td>(0.70–1.37)</td><td>22%</td><td>0.28</td></tr><tr><td> Malathion</td><td>114</td><td>1.18</td><td>(0.66–2.10)</td><td>0%</td><td>0.64</td><td>269</td><td>0.95</td><td>(0.67–1.36)</td><td>0%</td><td>0.69</td></tr><tr><td> Parathion</td><td>83</td><td>1.24</td><td>(0.72–2.15)</td><td>0%</td><td>0.44</td><td>230</td><td>0.84</td><td>(0.57–1.24)</td><td>18%</td><td>0.30</td></tr><tr><td> Terbufos</td><td>35</td><td>1.33<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.80–2.20)</td><td>0%</td><td>0.70</td><td>55</td><td>1.01<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.69–1.49)</td><td>0%</td><td>0.64</td></tr><tr><td>Carbamate insecticides</td><td>115</td><td>1.03</td><td>(0.63–1.68)</td><td>0%</td><td>0.47</td><td>290</td><td>1.25</td><td>(0.89–1.75)</td><td>9%</td><td>0.33</td></tr><tr><td> Aldicarb</td><td>38</td><td>0.94</td><td>(0.56–1.56)</td><td>0%</td><td>0.79</td><td>113</td><td>0.91</td><td>(0.68–1.22)</td><td>0%</td><td>0.58</td></tr><tr><td> Carbaryl</td><td>67</td><td>1.27<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.66–2.43)</td><td>27%</td><td>0.24</td><td>152</td><td>1.11</td><td>(0.71–1.74)</td><td>47%</td><td>0.15</td></tr><tr><td> Carbofuran</td><td>26</td><td>0.91<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.52–1.59)</td><td>0%</td><td>0.94</td><td>57</td><td>1.21<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.83–1.78)</td><td>0%</td><td>0.70</td></tr><tr><td> Pirimicarb</td><td>58</td><td>0.84<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.41–1.71)</td><td>0%</td><td>0.96</td><td>185</td><td>1.01<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.70–1.46)</td><td>0%</td><td>0.68</td></tr><tr><td>OC insecticides</td><td>114</td><td>0.87</td><td>(0.54–1.40)</td><td>0%</td><td>0.82</td><td>290</td><td>1.03</td><td>(0.76–1.40)</td><td>0%</td><td>0.97</td></tr><tr><td> DDT</td><td>79</td><td>0.78</td><td>(0.45–1.37)</td><td>38%</td><td>0.20</td><td>230</td><td>0.96</td><td>(0.74–1.25)</td><td>0%</td><td>0.86</td></tr><tr><td> Lindane</td><td>78</td><td>0.92</td><td>(0.61–1.38)</td><td>0%</td><td>0.57</td><td>216</td><td>0.97</td><td>(0.74–1.28)</td><td>0%</td><td>0.89</td></tr><tr><td>Pyrethroid insecticides</td><td>81</td><td>1.16</td><td>(0.75–1.79)</td><td>0%</td><td>0.87</td><td>210</td><td>1.07</td><td>(0.79–1.46)</td><td>0%</td><td>0.72</td></tr><tr><td> Deltamethrin</td><td>46</td><td>1.09<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.64–1.87)</td><td>0%</td><td>0.77</td><td>135</td><td>0.93<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.69–1.24)</td><td>0%</td><td>0.97</td></tr><tr><td> Esfenvalerate</td><td>41</td><td>1.04<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.61–1.75)</td><td>0%</td><td>0.44</td><td>120</td><td>1.65</td><td>(0.61–4.41)</td><td>89%</td><td>0.00</td></tr><tr><td> Permethrin</td><td>60</td><td>0.79</td><td>(0.42–1.50)</td><td>26%</td><td>0.26</td><td>187</td><td>1.18</td><td>(0.86–1.63)</td><td>0%</td><td>0.61</td></tr><tr><td>(Phenyl) urea herbicides</td><td>81</td><td>1.09</td><td>(0.65–1.82)</td><td>0%</td><td>0.84</td><td>227</td><td>1.08</td><td>(0.79–1.47)</td><td>0%</td><td>0.65</td></tr><tr><td> Isoproturon</td><td>28</td><td>0.70<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.36–1.36)</td><td>0%</td><td>0.90</td><td>100</td><td>1.04<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.72–1.52)</td><td>0%</td><td>0.78</td></tr><tr><td> Linuron</td><td>79</td><td>1.11</td><td>(0.66–1.87)</td><td>0%</td><td>0.76</td><td>224</td><td>1.13</td><td>(0.81–1.57)</td><td>0%</td><td>0.78</td></tr><tr><td>Dicamba</td><td>73</td><td>0.81</td><td>(0.53–1.23)</td><td>0%</td><td>0.63</td><td>179</td><td>1.21</td><td>(0.93–1.59)</td><td>0%</td><td>0.92</td></tr><tr><td>Chloroacetanilides</td><td>78</td><td>1.00</td><td>(0.63–1.58)</td><td>0%</td><td>0.92</td><td>147</td><td>0.94</td><td>(0.71–1.25)</td><td>0%</td><td>0.88</td></tr><tr><td> Alachlor</td><td>43</td><td>0.86<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.47–1.56)</td><td>0%</td><td>0.96</td><td>78</td><td>1.06<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.73–1.54)</td><td>0%</td><td>0.94</td></tr><tr><td> Metolachlor</td><td>43</td><td>1.05<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.59–1.86)</td><td>0%</td><td>0.90</td><td>71</td><td>1.05<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.71–1.53)</td><td>0%</td><td>0.71</td></tr><tr><td>Dinitroaniline herbicides</td><td>57</td><td>0.99<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.56–1.74)</td><td>0%</td><td>0.71</td><td>95</td><td>0.82<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.42–1.61)</td><td>69%</td><td>0.07</td></tr><tr><td> Trifluralin</td><td>39</td><td>0.80<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.47–1.35)</td><td>0%</td><td>0.66</td><td>70</td><td>0.89<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.60–1.32)</td><td>0%</td><td>0.44</td></tr><tr><td>Glyphosate</td><td>105</td><td>0.79</td><td>(0.52–1.21)</td><td>0%</td><td>0.56</td><td>240</td><td>0.87</td><td>(0.66–1.15)</td><td>0%</td><td>0.95</td></tr><tr><td>Phenoxy herbicides</td><td>115</td><td>1.02</td><td>(0.60–1.75)</td><td>0%</td><td>0.95</td><td>257</td><td>0.77</td><td>(0.49–1.22)</td><td>43%</td><td>0.18</td></tr><tr><td> 2, 4-D</td><td>113</td><td>1.14</td><td>(0.67–1.96)</td><td>0%</td><td>0.91</td><td>250</td><td>0.90</td><td>(0.65–1.26)</td><td>0%</td><td>0.53</td></tr><tr><td> MCPA</td><td>60</td><td>1.21<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.53–2.80)</td><td>6%</td><td>0.30</td><td>174</td><td>0.69<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.29–1.64)</td><td>64%</td><td>0.10</td></tr><tr><td> MCPP</td><td>59</td><td>0.96<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.25–3.61)</td><td>58%</td><td>0.13</td><td>175</td><td>0.82<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.25–2.67)</td><td>82%</td><td>0.02</td></tr><tr><td>Thiocarbamate herbicides</td><td>88</td><td>0.81</td><td>(0.52–1.26)</td><td>0%</td><td>0.68</td><td>225</td><td>0.99</td><td>(0.73–1.34)</td><td>0%</td><td>0.80</td></tr><tr><td> Butylate</td><td>31</td><td>1.06<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.63–1.77)</td><td>0%</td><td>0.94</td><td>54</td><td>1.04<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.70–1.53)</td><td>0%</td><td>0.69</td></tr><tr><td> EPTC</td><td>49</td><td>0.86</td><td>(0.42–1.73)</td><td>51%</td><td>0.13</td><td>138</td><td>1.19</td><td>(0.90–1.59)</td><td>0%</td><td>0.87</td></tr><tr><td>Triazine herbicides</td><td>115</td><td>1.45</td><td>(0.62–3.39)</td><td>56%</td><td>0.10</td><td>246</td><td>0.82</td><td>(0.50–1.35)</td><td>56%</td><td>0.10</td></tr><tr><td> Atrazine</td><td>65</td><td>1.28<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.69–2.38)</td><td>0%</td><td>0.79</td><td>108</td><td>0.98<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.62–1.55)</td><td>0%</td><td>0.54</td></tr><tr><td> Simazine</td><td>23</td><td>0.91</td><td>(0.48–1.70)</td><td>0%</td><td>0.88</td><td>66</td><td>0.83</td><td>(0.52–1.32)</td><td>35%</td><td>0.22</td></tr><tr><td>Triazinone herbicides</td><td>86</td><td>0.85</td><td>(0.54–1.36)</td><td>0%</td><td>0.41</td><td>221</td><td>1.20</td><td>(0.73–1.97)</td><td>51%</td><td>0.13</td></tr><tr><td> Metribuzin</td><td>86</td><td>0.86</td><td>(0.54–1.36)</td><td>0%</td><td>0.41</td><td>221</td><td>1.20</td><td>(0.74–1.97)</td><td>51%</td><td>0.13</td></tr><tr><td>Dithiocarbamate fungicides</td><td>75</td><td>0.88</td><td>(0.52–1.49)</td><td>0%</td><td>0.98</td><td>229</td><td>1.11</td><td>(0.80–1.52)</td><td>0%</td><td>0.74</td></tr><tr><td> Mancozeb</td><td>71</td><td>0.80</td><td>(0.46–1.39)</td><td>0%</td><td>0.90</td><td>222</td><td>1.07</td><td>(0.78–1.48)</td><td>0%</td><td>0.64</td></tr><tr><td> Thiram</td><td>17</td><td>0.84<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.40–1.79)</td><td>0%</td><td>0.72</td><td>58</td><td>0.80<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.40–1.61)</td><td>60%</td><td>0.12</td></tr><tr><td>Phthalimide fungicides</td><td>71</td><td>0.73<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.37–1.44)</td><td>0%</td><td>0.84</td><td>216</td><td>1.05</td><td>(0.71–1.54)</td><td>0%</td><td>0.81</td></tr><tr><td> Captafol</td><td>62</td><td>1.11<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.51–2.42)</td><td>10%</td><td>0.29</td><td>192</td><td>1.13<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.76–1.68)</td><td>0%</td><td>0.45</td></tr><tr><td> Captan</td><td>36</td><td>0.90</td><td>(0.47–1.72)</td><td>0%</td><td>0.59</td><td>97</td><td>0.73</td><td>(0.39–1.37)</td><td>48%</td><td>0.15</td></tr><tr><td>Arsenicals</td><td>17</td><td></td><td></td><td></td><td></td><td>65</td><td>0.91<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.59–1.40)</td><td>0%</td><td>0.84</td></tr><tr><td colspan=\"11\"><hr></td></tr></tbody></table></div><div class=\"table-wrap-foot\"><span id=\"fn-tblfn5\"></span><div content-id=\"tblfn5\" class=\"footnote\"><span class=\"fn\"><p class=\"chapter-para\">AGRICAN: Cox regression adjusted for: sex, livestock, retirement status, number of selected types of crops for which pesticide treatment personally applied.</p></span></div><span id=\"fn-tblfn6\"></span><div content-id=\"tblfn6\" class=\"footnote\"><span class=\"fn\"><p class=\"chapter-para\">CNAP: Cox regression adjusted for: sex, livestock, dichlorvos, aldicarb, lindane, DDT, deltametrin, mancozeb, linuron, glyphosate.</p></span></div><span id=\"fn-tblfn7\"></span><div content-id=\"tblfn7\" class=\"footnote\"><span class=\"fn\"><p class=\"chapter-para\">AHS: Cox regression adjusted for: sex, state, livestock, terbufos, lindane, DDT, permethrin, dicamba, parathion, carbaryl.</p></span></div><span id=\"fn-tblfn8\"></span><div content-id=\"tblfn8\" class=\"footnote\"><span class=\"fn\"><p class=\"chapter-para\">mHR estimates for DLBCL in association with MCPA and MCPP not available because statistical models did not converge.</p></span></div><span id=\"fn-tblfn9\"></span><div content-id=\"tblfn9\" class=\"footnote\"><span class=\"fn\"><p class=\"chapter-para\">mHR estimate for FL in association with arsenicals not available because an estimate could be computed in only one (AGRICAN) of three cohorts. OC, organochlorine; OP, organophosphate; I<sup>2</sup> (I-squared, variation in meta-estimate attributable to heterogeneity).</p></span></div><span id=\"fn-tblfn10\"></span><div content-id=\"tblfn10\" class=\"footnote\"><span class=\"fn\"><p class=\"chapter-para\"><sup>a</sup>Number of cancer cases.</p></span></div><span id=\"fn-tblfn11\"></span><div content-id=\"tblfn11\" class=\"footnote\"><span class=\"fn\"><p class=\"chapter-para\"><sup>b</sup>Hazard ratio: random effects meta-analysis (fully adjusted models).</p></span></div><span id=\"fn-tblfn12\"></span><div content-id=\"tblfn12\" class=\"footnote\"><span class=\"fn\"><p class=\"chapter-para\"><sup>c</sup>Meta-analysis based on AGRICAN and CNAP only. For esfenvalerate, AHS contributed to mHR of NHL and multiple myeloma.</p></span></div><span id=\"fn-tblfn13\"></span><div content-id=\"tblfn13\" class=\"footnote\"><span class=\"fn\"><p class=\"chapter-para\"><sup>d</sup>Meta-analysis based on AGRICAN and AHS only.</p></span></div><span id=\"fn-tblfn14\"></span><div content-id=\"tblfn14\" class=\"footnote\"><span class=\"fn\"><p class=\"chapter-para\"><sup>e</sup><em>P</em>-value for heterogeneity.</p></span></div></div><div class=\"\n", | |
| " graphic-wrap\n", | |
| " \"><a class=\"fig-view-orig at-tableViewLarge openInAnotherWindow btn js-view-large\" target=\"_blank\" href=\"\n", | |
| " /view-large/[XSLTSectionID][QueryString]\" data-google-interstitial=\"false\">\n", | |
| " Open in new tab\n", | |
| " </a></div></div></div><div class=\"table-full-width-wrap\"><div class=\"table-wrap standard-table\"><div class=\"table-wrap-title\" id=\"dyz017-T2\" data-id=\"dyz017-T2\"><span class=\"label title-label\" id=\"label-24986\">Table 2.</span><div class=\"caption caption-id-\" id=\"caption-24986\"><p class=\"chapter-para\">Ever use of 14 pesticide chemical groups and 33 active ingredients and meta-risk estimates, fully adjusted, of non-Hodgkin lymphoid malignancies diagnosed during follow-up in farmers and farm workers in three cohort studies from France, Norway and the USA</p></div> </div><div class=\"table-overflow\"><table role=\"table\" aria-labelledby=\"\n", | |
| " label-24986\" aria-describedby=\"\n", | |
| " caption-24986\"><thead><tr><th><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th colspan=\"5\">Non-Hodgkin lymphoid malignancies (NHL)<hr><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th colspan=\"5\">Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)<hr><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th colspan=\"5\">Diffuse large B-cell lymphoma (DLBCL)<hr><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th></tr><tr><th><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>N</em><sup>a</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>HR<sup>b</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>95% CI<span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>I<span class=\"xrefLink\" id=\"jumplink-dyz017-B2\"></span><sup>2</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>P</em><sup>e</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>N</em><sup>a</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>HR<sup>b</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>95% CI<span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>I<span class=\"xrefLink\" id=\"jumplink-dyz017-B2\"></span><sup>2</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>P</em><sup>e</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>N</em><sup>a</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>HR<sup>b</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>95% CI<span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>I<span class=\"xrefLink\" id=\"jumplink-dyz017-B2\"></span><sup>2</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>P</em><sup>e</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th></tr></thead><tbody><tr><td>OP Insecticides</td><td>1417</td><td>0.90</td><td>(0.75–1.09)</td><td>0%</td><td>0.56</td><td>318</td><td>1.03</td><td>(0.64–1.65)</td><td>0%</td><td>0.65</td><td>256</td><td>0.90</td><td>(0.58–1.39)</td><td>0%</td><td>0.71</td></tr><tr><td> Chlorpyrifos</td><td>453</td><td>0.99<sup>d</sup></td><td>(0.86–1.15)</td><td>0%</td><td>0.51</td><td>106</td><td>1.05<sup>d</sup></td><td>(0.77–1.42)</td><td>0%</td><td>0.84</td><td>86</td><td>0.99<sup>d</sup></td><td>(0.72–1.36)</td><td>0%</td><td>0.76</td></tr><tr><td> Dichlorvos</td><td>523</td><td>1.10</td><td>(0.95–1.27)</td><td>0%</td><td>0.72</td><td>116</td><td>1.07</td><td>(0.78–1.46)</td><td>0%</td><td>0.39</td><td>81</td><td>0.94</td><td>(0.67–1.32)</td><td>0%</td><td>0.84</td></tr><tr><td> Malathion</td><td>1208</td><td>0.98</td><td>(0.82–1.16)</td><td>0%</td><td>0.54</td><td>274</td><td>1.11</td><td>(0.76–1.64)</td><td>0%</td><td>0.89</td><td>209</td><td>0.84</td><td>(0.58–1.21)</td><td>0%</td><td>0.86</td></tr><tr><td> Parathion</td><td>995</td><td>0.95</td><td>(0.81–1.11)</td><td>0%</td><td>0.58</td><td>210</td><td>0.99</td><td>(0.70–1.40)</td><td>0%</td><td>0.93</td><td>162</td><td>0.91</td><td>(0.63–1.31)</td><td>0%</td><td>0.92</td></tr><tr><td> Terbufos</td><td>300</td><td>1.18<sup>d</sup></td><td>(1.00–1.39)</td><td>0%</td><td>0.53</td><td>76</td><td>1.28<sup>d</sup></td><td>(0.92–1.79)</td><td>0%</td><td>1.00</td><td>56</td><td>1.08<sup>d</sup></td><td>(0.74–1.57)</td><td>0%</td><td>0.57</td></tr><tr><td>Carbamate insecticides</td><td>1254</td><td>0.94</td><td>(0.81–1.08)</td><td>0%</td><td>0.97</td><td>283</td><td>1.06</td><td>(0.75–1.48)</td><td>0%</td><td>1.00</td><td>219</td><td>0.79</td><td>(0.56–1.11)</td><td>0%</td><td>0.77</td></tr><tr><td> Aldicarb</td><td>526</td><td>1.09</td><td>(0.95–1.26)</td><td>0%</td><td>0.67</td><td>116</td><td>1.16</td><td>(0.84–1.60)</td><td>0%</td><td>0.93</td><td>82</td><td>0.88</td><td>(0.63–1.24)</td><td>0%</td><td>0.91</td></tr><tr><td> Carbaryl</td><td>651</td><td>0.95</td><td>(0.83–1.10)</td><td>0%</td><td>0.52</td><td>148</td><td>0.97</td><td>(0.71–1.34)</td><td>0%</td><td>0.67</td><td>125</td><td>0.87</td><td>(0.64–1.19)</td><td>0%</td><td>0.96</td></tr><tr><td> Carbofuran</td><td>254</td><td>1.00<sup>d</sup></td><td>(0.84–1.20)</td><td>0%</td><td>0.59</td><td>63</td><td>1.08<sup>d</sup></td><td>(0.75–1.56)</td><td>0%</td><td>0.40</td><td>44</td><td>0.84<sup>d</sup></td><td>(0.55–1.27)</td><td>0%</td><td>0.92</td></tr><tr><td> Pirimicarb</td><td>796</td><td>0.90<sup>c</sup></td><td>(0.74–1.08)</td><td>0%</td><td>0.95</td><td>176</td><td>1.18<sup>c</sup></td><td>(0.77–1.82)</td><td>0%</td><td>0.51</td><td>123</td><td>0.71<sup>c</sup></td><td>(0.44–1.14)</td><td>0%</td><td>0.64</td></tr><tr><td>OC insecticides</td><td>1258</td><td>0.86</td><td>(0.74–0.99)</td><td>0%</td><td>0.77</td><td>288</td><td>1.08</td><td>(0.79–1.48)</td><td>0%</td><td>0.83</td><td>215</td><td>0.79</td><td>(0.52–1.20)</td><td>35%</td><td>0.21</td></tr><tr><td> DDT</td><td>976</td><td>0.92</td><td>(0.81–1.04)</td><td>0%</td><td>0.71</td><td>220</td><td>1.00</td><td>(0.77–1.31)</td><td>0%</td><td>0.75</td><td>165</td><td>0.85</td><td>(0.63–1.14)</td><td>0%</td><td>0.74</td></tr><tr><td> Lindane</td><td>953</td><td>0.89</td><td>(0.78–1.01)</td><td>0%</td><td>0.87</td><td>217</td><td>1.06</td><td>(0.79–1.41)</td><td>0%</td><td>0.60</td><td>160</td><td>0.94</td><td>(0.68–1.30)</td><td>0%</td><td>0.47</td></tr><tr><td>Pyrethroid insecticides</td><td>934</td><td>1.04</td><td>(0.90–1.19)</td><td>2%</td><td>0.36</td><td>211</td><td>1.29</td><td>(0.90–1.84)</td><td>15%</td><td>0.31</td><td>153</td><td>0.92</td><td>(0.66–1.28)</td><td>0%</td><td>0.72</td></tr><tr><td> Deltamethrin</td><td>627</td><td>1.04<sup>c</sup></td><td>(0.82–1.33)</td><td>59%</td><td>0.12</td><td>148</td><td>1.48<sup>c</sup></td><td>(1.06–2.07)</td><td>0%</td><td>0.35</td><td>99</td><td>0.96<sup>c</sup></td><td>(0.68–1.37)</td><td>0%</td><td>0.64</td></tr><tr><td> Esfenvalerate</td><td>549</td><td>1.15</td><td>(0.82–1.63)</td><td>69%</td><td>0.04</td><td>124</td><td>1.24<sup>c</sup></td><td>(0.79–1.94)</td><td>36%</td><td>0.21</td><td>89</td><td>1.03<sup>c</sup></td><td>(0.71–1.50)</td><td>0%</td><td>0.93</td></tr><tr><td> Permethrin</td><td>812</td><td>1.01</td><td>(0.87–1.19)</td><td>0%</td><td>0.97</td><td>182</td><td>1.30</td><td>(0.85–2.00)</td><td>25%</td><td>0.26</td><td>131</td><td>0.89</td><td>(0.61–1.29)</td><td>0%</td><td>0.96</td></tr><tr><td>(Phenyl) urea herbicides</td><td>979</td><td>1.03</td><td>(0.89–1.19)</td><td>0%</td><td>0.48</td><td>209</td><td>1.07</td><td>(0.75–1.51)</td><td>0%</td><td>0.97</td><td>156</td><td>0.86</td><td>(0.61–1.21)</td><td>0%</td><td>0.87</td></tr><tr><td> Isoproturon</td><td>453</td><td>1.03<sup>c</sup></td><td>(0.78–1.35)</td><td>55%</td><td>0.14</td><td>109</td><td>1.19<sup>c</sup></td><td>(0.79–1.78)</td><td>0%</td><td>0.54</td><td>73</td><td>0.82<sup>c</sup></td><td>(0.49–1.38)</td><td>21%</td><td>0.26</td></tr><tr><td> Linuron</td><td>961</td><td>1.06</td><td>(0.90–1.24)</td><td>0%</td><td>0.46</td><td>204</td><td>1.05</td><td>(0.73–1.49)</td><td>0%</td><td>0.92</td><td>155</td><td>0.94</td><td>(0.67–1.33)</td><td>0%</td><td>0.88</td></tr><tr><td>Dicamba</td><td>815</td><td>1.04</td><td>(0.90–1.19)</td><td>10%</td><td>0.33</td><td>180</td><td>1.05</td><td>(0.80–1.38)</td><td>0%</td><td>0.83</td><td>142</td><td>0.95</td><td>(0.70–1.29)</td><td>0%</td><td>0.44</td></tr><tr><td>Chloroacetanilides</td><td>735</td><td>1.00</td><td>(0.87–1.14)</td><td>0%</td><td>0.79</td><td>161</td><td>0.96</td><td>(0.68–1.35)</td><td>21%</td><td>0.28</td><td>145</td><td>1.08</td><td>(0.79–1.47)</td><td>0%</td><td>0.68</td></tr><tr><td> Alachlor</td><td>380</td><td>0.97<sup>d</sup></td><td>(0.81–1.15)</td><td>0%</td><td>0.45</td><td>85</td><td>0.92<sup>d</sup></td><td>(0.43–1.96)</td><td>68%</td><td>0.07</td><td>74</td><td>0.87<sup>d</sup></td><td>(0.60–1.24)</td><td>0%</td><td>0.87</td></tr><tr><td> Metolachlor</td><td>358</td><td>0.99<sup>d</sup></td><td>(0.84–1.17)</td><td>0%</td><td>0.57</td><td>88</td><td>1.02<sup>d</sup></td><td>(0.72–1.43)</td><td>0%</td><td>0.45</td><td>71</td><td>0.95<sup>d</sup></td><td>(0.64–1.42)</td><td>0%</td><td>0.86</td></tr><tr><td>Dinitroaniline herbicides</td><td>506</td><td>0.94<sup>d</sup></td><td>(0.78–1.12)</td><td>0%</td><td>0.34</td><td>126</td><td>1.07<sup>d</sup></td><td>(0.74–1.56)</td><td>0%</td><td>0.42</td><td>101</td><td>0.91<sup>d</sup></td><td>(0.62–1.31)</td><td>0%</td><td>0.88</td></tr><tr><td> Trifluralin</td><td>368</td><td>0.98<sup>d</sup></td><td>(0.72–1.33)</td><td>64%</td><td>0.10</td><td>90</td><td>0.92<sup>d</sup></td><td>(0.60–1.41)</td><td>15%</td><td>0.28</td><td>72</td><td>0.90<sup>d</sup></td><td>(0.62–1.32)</td><td>0%</td><td>0.66</td></tr><tr><td>Glyphosate</td><td>1131</td><td>0.95</td><td>(0.77–1.18)</td><td>57%</td><td>0.10</td><td>252</td><td>0.92</td><td>(0.69–1.24)</td><td>0%</td><td>0.38</td><td>221</td><td>1.36</td><td>(1.00–1.85)</td><td>0%</td><td>0.48</td></tr><tr><td>Phenoxy herbicides</td><td>1204</td><td>0.81</td><td>(0.67–0.98)</td><td>19%</td><td>0.29</td><td>272</td><td>0.89</td><td>(0.61–1.31)</td><td>0%</td><td>0.79</td><td>218</td><td>0.70</td><td>(0.32–1.52)</td><td>59%</td><td>0.09</td></tr><tr><td> 2, 4-D</td><td>1167</td><td>0.88</td><td>(0.75–1.04)</td><td>0%</td><td>0.87</td><td>262</td><td>0.92</td><td>(0.61–1.39)</td><td>19%</td><td>0.29</td><td>212</td><td>0.77</td><td>(0.46–1.30)</td><td>47%</td><td>0.15</td></tr><tr><td> MCPA</td><td>775</td><td>0.81<sup>c</sup></td><td>(0.53–1.23)</td><td>65%</td><td>0.09</td><td>163</td><td>0.98<sup>c</sup></td><td>(0.54–1.77)</td><td>0%</td><td>0.83</td><td>125</td><td></td><td></td><td></td><td></td></tr><tr><td> MCPP</td><td>776</td><td>0.94</td><td>(0.61–1.46)</td><td>65%</td><td>0.06</td><td>163</td><td>1.06<sup>c</sup></td><td>(0.57–1.98)</td><td>0%</td><td>0.63</td><td>124</td><td></td><td></td><td></td><td></td></tr><tr><td>Thiocarbamate herbicides</td><td>1015</td><td>0.93</td><td>(0.80–1.08)</td><td>0%</td><td>0.69</td><td>225</td><td>0.95</td><td>(0.63–1.45)</td><td>34%</td><td>0.22</td><td>171</td><td>0.88</td><td>(0.61–1.25)</td><td>0%</td><td>0.88</td></tr><tr><td> Butylate</td><td>265</td><td>1.01<sup>d</sup></td><td>(0.85–1.19)</td><td>0%</td><td>0.52</td><td>60</td><td>0.96<sup>d</sup></td><td>(0.50–1.85)</td><td>56%</td><td>0.13</td><td>48</td><td>0.89<sup>d</sup></td><td>(0.61–1.32)</td><td>0%</td><td>0.92</td></tr><tr><td> EPTC</td><td>606</td><td>1.04</td><td>(0.91–1.19)</td><td>0%</td><td>0.74</td><td>133</td><td>1.10</td><td>(0.76–1.60)</td><td>35%</td><td>0.21</td><td>101</td><td>1.12</td><td>(0.81–1.56)</td><td>0%</td><td>0.69</td></tr><tr><td>Triazine herbicides</td><td>1165</td><td>0.87</td><td>(0.74–1.02)</td><td>8%</td><td>0.34</td><td>269</td><td>0.85</td><td>(0.60–1.20)</td><td>0%</td><td>0.72</td><td>212</td><td>0.84</td><td>(0.60–1.18)</td><td>0%</td><td>0.40</td></tr><tr><td> Atrazine</td><td>546</td><td>0.97<sup>d</sup></td><td>(0.79–1.18)</td><td>0%</td><td>0.99</td><td>131</td><td>0.96<sup>d</sup></td><td>(0.62–1.49)</td><td>0%</td><td>0.35</td><td>109</td><td>0.88<sup>d</sup></td><td>(0.59–1.31)</td><td>0%</td><td>0.54</td></tr><tr><td> Simazine</td><td>303</td><td>0.92</td><td>(0.77–1.09)</td><td>0%</td><td>0.43</td><td>63</td><td>0.83</td><td>(0.53–1.31)</td><td>6%</td><td>0.35</td><td>54</td><td>0.91</td><td>(0.61–1.36)</td><td>0%</td><td>0.65</td></tr><tr><td>Triazinone herbicides</td><td>971</td><td>1.09</td><td>(0.85–1.40)</td><td>60%</td><td>0.08</td><td>215</td><td>1.22</td><td>(0.84–1.77)</td><td>21%</td><td>0.28</td><td>157</td><td>1.00</td><td>(0.73–1.36)</td><td>0%</td><td>0.67</td></tr><tr><td> Metribuzin</td><td>971</td><td>1.09</td><td>(0.85–1.40)</td><td>60%</td><td>0.08</td><td>215</td><td>1.22</td><td>(0.84–1.77)</td><td>21%</td><td>0.28</td><td>157</td><td>1.00</td><td>(0.73–1.36)</td><td>0%</td><td>0.67</td></tr><tr><td>Dithiocarbamate fungicides</td><td>961</td><td>0.96</td><td>(0.83–1.11)</td><td>0%</td><td>0.96</td><td>196</td><td>0.86</td><td>(0.62–1.19)</td><td>0%</td><td>0.72</td><td>157</td><td>0.93</td><td>(0.66–1.31)</td><td>0%</td><td>0.60</td></tr><tr><td> Mancozeb</td><td>932</td><td>0.94</td><td>(0.81–1.09)</td><td>0%</td><td>0.85</td><td>193</td><td>0.90</td><td>(0.64–1.26)</td><td>0%</td><td>0.66</td><td>149</td><td>0.87</td><td>(0.62–1.21)</td><td>0%</td><td>0.87</td></tr><tr><td> Thiram</td><td>264</td><td>0.89<sup>c</sup></td><td>(0.73–1.07)</td><td>0%</td><td>0.35</td><td>54</td><td>0.82<sup>c</sup></td><td>(0.40–1.66)</td><td>50%</td><td>0.16</td><td>42</td><td>0.79<sup>c</sup></td><td>(0.50–1.25)</td><td>0%</td><td>0.54</td></tr><tr><td>Phthalimide fungicides</td><td>921</td><td>1.10</td><td>(0.80–1.52)</td><td>57%</td><td>0.10</td><td>193</td><td>1.13</td><td>(0.74–1.72)</td><td>0%</td><td>0.47</td><td>144</td><td>0.98</td><td>(0.65–1.47)</td><td>0%</td><td>0.94</td></tr><tr><td> Captafol</td><td>800</td><td>1.12<sup>c</sup></td><td>(0.79–1.59)</td><td>69%</td><td>0.07</td><td>162</td><td>1.20<sup>c</sup></td><td>(0.71–2.03)</td><td>23%</td><td>0.25</td><td>121</td><td>0.93<sup>c</sup></td><td>(0.62–1.41)</td><td>0%</td><td>0.44</td></tr><tr><td> Captan</td><td>481</td><td>0.90</td><td>(0.74–1.10)</td><td>0%</td><td>0.45</td><td>107</td><td>0.92</td><td>(0.59–1.44)</td><td>13%</td><td>0.32</td><td>74</td><td>0.83</td><td>(0.52–1.33)</td><td>0%</td><td>0.68</td></tr><tr><td>Arsenicals</td><td>272</td><td><hr>0.97<sup>d</sup><hr></td><td><hr>(0.79–1.18)</td><td><hr>0%</td><td><hr>0.71</td><td>60</td><td>1.04<sup>d</sup></td><td>(0.66–1.63)</td><td>0%</td><td>0.49</td><td>52</td><td>1.19<sup>d</sup></td><td>(0.73–1.95)</td><td><hr>0%</td><td><hr>0.64</td></tr><tr><td colspan=\"16\"><hr></td></tr></tbody></table></div><div class=\"table-modal\"><table><thead><tr><th><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th colspan=\"5\">Non-Hodgkin lymphoid malignancies (NHL)<hr><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th colspan=\"5\">Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)<hr><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th colspan=\"5\">Diffuse large B-cell lymphoma (DLBCL)<hr><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th></tr><tr><th><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>N</em><sup>a</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>HR<sup>b</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>95% CI<span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>I<span class=\"xrefLink\" id=\"jumplink-dyz017-B2\"></span><sup>2</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>P</em><sup>e</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>N</em><sup>a</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>HR<sup>b</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>95% CI<span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>I<span class=\"xrefLink\" id=\"jumplink-dyz017-B2\"></span><sup>2</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>P</em><sup>e</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>N</em><sup>a</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>HR<sup>b</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>95% CI<span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>I<span class=\"xrefLink\" id=\"jumplink-dyz017-B2\"></span><sup>2</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>P</em><sup>e</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th></tr></thead><tbody><tr><td>OP Insecticides</td><td>1417</td><td>0.90</td><td>(0.75–1.09)</td><td>0%</td><td>0.56</td><td>318</td><td>1.03</td><td>(0.64–1.65)</td><td>0%</td><td>0.65</td><td>256</td><td>0.90</td><td>(0.58–1.39)</td><td>0%</td><td>0.71</td></tr><tr><td> Chlorpyrifos</td><td>453</td><td>0.99<sup>d</sup></td><td>(0.86–1.15)</td><td>0%</td><td>0.51</td><td>106</td><td>1.05<sup>d</sup></td><td>(0.77–1.42)</td><td>0%</td><td>0.84</td><td>86</td><td>0.99<sup>d</sup></td><td>(0.72–1.36)</td><td>0%</td><td>0.76</td></tr><tr><td> Dichlorvos</td><td>523</td><td>1.10</td><td>(0.95–1.27)</td><td>0%</td><td>0.72</td><td>116</td><td>1.07</td><td>(0.78–1.46)</td><td>0%</td><td>0.39</td><td>81</td><td>0.94</td><td>(0.67–1.32)</td><td>0%</td><td>0.84</td></tr><tr><td> Malathion</td><td>1208</td><td>0.98</td><td>(0.82–1.16)</td><td>0%</td><td>0.54</td><td>274</td><td>1.11</td><td>(0.76–1.64)</td><td>0%</td><td>0.89</td><td>209</td><td>0.84</td><td>(0.58–1.21)</td><td>0%</td><td>0.86</td></tr><tr><td> Parathion</td><td>995</td><td>0.95</td><td>(0.81–1.11)</td><td>0%</td><td>0.58</td><td>210</td><td>0.99</td><td>(0.70–1.40)</td><td>0%</td><td>0.93</td><td>162</td><td>0.91</td><td>(0.63–1.31)</td><td>0%</td><td>0.92</td></tr><tr><td> Terbufos</td><td>300</td><td>1.18<sup>d</sup></td><td>(1.00–1.39)</td><td>0%</td><td>0.53</td><td>76</td><td>1.28<sup>d</sup></td><td>(0.92–1.79)</td><td>0%</td><td>1.00</td><td>56</td><td>1.08<sup>d</sup></td><td>(0.74–1.57)</td><td>0%</td><td>0.57</td></tr><tr><td>Carbamate insecticides</td><td>1254</td><td>0.94</td><td>(0.81–1.08)</td><td>0%</td><td>0.97</td><td>283</td><td>1.06</td><td>(0.75–1.48)</td><td>0%</td><td>1.00</td><td>219</td><td>0.79</td><td>(0.56–1.11)</td><td>0%</td><td>0.77</td></tr><tr><td> Aldicarb</td><td>526</td><td>1.09</td><td>(0.95–1.26)</td><td>0%</td><td>0.67</td><td>116</td><td>1.16</td><td>(0.84–1.60)</td><td>0%</td><td>0.93</td><td>82</td><td>0.88</td><td>(0.63–1.24)</td><td>0%</td><td>0.91</td></tr><tr><td> Carbaryl</td><td>651</td><td>0.95</td><td>(0.83–1.10)</td><td>0%</td><td>0.52</td><td>148</td><td>0.97</td><td>(0.71–1.34)</td><td>0%</td><td>0.67</td><td>125</td><td>0.87</td><td>(0.64–1.19)</td><td>0%</td><td>0.96</td></tr><tr><td> Carbofuran</td><td>254</td><td>1.00<sup>d</sup></td><td>(0.84–1.20)</td><td>0%</td><td>0.59</td><td>63</td><td>1.08<sup>d</sup></td><td>(0.75–1.56)</td><td>0%</td><td>0.40</td><td>44</td><td>0.84<sup>d</sup></td><td>(0.55–1.27)</td><td>0%</td><td>0.92</td></tr><tr><td> Pirimicarb</td><td>796</td><td>0.90<sup>c</sup></td><td>(0.74–1.08)</td><td>0%</td><td>0.95</td><td>176</td><td>1.18<sup>c</sup></td><td>(0.77–1.82)</td><td>0%</td><td>0.51</td><td>123</td><td>0.71<sup>c</sup></td><td>(0.44–1.14)</td><td>0%</td><td>0.64</td></tr><tr><td>OC insecticides</td><td>1258</td><td>0.86</td><td>(0.74–0.99)</td><td>0%</td><td>0.77</td><td>288</td><td>1.08</td><td>(0.79–1.48)</td><td>0%</td><td>0.83</td><td>215</td><td>0.79</td><td>(0.52–1.20)</td><td>35%</td><td>0.21</td></tr><tr><td> DDT</td><td>976</td><td>0.92</td><td>(0.81–1.04)</td><td>0%</td><td>0.71</td><td>220</td><td>1.00</td><td>(0.77–1.31)</td><td>0%</td><td>0.75</td><td>165</td><td>0.85</td><td>(0.63–1.14)</td><td>0%</td><td>0.74</td></tr><tr><td> Lindane</td><td>953</td><td>0.89</td><td>(0.78–1.01)</td><td>0%</td><td>0.87</td><td>217</td><td>1.06</td><td>(0.79–1.41)</td><td>0%</td><td>0.60</td><td>160</td><td>0.94</td><td>(0.68–1.30)</td><td>0%</td><td>0.47</td></tr><tr><td>Pyrethroid insecticides</td><td>934</td><td>1.04</td><td>(0.90–1.19)</td><td>2%</td><td>0.36</td><td>211</td><td>1.29</td><td>(0.90–1.84)</td><td>15%</td><td>0.31</td><td>153</td><td>0.92</td><td>(0.66–1.28)</td><td>0%</td><td>0.72</td></tr><tr><td> Deltamethrin</td><td>627</td><td>1.04<sup>c</sup></td><td>(0.82–1.33)</td><td>59%</td><td>0.12</td><td>148</td><td>1.48<sup>c</sup></td><td>(1.06–2.07)</td><td>0%</td><td>0.35</td><td>99</td><td>0.96<sup>c</sup></td><td>(0.68–1.37)</td><td>0%</td><td>0.64</td></tr><tr><td> Esfenvalerate</td><td>549</td><td>1.15</td><td>(0.82–1.63)</td><td>69%</td><td>0.04</td><td>124</td><td>1.24<sup>c</sup></td><td>(0.79–1.94)</td><td>36%</td><td>0.21</td><td>89</td><td>1.03<sup>c</sup></td><td>(0.71–1.50)</td><td>0%</td><td>0.93</td></tr><tr><td> Permethrin</td><td>812</td><td>1.01</td><td>(0.87–1.19)</td><td>0%</td><td>0.97</td><td>182</td><td>1.30</td><td>(0.85–2.00)</td><td>25%</td><td>0.26</td><td>131</td><td>0.89</td><td>(0.61–1.29)</td><td>0%</td><td>0.96</td></tr><tr><td>(Phenyl) urea herbicides</td><td>979</td><td>1.03</td><td>(0.89–1.19)</td><td>0%</td><td>0.48</td><td>209</td><td>1.07</td><td>(0.75–1.51)</td><td>0%</td><td>0.97</td><td>156</td><td>0.86</td><td>(0.61–1.21)</td><td>0%</td><td>0.87</td></tr><tr><td> Isoproturon</td><td>453</td><td>1.03<sup>c</sup></td><td>(0.78–1.35)</td><td>55%</td><td>0.14</td><td>109</td><td>1.19<sup>c</sup></td><td>(0.79–1.78)</td><td>0%</td><td>0.54</td><td>73</td><td>0.82<sup>c</sup></td><td>(0.49–1.38)</td><td>21%</td><td>0.26</td></tr><tr><td> Linuron</td><td>961</td><td>1.06</td><td>(0.90–1.24)</td><td>0%</td><td>0.46</td><td>204</td><td>1.05</td><td>(0.73–1.49)</td><td>0%</td><td>0.92</td><td>155</td><td>0.94</td><td>(0.67–1.33)</td><td>0%</td><td>0.88</td></tr><tr><td>Dicamba</td><td>815</td><td>1.04</td><td>(0.90–1.19)</td><td>10%</td><td>0.33</td><td>180</td><td>1.05</td><td>(0.80–1.38)</td><td>0%</td><td>0.83</td><td>142</td><td>0.95</td><td>(0.70–1.29)</td><td>0%</td><td>0.44</td></tr><tr><td>Chloroacetanilides</td><td>735</td><td>1.00</td><td>(0.87–1.14)</td><td>0%</td><td>0.79</td><td>161</td><td>0.96</td><td>(0.68–1.35)</td><td>21%</td><td>0.28</td><td>145</td><td>1.08</td><td>(0.79–1.47)</td><td>0%</td><td>0.68</td></tr><tr><td> Alachlor</td><td>380</td><td>0.97<sup>d</sup></td><td>(0.81–1.15)</td><td>0%</td><td>0.45</td><td>85</td><td>0.92<sup>d</sup></td><td>(0.43–1.96)</td><td>68%</td><td>0.07</td><td>74</td><td>0.87<sup>d</sup></td><td>(0.60–1.24)</td><td>0%</td><td>0.87</td></tr><tr><td> Metolachlor</td><td>358</td><td>0.99<sup>d</sup></td><td>(0.84–1.17)</td><td>0%</td><td>0.57</td><td>88</td><td>1.02<sup>d</sup></td><td>(0.72–1.43)</td><td>0%</td><td>0.45</td><td>71</td><td>0.95<sup>d</sup></td><td>(0.64–1.42)</td><td>0%</td><td>0.86</td></tr><tr><td>Dinitroaniline herbicides</td><td>506</td><td>0.94<sup>d</sup></td><td>(0.78–1.12)</td><td>0%</td><td>0.34</td><td>126</td><td>1.07<sup>d</sup></td><td>(0.74–1.56)</td><td>0%</td><td>0.42</td><td>101</td><td>0.91<sup>d</sup></td><td>(0.62–1.31)</td><td>0%</td><td>0.88</td></tr><tr><td> Trifluralin</td><td>368</td><td>0.98<sup>d</sup></td><td>(0.72–1.33)</td><td>64%</td><td>0.10</td><td>90</td><td>0.92<sup>d</sup></td><td>(0.60–1.41)</td><td>15%</td><td>0.28</td><td>72</td><td>0.90<sup>d</sup></td><td>(0.62–1.32)</td><td>0%</td><td>0.66</td></tr><tr><td>Glyphosate</td><td>1131</td><td>0.95</td><td>(0.77–1.18)</td><td>57%</td><td>0.10</td><td>252</td><td>0.92</td><td>(0.69–1.24)</td><td>0%</td><td>0.38</td><td>221</td><td>1.36</td><td>(1.00–1.85)</td><td>0%</td><td>0.48</td></tr><tr><td>Phenoxy herbicides</td><td>1204</td><td>0.81</td><td>(0.67–0.98)</td><td>19%</td><td>0.29</td><td>272</td><td>0.89</td><td>(0.61–1.31)</td><td>0%</td><td>0.79</td><td>218</td><td>0.70</td><td>(0.32–1.52)</td><td>59%</td><td>0.09</td></tr><tr><td> 2, 4-D</td><td>1167</td><td>0.88</td><td>(0.75–1.04)</td><td>0%</td><td>0.87</td><td>262</td><td>0.92</td><td>(0.61–1.39)</td><td>19%</td><td>0.29</td><td>212</td><td>0.77</td><td>(0.46–1.30)</td><td>47%</td><td>0.15</td></tr><tr><td> MCPA</td><td>775</td><td>0.81<sup>c</sup></td><td>(0.53–1.23)</td><td>65%</td><td>0.09</td><td>163</td><td>0.98<sup>c</sup></td><td>(0.54–1.77)</td><td>0%</td><td>0.83</td><td>125</td><td></td><td></td><td></td><td></td></tr><tr><td> MCPP</td><td>776</td><td>0.94</td><td>(0.61–1.46)</td><td>65%</td><td>0.06</td><td>163</td><td>1.06<sup>c</sup></td><td>(0.57–1.98)</td><td>0%</td><td>0.63</td><td>124</td><td></td><td></td><td></td><td></td></tr><tr><td>Thiocarbamate herbicides</td><td>1015</td><td>0.93</td><td>(0.80–1.08)</td><td>0%</td><td>0.69</td><td>225</td><td>0.95</td><td>(0.63–1.45)</td><td>34%</td><td>0.22</td><td>171</td><td>0.88</td><td>(0.61–1.25)</td><td>0%</td><td>0.88</td></tr><tr><td> Butylate</td><td>265</td><td>1.01<sup>d</sup></td><td>(0.85–1.19)</td><td>0%</td><td>0.52</td><td>60</td><td>0.96<sup>d</sup></td><td>(0.50–1.85)</td><td>56%</td><td>0.13</td><td>48</td><td>0.89<sup>d</sup></td><td>(0.61–1.32)</td><td>0%</td><td>0.92</td></tr><tr><td> EPTC</td><td>606</td><td>1.04</td><td>(0.91–1.19)</td><td>0%</td><td>0.74</td><td>133</td><td>1.10</td><td>(0.76–1.60)</td><td>35%</td><td>0.21</td><td>101</td><td>1.12</td><td>(0.81–1.56)</td><td>0%</td><td>0.69</td></tr><tr><td>Triazine herbicides</td><td>1165</td><td>0.87</td><td>(0.74–1.02)</td><td>8%</td><td>0.34</td><td>269</td><td>0.85</td><td>(0.60–1.20)</td><td>0%</td><td>0.72</td><td>212</td><td>0.84</td><td>(0.60–1.18)</td><td>0%</td><td>0.40</td></tr><tr><td> Atrazine</td><td>546</td><td>0.97<sup>d</sup></td><td>(0.79–1.18)</td><td>0%</td><td>0.99</td><td>131</td><td>0.96<sup>d</sup></td><td>(0.62–1.49)</td><td>0%</td><td>0.35</td><td>109</td><td>0.88<sup>d</sup></td><td>(0.59–1.31)</td><td>0%</td><td>0.54</td></tr><tr><td> Simazine</td><td>303</td><td>0.92</td><td>(0.77–1.09)</td><td>0%</td><td>0.43</td><td>63</td><td>0.83</td><td>(0.53–1.31)</td><td>6%</td><td>0.35</td><td>54</td><td>0.91</td><td>(0.61–1.36)</td><td>0%</td><td>0.65</td></tr><tr><td>Triazinone herbicides</td><td>971</td><td>1.09</td><td>(0.85–1.40)</td><td>60%</td><td>0.08</td><td>215</td><td>1.22</td><td>(0.84–1.77)</td><td>21%</td><td>0.28</td><td>157</td><td>1.00</td><td>(0.73–1.36)</td><td>0%</td><td>0.67</td></tr><tr><td> Metribuzin</td><td>971</td><td>1.09</td><td>(0.85–1.40)</td><td>60%</td><td>0.08</td><td>215</td><td>1.22</td><td>(0.84–1.77)</td><td>21%</td><td>0.28</td><td>157</td><td>1.00</td><td>(0.73–1.36)</td><td>0%</td><td>0.67</td></tr><tr><td>Dithiocarbamate fungicides</td><td>961</td><td>0.96</td><td>(0.83–1.11)</td><td>0%</td><td>0.96</td><td>196</td><td>0.86</td><td>(0.62–1.19)</td><td>0%</td><td>0.72</td><td>157</td><td>0.93</td><td>(0.66–1.31)</td><td>0%</td><td>0.60</td></tr><tr><td> Mancozeb</td><td>932</td><td>0.94</td><td>(0.81–1.09)</td><td>0%</td><td>0.85</td><td>193</td><td>0.90</td><td>(0.64–1.26)</td><td>0%</td><td>0.66</td><td>149</td><td>0.87</td><td>(0.62–1.21)</td><td>0%</td><td>0.87</td></tr><tr><td> Thiram</td><td>264</td><td>0.89<sup>c</sup></td><td>(0.73–1.07)</td><td>0%</td><td>0.35</td><td>54</td><td>0.82<sup>c</sup></td><td>(0.40–1.66)</td><td>50%</td><td>0.16</td><td>42</td><td>0.79<sup>c</sup></td><td>(0.50–1.25)</td><td>0%</td><td>0.54</td></tr><tr><td>Phthalimide fungicides</td><td>921</td><td>1.10</td><td>(0.80–1.52)</td><td>57%</td><td>0.10</td><td>193</td><td>1.13</td><td>(0.74–1.72)</td><td>0%</td><td>0.47</td><td>144</td><td>0.98</td><td>(0.65–1.47)</td><td>0%</td><td>0.94</td></tr><tr><td> Captafol</td><td>800</td><td>1.12<sup>c</sup></td><td>(0.79–1.59)</td><td>69%</td><td>0.07</td><td>162</td><td>1.20<sup>c</sup></td><td>(0.71–2.03)</td><td>23%</td><td>0.25</td><td>121</td><td>0.93<sup>c</sup></td><td>(0.62–1.41)</td><td>0%</td><td>0.44</td></tr><tr><td> Captan</td><td>481</td><td>0.90</td><td>(0.74–1.10)</td><td>0%</td><td>0.45</td><td>107</td><td>0.92</td><td>(0.59–1.44)</td><td>13%</td><td>0.32</td><td>74</td><td>0.83</td><td>(0.52–1.33)</td><td>0%</td><td>0.68</td></tr><tr><td>Arsenicals</td><td>272</td><td><hr>0.97<sup>d</sup><hr></td><td><hr>(0.79–1.18)</td><td><hr>0%</td><td><hr>0.71</td><td>60</td><td>1.04<sup>d</sup></td><td>(0.66–1.63)</td><td>0%</td><td>0.49</td><td>52</td><td>1.19<sup>d</sup></td><td>(0.73–1.95)</td><td><hr>0%</td><td><hr>0.64</td></tr><tr><td colspan=\"16\"><hr></td></tr></tbody></table></div><div class=\"table-overflow\"><table role=\"table\" aria-labelledby=\"\n", | |
| " label-24986\" aria-describedby=\"\n", | |
| " caption-24986\"><thead><tr><th><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th colspan=\"5\"><hr>Follicular lymphoma (FL)<hr><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th colspan=\"5\">Multiple myeloma/plasma-cell leukaemia (MM)<hr><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th></tr><tr><th><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>N</em><span class=\"xrefLink\" id=\"jumplink-tblfn7\"></span><a href=\"javascript:;\" reveal-id=\"tblfn7\" data-open=\"tblfn7\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>a</sup></a><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>HR<span class=\"xrefLink\" id=\"jumplink-tblfn8\"></span><a href=\"javascript:;\" reveal-id=\"tblfn8\" data-open=\"tblfn8\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>b</sup></a><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>95% CI<span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>I<span class=\"xrefLink\" id=\"jumplink-dyz017-B2\"></span><sup>2</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>P</em><span class=\"xrefLink\" id=\"jumplink-tblfn12\"></span><a href=\"javascript:;\" reveal-id=\"tblfn12\" data-open=\"tblfn12\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>e</sup></a><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>N</em><span class=\"xrefLink\" id=\"jumplink-tblfn7\"></span><a href=\"javascript:;\" reveal-id=\"tblfn7\" data-open=\"tblfn7\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>a</sup></a><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>HR<span class=\"xrefLink\" id=\"jumplink-tblfn8\"></span><a href=\"javascript:;\" reveal-id=\"tblfn8\" data-open=\"tblfn8\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>b</sup></a><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>95% CI<span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>I<span class=\"xrefLink\" id=\"jumplink-dyz017-B2\"></span><sup>2</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>P</em><span class=\"xrefLink\" id=\"jumplink-tblfn12\"></span><a href=\"javascript:;\" reveal-id=\"tblfn12\" data-open=\"tblfn12\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>e</sup></a><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th></tr></thead><tbody><tr><td>OP insecticides</td><td>131</td><td>0.78</td><td>(0.34–1.76)</td><td>2%</td><td>0.36</td><td>313</td><td>0.85</td><td>(0.56–1.29)</td><td>0%</td><td>0.83</td></tr><tr><td> Chlorpyrifos</td><td>46</td><td>1.08<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.68–1.70)</td><td>0%</td><td>0.58</td><td>97</td><td>0.93<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.66–1.32)</td><td>0%</td><td>0.73</td></tr><tr><td> Dichlorvos</td><td>40</td><td>1.10</td><td>(0.69–1.76)</td><td>0%</td><td>0.95</td><td>111</td><td>0.98</td><td>(0.70–1.37)</td><td>22%</td><td>0.28</td></tr><tr><td> Malathion</td><td>114</td><td>1.18</td><td>(0.66–2.10)</td><td>0%</td><td>0.64</td><td>269</td><td>0.95</td><td>(0.67–1.36)</td><td>0%</td><td>0.69</td></tr><tr><td> Parathion</td><td>83</td><td>1.24</td><td>(0.72–2.15)</td><td>0%</td><td>0.44</td><td>230</td><td>0.84</td><td>(0.57–1.24)</td><td>18%</td><td>0.30</td></tr><tr><td> Terbufos</td><td>35</td><td>1.33<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.80–2.20)</td><td>0%</td><td>0.70</td><td>55</td><td>1.01<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.69–1.49)</td><td>0%</td><td>0.64</td></tr><tr><td>Carbamate insecticides</td><td>115</td><td>1.03</td><td>(0.63–1.68)</td><td>0%</td><td>0.47</td><td>290</td><td>1.25</td><td>(0.89–1.75)</td><td>9%</td><td>0.33</td></tr><tr><td> Aldicarb</td><td>38</td><td>0.94</td><td>(0.56–1.56)</td><td>0%</td><td>0.79</td><td>113</td><td>0.91</td><td>(0.68–1.22)</td><td>0%</td><td>0.58</td></tr><tr><td> Carbaryl</td><td>67</td><td>1.27<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.66–2.43)</td><td>27%</td><td>0.24</td><td>152</td><td>1.11</td><td>(0.71–1.74)</td><td>47%</td><td>0.15</td></tr><tr><td> Carbofuran</td><td>26</td><td>0.91<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.52–1.59)</td><td>0%</td><td>0.94</td><td>57</td><td>1.21<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.83–1.78)</td><td>0%</td><td>0.70</td></tr><tr><td> Pirimicarb</td><td>58</td><td>0.84<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.41–1.71)</td><td>0%</td><td>0.96</td><td>185</td><td>1.01<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.70–1.46)</td><td>0%</td><td>0.68</td></tr><tr><td>OC insecticides</td><td>114</td><td>0.87</td><td>(0.54–1.40)</td><td>0%</td><td>0.82</td><td>290</td><td>1.03</td><td>(0.76–1.40)</td><td>0%</td><td>0.97</td></tr><tr><td> DDT</td><td>79</td><td>0.78</td><td>(0.45–1.37)</td><td>38%</td><td>0.20</td><td>230</td><td>0.96</td><td>(0.74–1.25)</td><td>0%</td><td>0.86</td></tr><tr><td> Lindane</td><td>78</td><td>0.92</td><td>(0.61–1.38)</td><td>0%</td><td>0.57</td><td>216</td><td>0.97</td><td>(0.74–1.28)</td><td>0%</td><td>0.89</td></tr><tr><td>Pyrethroid insecticides</td><td>81</td><td>1.16</td><td>(0.75–1.79)</td><td>0%</td><td>0.87</td><td>210</td><td>1.07</td><td>(0.79–1.46)</td><td>0%</td><td>0.72</td></tr><tr><td> Deltamethrin</td><td>46</td><td>1.09<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.64–1.87)</td><td>0%</td><td>0.77</td><td>135</td><td>0.93<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.69–1.24)</td><td>0%</td><td>0.97</td></tr><tr><td> Esfenvalerate</td><td>41</td><td>1.04<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.61–1.75)</td><td>0%</td><td>0.44</td><td>120</td><td>1.65</td><td>(0.61–4.41)</td><td>89%</td><td>0.00</td></tr><tr><td> Permethrin</td><td>60</td><td>0.79</td><td>(0.42–1.50)</td><td>26%</td><td>0.26</td><td>187</td><td>1.18</td><td>(0.86–1.63)</td><td>0%</td><td>0.61</td></tr><tr><td>(Phenyl) urea herbicides</td><td>81</td><td>1.09</td><td>(0.65–1.82)</td><td>0%</td><td>0.84</td><td>227</td><td>1.08</td><td>(0.79–1.47)</td><td>0%</td><td>0.65</td></tr><tr><td> Isoproturon</td><td>28</td><td>0.70<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.36–1.36)</td><td>0%</td><td>0.90</td><td>100</td><td>1.04<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.72–1.52)</td><td>0%</td><td>0.78</td></tr><tr><td> Linuron</td><td>79</td><td>1.11</td><td>(0.66–1.87)</td><td>0%</td><td>0.76</td><td>224</td><td>1.13</td><td>(0.81–1.57)</td><td>0%</td><td>0.78</td></tr><tr><td>Dicamba</td><td>73</td><td>0.81</td><td>(0.53–1.23)</td><td>0%</td><td>0.63</td><td>179</td><td>1.21</td><td>(0.93–1.59)</td><td>0%</td><td>0.92</td></tr><tr><td>Chloroacetanilides</td><td>78</td><td>1.00</td><td>(0.63–1.58)</td><td>0%</td><td>0.92</td><td>147</td><td>0.94</td><td>(0.71–1.25)</td><td>0%</td><td>0.88</td></tr><tr><td> Alachlor</td><td>43</td><td>0.86<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.47–1.56)</td><td>0%</td><td>0.96</td><td>78</td><td>1.06<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.73–1.54)</td><td>0%</td><td>0.94</td></tr><tr><td> Metolachlor</td><td>43</td><td>1.05<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.59–1.86)</td><td>0%</td><td>0.90</td><td>71</td><td>1.05<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.71–1.53)</td><td>0%</td><td>0.71</td></tr><tr><td>Dinitroaniline herbicides</td><td>57</td><td>0.99<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.56–1.74)</td><td>0%</td><td>0.71</td><td>95</td><td>0.82<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.42–1.61)</td><td>69%</td><td>0.07</td></tr><tr><td> Trifluralin</td><td>39</td><td>0.80<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.47–1.35)</td><td>0%</td><td>0.66</td><td>70</td><td>0.89<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.60–1.32)</td><td>0%</td><td>0.44</td></tr><tr><td>Glyphosate</td><td>105</td><td>0.79</td><td>(0.52–1.21)</td><td>0%</td><td>0.56</td><td>240</td><td>0.87</td><td>(0.66–1.15)</td><td>0%</td><td>0.95</td></tr><tr><td>Phenoxy herbicides</td><td>115</td><td>1.02</td><td>(0.60–1.75)</td><td>0%</td><td>0.95</td><td>257</td><td>0.77</td><td>(0.49–1.22)</td><td>43%</td><td>0.18</td></tr><tr><td> 2, 4-D</td><td>113</td><td>1.14</td><td>(0.67–1.96)</td><td>0%</td><td>0.91</td><td>250</td><td>0.90</td><td>(0.65–1.26)</td><td>0%</td><td>0.53</td></tr><tr><td> MCPA</td><td>60</td><td>1.21<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.53–2.80)</td><td>6%</td><td>0.30</td><td>174</td><td>0.69<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.29–1.64)</td><td>64%</td><td>0.10</td></tr><tr><td> MCPP</td><td>59</td><td>0.96<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.25–3.61)</td><td>58%</td><td>0.13</td><td>175</td><td>0.82<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.25–2.67)</td><td>82%</td><td>0.02</td></tr><tr><td>Thiocarbamate herbicides</td><td>88</td><td>0.81</td><td>(0.52–1.26)</td><td>0%</td><td>0.68</td><td>225</td><td>0.99</td><td>(0.73–1.34)</td><td>0%</td><td>0.80</td></tr><tr><td> Butylate</td><td>31</td><td>1.06<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.63–1.77)</td><td>0%</td><td>0.94</td><td>54</td><td>1.04<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.70–1.53)</td><td>0%</td><td>0.69</td></tr><tr><td> EPTC</td><td>49</td><td>0.86</td><td>(0.42–1.73)</td><td>51%</td><td>0.13</td><td>138</td><td>1.19</td><td>(0.90–1.59)</td><td>0%</td><td>0.87</td></tr><tr><td>Triazine herbicides</td><td>115</td><td>1.45</td><td>(0.62–3.39)</td><td>56%</td><td>0.10</td><td>246</td><td>0.82</td><td>(0.50–1.35)</td><td>56%</td><td>0.10</td></tr><tr><td> Atrazine</td><td>65</td><td>1.28<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.69–2.38)</td><td>0%</td><td>0.79</td><td>108</td><td>0.98<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.62–1.55)</td><td>0%</td><td>0.54</td></tr><tr><td> Simazine</td><td>23</td><td>0.91</td><td>(0.48–1.70)</td><td>0%</td><td>0.88</td><td>66</td><td>0.83</td><td>(0.52–1.32)</td><td>35%</td><td>0.22</td></tr><tr><td>Triazinone herbicides</td><td>86</td><td>0.85</td><td>(0.54–1.36)</td><td>0%</td><td>0.41</td><td>221</td><td>1.20</td><td>(0.73–1.97)</td><td>51%</td><td>0.13</td></tr><tr><td> Metribuzin</td><td>86</td><td>0.86</td><td>(0.54–1.36)</td><td>0%</td><td>0.41</td><td>221</td><td>1.20</td><td>(0.74–1.97)</td><td>51%</td><td>0.13</td></tr><tr><td>Dithiocarbamate fungicides</td><td>75</td><td>0.88</td><td>(0.52–1.49)</td><td>0%</td><td>0.98</td><td>229</td><td>1.11</td><td>(0.80–1.52)</td><td>0%</td><td>0.74</td></tr><tr><td> Mancozeb</td><td>71</td><td>0.80</td><td>(0.46–1.39)</td><td>0%</td><td>0.90</td><td>222</td><td>1.07</td><td>(0.78–1.48)</td><td>0%</td><td>0.64</td></tr><tr><td> Thiram</td><td>17</td><td>0.84<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.40–1.79)</td><td>0%</td><td>0.72</td><td>58</td><td>0.80<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.40–1.61)</td><td>60%</td><td>0.12</td></tr><tr><td>Phthalimide fungicides</td><td>71</td><td>0.73<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.37–1.44)</td><td>0%</td><td>0.84</td><td>216</td><td>1.05</td><td>(0.71–1.54)</td><td>0%</td><td>0.81</td></tr><tr><td> Captafol</td><td>62</td><td>1.11<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.51–2.42)</td><td>10%</td><td>0.29</td><td>192</td><td>1.13<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.76–1.68)</td><td>0%</td><td>0.45</td></tr><tr><td> Captan</td><td>36</td><td>0.90</td><td>(0.47–1.72)</td><td>0%</td><td>0.59</td><td>97</td><td>0.73</td><td>(0.39–1.37)</td><td>48%</td><td>0.15</td></tr><tr><td>Arsenicals</td><td>17</td><td></td><td></td><td></td><td></td><td>65</td><td>0.91<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.59–1.40)</td><td>0%</td><td>0.84</td></tr><tr><td colspan=\"11\"><hr></td></tr></tbody></table></div><div class=\"table-modal\"><table><thead><tr><th><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th colspan=\"5\"><hr>Follicular lymphoma (FL)<hr><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th colspan=\"5\">Multiple myeloma/plasma-cell leukaemia (MM)<hr><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th></tr><tr><th><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>N</em><span class=\"xrefLink\" id=\"jumplink-tblfn7\"></span><a href=\"javascript:;\" reveal-id=\"tblfn7\" data-open=\"tblfn7\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>a</sup></a><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>HR<span class=\"xrefLink\" id=\"jumplink-tblfn8\"></span><a href=\"javascript:;\" reveal-id=\"tblfn8\" data-open=\"tblfn8\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>b</sup></a><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>95% CI<span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>I<span class=\"xrefLink\" id=\"jumplink-dyz017-B2\"></span><sup>2</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>P</em><span class=\"xrefLink\" id=\"jumplink-tblfn12\"></span><a href=\"javascript:;\" reveal-id=\"tblfn12\" data-open=\"tblfn12\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>e</sup></a><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>N</em><span class=\"xrefLink\" id=\"jumplink-tblfn7\"></span><a href=\"javascript:;\" reveal-id=\"tblfn7\" data-open=\"tblfn7\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>a</sup></a><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>HR<span class=\"xrefLink\" id=\"jumplink-tblfn8\"></span><a href=\"javascript:;\" reveal-id=\"tblfn8\" data-open=\"tblfn8\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>b</sup></a><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>95% CI<span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th>I<span class=\"xrefLink\" id=\"jumplink-dyz017-B2\"></span><sup>2</sup><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th><th><em>P</em><span class=\"xrefLink\" id=\"jumplink-tblfn12\"></span><a href=\"javascript:;\" reveal-id=\"tblfn12\" data-open=\"tblfn12\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>e</sup></a><span aria-hidden=\"true\" style=\"display: none;\">\n", | |
| " . </span></th></tr></thead><tbody><tr><td>OP insecticides</td><td>131</td><td>0.78</td><td>(0.34–1.76)</td><td>2%</td><td>0.36</td><td>313</td><td>0.85</td><td>(0.56–1.29)</td><td>0%</td><td>0.83</td></tr><tr><td> Chlorpyrifos</td><td>46</td><td>1.08<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.68–1.70)</td><td>0%</td><td>0.58</td><td>97</td><td>0.93<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.66–1.32)</td><td>0%</td><td>0.73</td></tr><tr><td> Dichlorvos</td><td>40</td><td>1.10</td><td>(0.69–1.76)</td><td>0%</td><td>0.95</td><td>111</td><td>0.98</td><td>(0.70–1.37)</td><td>22%</td><td>0.28</td></tr><tr><td> Malathion</td><td>114</td><td>1.18</td><td>(0.66–2.10)</td><td>0%</td><td>0.64</td><td>269</td><td>0.95</td><td>(0.67–1.36)</td><td>0%</td><td>0.69</td></tr><tr><td> Parathion</td><td>83</td><td>1.24</td><td>(0.72–2.15)</td><td>0%</td><td>0.44</td><td>230</td><td>0.84</td><td>(0.57–1.24)</td><td>18%</td><td>0.30</td></tr><tr><td> Terbufos</td><td>35</td><td>1.33<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.80–2.20)</td><td>0%</td><td>0.70</td><td>55</td><td>1.01<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.69–1.49)</td><td>0%</td><td>0.64</td></tr><tr><td>Carbamate insecticides</td><td>115</td><td>1.03</td><td>(0.63–1.68)</td><td>0%</td><td>0.47</td><td>290</td><td>1.25</td><td>(0.89–1.75)</td><td>9%</td><td>0.33</td></tr><tr><td> Aldicarb</td><td>38</td><td>0.94</td><td>(0.56–1.56)</td><td>0%</td><td>0.79</td><td>113</td><td>0.91</td><td>(0.68–1.22)</td><td>0%</td><td>0.58</td></tr><tr><td> Carbaryl</td><td>67</td><td>1.27<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.66–2.43)</td><td>27%</td><td>0.24</td><td>152</td><td>1.11</td><td>(0.71–1.74)</td><td>47%</td><td>0.15</td></tr><tr><td> Carbofuran</td><td>26</td><td>0.91<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.52–1.59)</td><td>0%</td><td>0.94</td><td>57</td><td>1.21<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.83–1.78)</td><td>0%</td><td>0.70</td></tr><tr><td> Pirimicarb</td><td>58</td><td>0.84<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.41–1.71)</td><td>0%</td><td>0.96</td><td>185</td><td>1.01<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.70–1.46)</td><td>0%</td><td>0.68</td></tr><tr><td>OC insecticides</td><td>114</td><td>0.87</td><td>(0.54–1.40)</td><td>0%</td><td>0.82</td><td>290</td><td>1.03</td><td>(0.76–1.40)</td><td>0%</td><td>0.97</td></tr><tr><td> DDT</td><td>79</td><td>0.78</td><td>(0.45–1.37)</td><td>38%</td><td>0.20</td><td>230</td><td>0.96</td><td>(0.74–1.25)</td><td>0%</td><td>0.86</td></tr><tr><td> Lindane</td><td>78</td><td>0.92</td><td>(0.61–1.38)</td><td>0%</td><td>0.57</td><td>216</td><td>0.97</td><td>(0.74–1.28)</td><td>0%</td><td>0.89</td></tr><tr><td>Pyrethroid insecticides</td><td>81</td><td>1.16</td><td>(0.75–1.79)</td><td>0%</td><td>0.87</td><td>210</td><td>1.07</td><td>(0.79–1.46)</td><td>0%</td><td>0.72</td></tr><tr><td> Deltamethrin</td><td>46</td><td>1.09<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.64–1.87)</td><td>0%</td><td>0.77</td><td>135</td><td>0.93<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.69–1.24)</td><td>0%</td><td>0.97</td></tr><tr><td> Esfenvalerate</td><td>41</td><td>1.04<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.61–1.75)</td><td>0%</td><td>0.44</td><td>120</td><td>1.65</td><td>(0.61–4.41)</td><td>89%</td><td>0.00</td></tr><tr><td> Permethrin</td><td>60</td><td>0.79</td><td>(0.42–1.50)</td><td>26%</td><td>0.26</td><td>187</td><td>1.18</td><td>(0.86–1.63)</td><td>0%</td><td>0.61</td></tr><tr><td>(Phenyl) urea herbicides</td><td>81</td><td>1.09</td><td>(0.65–1.82)</td><td>0%</td><td>0.84</td><td>227</td><td>1.08</td><td>(0.79–1.47)</td><td>0%</td><td>0.65</td></tr><tr><td> Isoproturon</td><td>28</td><td>0.70<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.36–1.36)</td><td>0%</td><td>0.90</td><td>100</td><td>1.04<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.72–1.52)</td><td>0%</td><td>0.78</td></tr><tr><td> Linuron</td><td>79</td><td>1.11</td><td>(0.66–1.87)</td><td>0%</td><td>0.76</td><td>224</td><td>1.13</td><td>(0.81–1.57)</td><td>0%</td><td>0.78</td></tr><tr><td>Dicamba</td><td>73</td><td>0.81</td><td>(0.53–1.23)</td><td>0%</td><td>0.63</td><td>179</td><td>1.21</td><td>(0.93–1.59)</td><td>0%</td><td>0.92</td></tr><tr><td>Chloroacetanilides</td><td>78</td><td>1.00</td><td>(0.63–1.58)</td><td>0%</td><td>0.92</td><td>147</td><td>0.94</td><td>(0.71–1.25)</td><td>0%</td><td>0.88</td></tr><tr><td> Alachlor</td><td>43</td><td>0.86<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.47–1.56)</td><td>0%</td><td>0.96</td><td>78</td><td>1.06<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.73–1.54)</td><td>0%</td><td>0.94</td></tr><tr><td> Metolachlor</td><td>43</td><td>1.05<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.59–1.86)</td><td>0%</td><td>0.90</td><td>71</td><td>1.05<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.71–1.53)</td><td>0%</td><td>0.71</td></tr><tr><td>Dinitroaniline herbicides</td><td>57</td><td>0.99<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.56–1.74)</td><td>0%</td><td>0.71</td><td>95</td><td>0.82<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.42–1.61)</td><td>69%</td><td>0.07</td></tr><tr><td> Trifluralin</td><td>39</td><td>0.80<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.47–1.35)</td><td>0%</td><td>0.66</td><td>70</td><td>0.89<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.60–1.32)</td><td>0%</td><td>0.44</td></tr><tr><td>Glyphosate</td><td>105</td><td>0.79</td><td>(0.52–1.21)</td><td>0%</td><td>0.56</td><td>240</td><td>0.87</td><td>(0.66–1.15)</td><td>0%</td><td>0.95</td></tr><tr><td>Phenoxy herbicides</td><td>115</td><td>1.02</td><td>(0.60–1.75)</td><td>0%</td><td>0.95</td><td>257</td><td>0.77</td><td>(0.49–1.22)</td><td>43%</td><td>0.18</td></tr><tr><td> 2, 4-D</td><td>113</td><td>1.14</td><td>(0.67–1.96)</td><td>0%</td><td>0.91</td><td>250</td><td>0.90</td><td>(0.65–1.26)</td><td>0%</td><td>0.53</td></tr><tr><td> MCPA</td><td>60</td><td>1.21<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.53–2.80)</td><td>6%</td><td>0.30</td><td>174</td><td>0.69<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.29–1.64)</td><td>64%</td><td>0.10</td></tr><tr><td> MCPP</td><td>59</td><td>0.96<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.25–3.61)</td><td>58%</td><td>0.13</td><td>175</td><td>0.82<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.25–2.67)</td><td>82%</td><td>0.02</td></tr><tr><td>Thiocarbamate herbicides</td><td>88</td><td>0.81</td><td>(0.52–1.26)</td><td>0%</td><td>0.68</td><td>225</td><td>0.99</td><td>(0.73–1.34)</td><td>0%</td><td>0.80</td></tr><tr><td> Butylate</td><td>31</td><td>1.06<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.63–1.77)</td><td>0%</td><td>0.94</td><td>54</td><td>1.04<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.70–1.53)</td><td>0%</td><td>0.69</td></tr><tr><td> EPTC</td><td>49</td><td>0.86</td><td>(0.42–1.73)</td><td>51%</td><td>0.13</td><td>138</td><td>1.19</td><td>(0.90–1.59)</td><td>0%</td><td>0.87</td></tr><tr><td>Triazine herbicides</td><td>115</td><td>1.45</td><td>(0.62–3.39)</td><td>56%</td><td>0.10</td><td>246</td><td>0.82</td><td>(0.50–1.35)</td><td>56%</td><td>0.10</td></tr><tr><td> Atrazine</td><td>65</td><td>1.28<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.69–2.38)</td><td>0%</td><td>0.79</td><td>108</td><td>0.98<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.62–1.55)</td><td>0%</td><td>0.54</td></tr><tr><td> Simazine</td><td>23</td><td>0.91</td><td>(0.48–1.70)</td><td>0%</td><td>0.88</td><td>66</td><td>0.83</td><td>(0.52–1.32)</td><td>35%</td><td>0.22</td></tr><tr><td>Triazinone herbicides</td><td>86</td><td>0.85</td><td>(0.54–1.36)</td><td>0%</td><td>0.41</td><td>221</td><td>1.20</td><td>(0.73–1.97)</td><td>51%</td><td>0.13</td></tr><tr><td> Metribuzin</td><td>86</td><td>0.86</td><td>(0.54–1.36)</td><td>0%</td><td>0.41</td><td>221</td><td>1.20</td><td>(0.74–1.97)</td><td>51%</td><td>0.13</td></tr><tr><td>Dithiocarbamate fungicides</td><td>75</td><td>0.88</td><td>(0.52–1.49)</td><td>0%</td><td>0.98</td><td>229</td><td>1.11</td><td>(0.80–1.52)</td><td>0%</td><td>0.74</td></tr><tr><td> Mancozeb</td><td>71</td><td>0.80</td><td>(0.46–1.39)</td><td>0%</td><td>0.90</td><td>222</td><td>1.07</td><td>(0.78–1.48)</td><td>0%</td><td>0.64</td></tr><tr><td> Thiram</td><td>17</td><td>0.84<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.40–1.79)</td><td>0%</td><td>0.72</td><td>58</td><td>0.80<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.40–1.61)</td><td>60%</td><td>0.12</td></tr><tr><td>Phthalimide fungicides</td><td>71</td><td>0.73<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.37–1.44)</td><td>0%</td><td>0.84</td><td>216</td><td>1.05</td><td>(0.71–1.54)</td><td>0%</td><td>0.81</td></tr><tr><td> Captafol</td><td>62</td><td>1.11<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.51–2.42)</td><td>10%</td><td>0.29</td><td>192</td><td>1.13<span class=\"xrefLink\" id=\"jumplink-tblfn9\"></span><a href=\"javascript:;\" reveal-id=\"tblfn9\" data-open=\"tblfn9\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>c</sup></a></td><td>(0.76–1.68)</td><td>0%</td><td>0.45</td></tr><tr><td> Captan</td><td>36</td><td>0.90</td><td>(0.47–1.72)</td><td>0%</td><td>0.59</td><td>97</td><td>0.73</td><td>(0.39–1.37)</td><td>48%</td><td>0.15</td></tr><tr><td>Arsenicals</td><td>17</td><td></td><td></td><td></td><td></td><td>65</td><td>0.91<span class=\"xrefLink\" id=\"jumplink-tblfn10\"></span><a href=\"javascript:;\" reveal-id=\"tblfn10\" data-open=\"tblfn10\" class=\"link link-ref link-reveal xref-fn js-xref-fn\" data-google-interstitial=\"false\"><sup>d</sup></a></td><td>(0.59–1.40)</td><td>0%</td><td>0.84</td></tr><tr><td colspan=\"11\"><hr></td></tr></tbody></table></div><div class=\"table-wrap-foot\"><span id=\"fn-tblfn5\"></span><div content-id=\"tblfn5\" class=\"footnote\"><span class=\"fn\"><p class=\"chapter-para\">AGRICAN: Cox regression adjusted for: sex, livestock, retirement status, number of selected types of crops for which pesticide treatment personally applied.</p></span></div><span id=\"fn-tblfn6\"></span><div content-id=\"tblfn6\" class=\"footnote\"><span class=\"fn\"><p class=\"chapter-para\">CNAP: Cox regression adjusted for: sex, livestock, dichlorvos, aldicarb, lindane, DDT, deltametrin, mancozeb, linuron, glyphosate.</p></span></div><span id=\"fn-tblfn7\"></span><div content-id=\"tblfn7\" class=\"footnote\"><span class=\"fn\"><p class=\"chapter-para\">AHS: Cox regression adjusted for: sex, state, livestock, terbufos, lindane, DDT, permethrin, dicamba, parathion, carbaryl.</p></span></div><span id=\"fn-tblfn8\"></span><div content-id=\"tblfn8\" class=\"footnote\"><span class=\"fn\"><p class=\"chapter-para\">mHR estimates for DLBCL in association with MCPA and MCPP not available because statistical models did not converge.</p></span></div><span id=\"fn-tblfn9\"></span><div content-id=\"tblfn9\" class=\"footnote\"><span class=\"fn\"><p class=\"chapter-para\">mHR estimate for FL in association with arsenicals not available because an estimate could be computed in only one (AGRICAN) of three cohorts. OC, organochlorine; OP, organophosphate; I<sup>2</sup> (I-squared, variation in meta-estimate attributable to heterogeneity).</p></span></div><span id=\"fn-tblfn10\"></span><div content-id=\"tblfn10\" class=\"footnote\"><span class=\"fn\"><p class=\"chapter-para\"><sup>a</sup>Number of cancer cases.</p></span></div><span id=\"fn-tblfn11\"></span><div content-id=\"tblfn11\" class=\"footnote\"><span class=\"fn\"><p class=\"chapter-para\"><sup>b</sup>Hazard ratio: random effects meta-analysis (fully adjusted models).</p></span></div><span id=\"fn-tblfn12\"></span><div content-id=\"tblfn12\" class=\"footnote\"><span class=\"fn\"><p class=\"chapter-para\"><sup>c</sup>Meta-analysis based on AGRICAN and CNAP only. For esfenvalerate, AHS contributed to mHR of NHL and multiple myeloma.</p></span></div><span id=\"fn-tblfn13\"></span><div content-id=\"tblfn13\" class=\"footnote\"><span class=\"fn\"><p class=\"chapter-para\"><sup>d</sup>Meta-analysis based on AGRICAN and AHS only.</p></span></div><span id=\"fn-tblfn14\"></span><div content-id=\"tblfn14\" class=\"footnote\"><span class=\"fn\"><p class=\"chapter-para\"><sup>e</sup><em>P</em>-value for heterogeneity.</p></span></div></div><div class=\"\n", | |
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| "<iframe id=\"_hjSafeContext_36119723\" title=\"_hjSafeContext\" tabindex=\"-1\" aria-hidden=\"true\" src=\"about:blank\" style=\"display: none !important; width: 1px !important; height: 1px !important; opacity: 0 !important; pointer-events: none !important;\"></iframe></body></html>\"\"\"\n", | |
| ")" | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": 3, | |
| "id": "78b6db9d-1f9c-44e1-b8e4-5c037e54f696", | |
| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T21:23:45.593175Z", | |
| "iopub.status.busy": "2024-04-16T21:23:45.592443Z", | |
| "iopub.status.idle": "2024-04-16T21:23:45.597802Z", | |
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| "shell.execute_reply.started": "2024-04-16T21:23:45.593156Z" | |
| } | |
| }, | |
| "outputs": [], | |
| "source": [ | |
| "def transform_data(df_):\n", | |
| " return (\n", | |
| " df_\n", | |
| " .set_index((\"Unnamed: 0_level_0\",\"Unnamed: 0_level_1\"))\n", | |
| " .stack(0)\n", | |
| " .reset_index()\n", | |
| " .rename({('Unnamed: 0_level_0', 'Unnamed: 0_level_1'):\"Insecticides\",\n", | |
| " \"level_1\":\"cancer_type\"}, axis=1)\n", | |
| " .sort_index()\n", | |
| " )" | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": 4, | |
| "id": "428a1191-da54-45d9-ab9a-2ed5a4a4af11", | |
| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T21:23:46.124150Z", | |
| "iopub.status.busy": "2024-04-16T21:23:46.123785Z", | |
| "iopub.status.idle": "2024-04-16T21:23:46.128045Z", | |
| "shell.execute_reply": "2024-04-16T21:23:46.127429Z", | |
| "shell.execute_reply.started": "2024-04-16T21:23:46.124129Z" | |
| } | |
| }, | |
| "outputs": [], | |
| "source": [ | |
| "def clean_hrb(df_):\n", | |
| " df_[\"HRb\"] = pd.to_numeric(df_.HRb.str.replace('[^\\d\\.]', '', regex=True)).astype(\"float\")\n", | |
| " return df_\n", | |
| " " | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": null, | |
| "id": "5690f7cd-c9b3-4c8e-9a34-749c4d116ea3", | |
| "metadata": {}, | |
| "outputs": [], | |
| "source": [] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": 5, | |
| "id": "343f1c6a-9093-440a-9e89-d78948e4b703", | |
| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T21:23:46.848835Z", | |
| "iopub.status.busy": "2024-04-16T21:23:46.848204Z", | |
| "iopub.status.idle": "2024-04-16T21:23:47.009149Z", | |
| "shell.execute_reply": "2024-04-16T21:23:47.008857Z", | |
| "shell.execute_reply.started": "2024-04-16T21:23:46.848815Z" | |
| } | |
| }, | |
| "outputs": [ | |
| { | |
| "data": { | |
| "text/html": [ | |
| "<div>\n", | |
| "<style scoped>\n", | |
| " .dataframe tbody tr th:only-of-type {\n", | |
| " vertical-align: middle;\n", | |
| " }\n", | |
| "\n", | |
| " .dataframe tbody tr th {\n", | |
| " vertical-align: top;\n", | |
| " }\n", | |
| "\n", | |
| " .dataframe thead th {\n", | |
| " text-align: right;\n", | |
| " }\n", | |
| "</style>\n", | |
| "<table border=\"1\" class=\"dataframe\">\n", | |
| " <thead>\n", | |
| " <tr style=\"text-align: right;\">\n", | |
| " <th></th>\n", | |
| " <th>index</th>\n", | |
| " <th>Insecticides</th>\n", | |
| " <th>cancer_type</th>\n", | |
| " <th>Na</th>\n", | |
| " <th>HRb</th>\n", | |
| " <th>95% CI</th>\n", | |
| " <th>I2</th>\n", | |
| " <th>Pe</th>\n", | |
| " </tr>\n", | |
| " </thead>\n", | |
| " <tbody>\n", | |
| " <tr>\n", | |
| " <th>0</th>\n", | |
| " <td>0</td>\n", | |
| " <td>OP Insecticides</td>\n", | |
| " <td>Chronic lymphocytic leukaemia/small lymphocyti...</td>\n", | |
| " <td>318.0</td>\n", | |
| " <td>1.03</td>\n", | |
| " <td>(0.64–1.65)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.65</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>1</th>\n", | |
| " <td>1</td>\n", | |
| " <td>OP Insecticides</td>\n", | |
| " <td>Diffuse large B-cell lymphoma (DLBCL)</td>\n", | |
| " <td>256.0</td>\n", | |
| " <td>0.90</td>\n", | |
| " <td>(0.58–1.39)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.71</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>2</th>\n", | |
| " <td>2</td>\n", | |
| " <td>OP Insecticides</td>\n", | |
| " <td>Non-Hodgkin lymphoid malignancies (NHL)</td>\n", | |
| " <td>1417.0</td>\n", | |
| " <td>0.90</td>\n", | |
| " <td>(0.75–1.09)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.56</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>3</th>\n", | |
| " <td>3</td>\n", | |
| " <td>Chlorpyrifos</td>\n", | |
| " <td>Chronic lymphocytic leukaemia/small lymphocyti...</td>\n", | |
| " <td>106.0</td>\n", | |
| " <td>1.05d</td>\n", | |
| " <td>(0.77–1.42)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.84</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>4</th>\n", | |
| " <td>4</td>\n", | |
| " <td>Chlorpyrifos</td>\n", | |
| " <td>Diffuse large B-cell lymphoma (DLBCL)</td>\n", | |
| " <td>86.0</td>\n", | |
| " <td>0.99d</td>\n", | |
| " <td>(0.72–1.36)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.76</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>...</th>\n", | |
| " <td>...</td>\n", | |
| " <td>...</td>\n", | |
| " <td>...</td>\n", | |
| " <td>...</td>\n", | |
| " <td>...</td>\n", | |
| " <td>...</td>\n", | |
| " <td>...</td>\n", | |
| " <td>...</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>230</th>\n", | |
| " <td>89</td>\n", | |
| " <td>Captafol</td>\n", | |
| " <td>Multiple myeloma/plasma-cell leukaemia (MM)</td>\n", | |
| " <td>192.0</td>\n", | |
| " <td>1.13c</td>\n", | |
| " <td>(0.76–1.68)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.45</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>231</th>\n", | |
| " <td>90</td>\n", | |
| " <td>Captan</td>\n", | |
| " <td>Follicular lymphoma (FL)</td>\n", | |
| " <td>36.0</td>\n", | |
| " <td>0.90</td>\n", | |
| " <td>(0.47–1.72)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.59</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>232</th>\n", | |
| " <td>91</td>\n", | |
| " <td>Captan</td>\n", | |
| " <td>Multiple myeloma/plasma-cell leukaemia (MM)</td>\n", | |
| " <td>97.0</td>\n", | |
| " <td>0.73</td>\n", | |
| " <td>(0.39–1.37)</td>\n", | |
| " <td>48%</td>\n", | |
| " <td>0.15</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>233</th>\n", | |
| " <td>92</td>\n", | |
| " <td>Arsenicals</td>\n", | |
| " <td>Follicular lymphoma (FL)</td>\n", | |
| " <td>17.0</td>\n", | |
| " <td>NaN</td>\n", | |
| " <td>NaN</td>\n", | |
| " <td>NaN</td>\n", | |
| " <td>NaN</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>234</th>\n", | |
| " <td>93</td>\n", | |
| " <td>Arsenicals</td>\n", | |
| " <td>Multiple myeloma/plasma-cell leukaemia (MM)</td>\n", | |
| " <td>65.0</td>\n", | |
| " <td>0.91d</td>\n", | |
| " <td>(0.59–1.40)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.84</td>\n", | |
| " </tr>\n", | |
| " </tbody>\n", | |
| "</table>\n", | |
| "<p>235 rows × 8 columns</p>\n", | |
| "</div>" | |
| ], | |
| "text/plain": [ | |
| " index Insecticides \\\n", | |
| "0 0 OP Insecticides \n", | |
| "1 1 OP Insecticides \n", | |
| "2 2 OP Insecticides \n", | |
| "3 3 Chlorpyrifos \n", | |
| "4 4 Chlorpyrifos \n", | |
| ".. ... ... \n", | |
| "230 89 Captafol \n", | |
| "231 90 Captan \n", | |
| "232 91 Captan \n", | |
| "233 92 Arsenicals \n", | |
| "234 93 Arsenicals \n", | |
| "\n", | |
| " cancer_type Na HRb \\\n", | |
| "0 Chronic lymphocytic leukaemia/small lymphocyti... 318.0 1.03 \n", | |
| "1 Diffuse large B-cell lymphoma (DLBCL) 256.0 0.90 \n", | |
| "2 Non-Hodgkin lymphoid malignancies (NHL) 1417.0 0.90 \n", | |
| "3 Chronic lymphocytic leukaemia/small lymphocyti... 106.0 1.05d \n", | |
| "4 Diffuse large B-cell lymphoma (DLBCL) 86.0 0.99d \n", | |
| ".. ... ... ... \n", | |
| "230 Multiple myeloma/plasma-cell leukaemia (MM) 192.0 1.13c \n", | |
| "231 Follicular lymphoma (FL) 36.0 0.90 \n", | |
| "232 Multiple myeloma/plasma-cell leukaemia (MM) 97.0 0.73 \n", | |
| "233 Follicular lymphoma (FL) 17.0 NaN \n", | |
| "234 Multiple myeloma/plasma-cell leukaemia (MM) 65.0 0.91d \n", | |
| "\n", | |
| " 95% CI I2 Pe \n", | |
| "0 (0.64–1.65) 0% 0.65 \n", | |
| "1 (0.58–1.39) 0% 0.71 \n", | |
| "2 (0.75–1.09) 0% 0.56 \n", | |
| "3 (0.77–1.42) 0% 0.84 \n", | |
| "4 (0.72–1.36) 0% 0.76 \n", | |
| ".. ... ... ... \n", | |
| "230 (0.76–1.68) 0% 0.45 \n", | |
| "231 (0.47–1.72) 0% 0.59 \n", | |
| "232 (0.39–1.37) 48% 0.15 \n", | |
| "233 NaN NaN NaN \n", | |
| "234 (0.59–1.40) 0% 0.84 \n", | |
| "\n", | |
| "[235 rows x 8 columns]" | |
| ] | |
| }, | |
| "execution_count": 5, | |
| "metadata": {}, | |
| "output_type": "execute_result" | |
| } | |
| ], | |
| "source": [ | |
| "pd.concat(\n", | |
| " [pd.read_html(html_content)[0].pipe(transform_data),\n", | |
| " pd.read_html(html_content)[2].pipe(transform_data)]\n", | |
| ").reset_index()" | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": 6, | |
| "id": "07f99d8a-9717-430c-b05a-9018aad9bf8f", | |
| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T21:23:47.868139Z", | |
| "iopub.status.busy": "2024-04-16T21:23:47.867643Z", | |
| "iopub.status.idle": "2024-04-16T21:23:47.874168Z", | |
| "shell.execute_reply": "2024-04-16T21:23:47.873433Z", | |
| "shell.execute_reply.started": "2024-04-16T21:23:47.868118Z" | |
| } | |
| }, | |
| "outputs": [], | |
| "source": [ | |
| "def ci_string_to_numbers(df_):\n", | |
| " \"\"\"\n", | |
| " Take a string of confidence interval and add\n", | |
| " 3 columns to df: upper_bound, lower_bound, reject_null ( True if parameter is significative)\n", | |
| " \"\"\"\n", | |
| " return (\n", | |
| " df_.assign(ci_lower_bound = lambda df_ : df_.loc[:,\"95% CI\"].str.split(\"–\").str[0].str.replace(\"(\",\"\").astype(\"float\"),\n", | |
| " ci_upper_bound = lambda df_ : df_.loc[:,\"95% CI\"].str.split(\"–\").str[1].str.replace(\")\",\"\").astype(\"float\"),\n", | |
| " )\n", | |
| " .assign(reject_null = lambda x: (x.ci_lower_bound>=1 ) | (x.ci_upper_bound<=1 ) )\n", | |
| " )\n", | |
| " " | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": 7, | |
| "id": "b7f8abd5-64bb-46ad-ae41-3125c62549bb", | |
| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T21:23:48.515963Z", | |
| "iopub.status.busy": "2024-04-16T21:23:48.515682Z", | |
| "iopub.status.idle": "2024-04-16T21:23:48.624172Z", | |
| "shell.execute_reply": "2024-04-16T21:23:48.623850Z", | |
| "shell.execute_reply.started": "2024-04-16T21:23:48.515947Z" | |
| } | |
| }, | |
| "outputs": [], | |
| "source": [ | |
| "df_intermediate = pd.concat(\n", | |
| " [pd.read_html(html_content)[0].pipe(transform_data),\n", | |
| " pd.read_html(html_content)[2].pipe(transform_data)]\n", | |
| ").reset_index().pipe(ci_string_to_numbers).pipe(clean_hrb)" | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": 8, | |
| "id": "4d503e1e-6d39-465e-b315-c8f49dedc380", | |
| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T21:23:49.793020Z", | |
| "iopub.status.busy": "2024-04-16T21:23:49.792285Z", | |
| "iopub.status.idle": "2024-04-16T21:23:49.798536Z", | |
| "shell.execute_reply": "2024-04-16T21:23:49.797773Z", | |
| "shell.execute_reply.started": "2024-04-16T21:23:49.792995Z" | |
| } | |
| }, | |
| "outputs": [ | |
| { | |
| "data": { | |
| "text/plain": [ | |
| "0.9878879310344828" | |
| ] | |
| }, | |
| "execution_count": 8, | |
| "metadata": {}, | |
| "output_type": "execute_result" | |
| } | |
| ], | |
| "source": [ | |
| "df_intermediate.HRb.mean()" | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": 9, | |
| "id": "549c64c7-f40f-428e-a159-701ddb465b46", | |
| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T21:23:50.912422Z", | |
| "iopub.status.busy": "2024-04-16T21:23:50.911456Z", | |
| "iopub.status.idle": "2024-04-16T21:23:50.925828Z", | |
| "shell.execute_reply": "2024-04-16T21:23:50.925188Z", | |
| "shell.execute_reply.started": "2024-04-16T21:23:50.912392Z" | |
| } | |
| }, | |
| "outputs": [ | |
| { | |
| "data": { | |
| "text/plain": [ | |
| "0.02127659574468085" | |
| ] | |
| }, | |
| "execution_count": 9, | |
| "metadata": {}, | |
| "output_type": "execute_result" | |
| } | |
| ], | |
| "source": [ | |
| "df_intermediate.reject_null.mean()" | |
| ] | |
| }, | |
| { | |
| "cell_type": "markdown", | |
| "id": "d05eaf10-3a8b-4239-b452-37a56c5126b7", | |
| "metadata": {}, | |
| "source": [ | |
| "Que 2.12% d'hypothèse nulle rejettée ! L'espérance est de 5%..." | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": 10, | |
| "id": "3627371a-5eef-4664-b180-760d2e5e1ea8", | |
| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T21:24:10.085422Z", | |
| "iopub.status.busy": "2024-04-16T21:24:10.084094Z", | |
| "iopub.status.idle": "2024-04-16T21:24:13.595502Z", | |
| "shell.execute_reply": "2024-04-16T21:24:13.595214Z", | |
| "shell.execute_reply.started": "2024-04-16T21:24:10.085356Z" | |
| } | |
| }, | |
| "outputs": [], | |
| "source": [ | |
| "import numpy as np\n", | |
| "uniform_result_list = []\n", | |
| "for a in range(10**6):\n", | |
| " uniform_result_list.append((\n", | |
| " np.random.uniform(0,1,235)<=0.05).sum()<=5)" | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": 11, | |
| "id": "9d4f1e90-e8c6-46fb-8f13-b8e8603bd599", | |
| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T21:24:13.596203Z", | |
| "iopub.status.busy": "2024-04-16T21:24:13.596138Z", | |
| "iopub.status.idle": "2024-04-16T21:24:13.765126Z", | |
| "shell.execute_reply": "2024-04-16T21:24:13.764891Z", | |
| "shell.execute_reply.started": "2024-04-16T21:24:13.596196Z" | |
| } | |
| }, | |
| "outputs": [ | |
| { | |
| "data": { | |
| "text/plain": [ | |
| "0.021089" | |
| ] | |
| }, | |
| "execution_count": 11, | |
| "metadata": {}, | |
| "output_type": "execute_result" | |
| } | |
| ], | |
| "source": [ | |
| "pd.Series(uniform_result_list).mean()" | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": 12, | |
| "id": "7df528b0-d913-415d-9329-e07bcfedf51e", | |
| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T21:24:22.318712Z", | |
| "iopub.status.busy": "2024-04-16T21:24:22.316813Z", | |
| "iopub.status.idle": "2024-04-16T21:24:22.759211Z", | |
| "shell.execute_reply": "2024-04-16T21:24:22.758908Z", | |
| "shell.execute_reply.started": "2024-04-16T21:24:22.318613Z" | |
| } | |
| }, | |
| "outputs": [], | |
| "source": [ | |
| "from scipy.stats import norm\n", | |
| "def ci_to_p_value(lower_bound, upper_bound, null_hypothesis, confidence_level=0.95):\n", | |
| " \"\"\"\n", | |
| " Calculate the p-value from a confidence interval.\n", | |
| " \n", | |
| " Parameters:\n", | |
| " - lower_bound (float): The lower bound of the confidence interval.\n", | |
| " - upper_bound (float): The upper bound of the confidence interval.\n", | |
| " - null_hypothesis (float): The value under the null hypothesis for testing.\n", | |
| " - confidence_level (float): The confidence level of the interval (default is 0.95).\n", | |
| " \n", | |
| " Returns:\n", | |
| " - float: The p-value calculated from the confidence interval.\n", | |
| " \"\"\"\n", | |
| " # Calculate the z-score for the given confidence level (for a two-tailed test)\n", | |
| " z_star = norm.ppf((1 + confidence_level) / 2)\n", | |
| " \n", | |
| " # Calculate the point estimate, assuming it is the midpoint of the confidence interval\n", | |
| " point_estimate = (upper_bound + lower_bound) / 2\n", | |
| " \n", | |
| " # Calculate the standard error from the confidence interval and the z-score\n", | |
| " standard_error = (upper_bound - lower_bound) / (2 * z_star)\n", | |
| " \n", | |
| " # Calculate the test statistic\n", | |
| " test_statistic = (point_estimate - null_hypothesis) / standard_error\n", | |
| " \n", | |
| " # Calculate the p-value based on the test statistic\n", | |
| " # For a two-tailed test\n", | |
| " p_value = 2 * (1 - norm.cdf(abs(test_statistic)))\n", | |
| " \n", | |
| " return p_value\n" | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": 13, | |
| "id": "4de1ffe8-27d6-464f-90eb-c6b93470f715", | |
| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T21:24:24.140662Z", | |
| "iopub.status.busy": "2024-04-16T21:24:24.140276Z", | |
| "iopub.status.idle": "2024-04-16T21:24:24.193105Z", | |
| "shell.execute_reply": "2024-04-16T21:24:24.192636Z", | |
| "shell.execute_reply.started": "2024-04-16T21:24:24.140642Z" | |
| } | |
| }, | |
| "outputs": [], | |
| "source": [ | |
| "df_intermediate[\"p_value\"] = df_intermediate.apply(lambda x: ci_to_p_value(x[\"ci_lower_bound\"],\n", | |
| " x[\"ci_upper_bound\"],\n", | |
| " 1, confidence_level=.95), axis=1)\n" | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": 14, | |
| "id": "4f856fd2-c95f-43f1-b890-d2a94a79236a", | |
| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T21:24:24.976886Z", | |
| "iopub.status.busy": "2024-04-16T21:24:24.976566Z", | |
| "iopub.status.idle": "2024-04-16T21:24:25.006758Z", | |
| "shell.execute_reply": "2024-04-16T21:24:25.004361Z", | |
| "shell.execute_reply.started": "2024-04-16T21:24:24.976869Z" | |
| } | |
| }, | |
| "outputs": [ | |
| { | |
| "data": { | |
| "text/html": [ | |
| "<div>\n", | |
| "<style scoped>\n", | |
| " .dataframe tbody tr th:only-of-type {\n", | |
| " vertical-align: middle;\n", | |
| " }\n", | |
| "\n", | |
| " .dataframe tbody tr th {\n", | |
| " vertical-align: top;\n", | |
| " }\n", | |
| "\n", | |
| " .dataframe thead th {\n", | |
| " text-align: right;\n", | |
| " }\n", | |
| "</style>\n", | |
| "<table border=\"1\" class=\"dataframe\">\n", | |
| " <thead>\n", | |
| " <tr style=\"text-align: right;\">\n", | |
| " <th></th>\n", | |
| " <th>index</th>\n", | |
| " <th>Insecticides</th>\n", | |
| " <th>cancer_type</th>\n", | |
| " <th>Na</th>\n", | |
| " <th>HRb</th>\n", | |
| " <th>95% CI</th>\n", | |
| " <th>I2</th>\n", | |
| " <th>Pe</th>\n", | |
| " <th>ci_lower_bound</th>\n", | |
| " <th>ci_upper_bound</th>\n", | |
| " <th>reject_null</th>\n", | |
| " <th>p_value</th>\n", | |
| " </tr>\n", | |
| " </thead>\n", | |
| " <tbody>\n", | |
| " <tr>\n", | |
| " <th>86</th>\n", | |
| " <td>86</td>\n", | |
| " <td>Phenoxy herbicides</td>\n", | |
| " <td>Non-Hodgkin lymphoid malignancies (NHL)</td>\n", | |
| " <td>1204.0</td>\n", | |
| " <td>0.81</td>\n", | |
| " <td>(0.67–0.98)</td>\n", | |
| " <td>19%</td>\n", | |
| " <td>0.29</td>\n", | |
| " <td>0.67</td>\n", | |
| " <td>0.98</td>\n", | |
| " <td>True</td>\n", | |
| " <td>0.026907</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>45</th>\n", | |
| " <td>45</td>\n", | |
| " <td>Deltamethrin</td>\n", | |
| " <td>Chronic lymphocytic leukaemia/small lymphocyti...</td>\n", | |
| " <td>148.0</td>\n", | |
| " <td>1.48</td>\n", | |
| " <td>(1.06–2.07)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.35</td>\n", | |
| " <td>1.06</td>\n", | |
| " <td>2.07</td>\n", | |
| " <td>True</td>\n", | |
| " <td>0.028320</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>35</th>\n", | |
| " <td>35</td>\n", | |
| " <td>OC insecticides</td>\n", | |
| " <td>Non-Hodgkin lymphoid malignancies (NHL)</td>\n", | |
| " <td>1258.0</td>\n", | |
| " <td>0.86</td>\n", | |
| " <td>(0.74–0.99)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.77</td>\n", | |
| " <td>0.74</td>\n", | |
| " <td>0.99</td>\n", | |
| " <td>True</td>\n", | |
| " <td>0.034280</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>17</th>\n", | |
| " <td>17</td>\n", | |
| " <td>Terbufos</td>\n", | |
| " <td>Non-Hodgkin lymphoid malignancies (NHL)</td>\n", | |
| " <td>300.0</td>\n", | |
| " <td>1.18</td>\n", | |
| " <td>(1.00–1.39)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.53</td>\n", | |
| " <td>1.00</td>\n", | |
| " <td>1.39</td>\n", | |
| " <td>True</td>\n", | |
| " <td>0.050000</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>82</th>\n", | |
| " <td>82</td>\n", | |
| " <td>Glyphosate</td>\n", | |
| " <td>Diffuse large B-cell lymphoma (DLBCL)</td>\n", | |
| " <td>221.0</td>\n", | |
| " <td>1.36</td>\n", | |
| " <td>(1.00–1.85)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.48</td>\n", | |
| " <td>1.00</td>\n", | |
| " <td>1.85</td>\n", | |
| " <td>True</td>\n", | |
| " <td>0.050000</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>41</th>\n", | |
| " <td>41</td>\n", | |
| " <td>Lindane</td>\n", | |
| " <td>Non-Hodgkin lymphoid malignancies (NHL)</td>\n", | |
| " <td>953.0</td>\n", | |
| " <td>0.89</td>\n", | |
| " <td>(0.78–1.01)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.87</td>\n", | |
| " <td>0.78</td>\n", | |
| " <td>1.01</td>\n", | |
| " <td>False</td>\n", | |
| " <td>0.073529</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>107</th>\n", | |
| " <td>107</td>\n", | |
| " <td>Triazine herbicides</td>\n", | |
| " <td>Non-Hodgkin lymphoid malignancies (NHL)</td>\n", | |
| " <td>1165.0</td>\n", | |
| " <td>0.87</td>\n", | |
| " <td>(0.74–1.02)</td>\n", | |
| " <td>8%</td>\n", | |
| " <td>0.34</td>\n", | |
| " <td>0.74</td>\n", | |
| " <td>1.02</td>\n", | |
| " <td>False</td>\n", | |
| " <td>0.092963</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>15</th>\n", | |
| " <td>15</td>\n", | |
| " <td>Terbufos</td>\n", | |
| " <td>Chronic lymphocytic leukaemia/small lymphocyti...</td>\n", | |
| " <td>76.0</td>\n", | |
| " <td>1.28</td>\n", | |
| " <td>(0.92–1.79)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>1.00</td>\n", | |
| " <td>0.92</td>\n", | |
| " <td>1.79</td>\n", | |
| " <td>False</td>\n", | |
| " <td>0.109707</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>174</th>\n", | |
| " <td>33</td>\n", | |
| " <td>Esfenvalerate</td>\n", | |
| " <td>Multiple myeloma/plasma-cell leukaemia (MM)</td>\n", | |
| " <td>120.0</td>\n", | |
| " <td>1.65</td>\n", | |
| " <td>(0.61–4.41)</td>\n", | |
| " <td>89%</td>\n", | |
| " <td>0.00</td>\n", | |
| " <td>0.61</td>\n", | |
| " <td>4.41</td>\n", | |
| " <td>False</td>\n", | |
| " <td>0.119315</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>184</th>\n", | |
| " <td>43</td>\n", | |
| " <td>Dicamba</td>\n", | |
| " <td>Multiple myeloma/plasma-cell leukaemia (MM)</td>\n", | |
| " <td>179.0</td>\n", | |
| " <td>1.21</td>\n", | |
| " <td>(0.93–1.59)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.92</td>\n", | |
| " <td>0.93</td>\n", | |
| " <td>1.59</td>\n", | |
| " <td>False</td>\n", | |
| " <td>0.122536</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>42</th>\n", | |
| " <td>42</td>\n", | |
| " <td>Pyrethroid insecticides</td>\n", | |
| " <td>Chronic lymphocytic leukaemia/small lymphocyti...</td>\n", | |
| " <td>211.0</td>\n", | |
| " <td>1.29</td>\n", | |
| " <td>(0.90–1.84)</td>\n", | |
| " <td>15%</td>\n", | |
| " <td>0.31</td>\n", | |
| " <td>0.90</td>\n", | |
| " <td>1.84</td>\n", | |
| " <td>False</td>\n", | |
| " <td>0.122843</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>154</th>\n", | |
| " <td>13</td>\n", | |
| " <td>Carbamate insecticides</td>\n", | |
| " <td>Multiple myeloma/plasma-cell leukaemia (MM)</td>\n", | |
| " <td>290.0</td>\n", | |
| " <td>1.25</td>\n", | |
| " <td>(0.89–1.75)</td>\n", | |
| " <td>9%</td>\n", | |
| " <td>0.33</td>\n", | |
| " <td>0.89</td>\n", | |
| " <td>1.75</td>\n", | |
| " <td>False</td>\n", | |
| " <td>0.144681</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>51</th>\n", | |
| " <td>51</td>\n", | |
| " <td>Permethrin</td>\n", | |
| " <td>Chronic lymphocytic leukaemia/small lymphocyti...</td>\n", | |
| " <td>182.0</td>\n", | |
| " <td>1.30</td>\n", | |
| " <td>(0.85–2.00)</td>\n", | |
| " <td>25%</td>\n", | |
| " <td>0.26</td>\n", | |
| " <td>0.85</td>\n", | |
| " <td>2.00</td>\n", | |
| " <td>False</td>\n", | |
| " <td>0.147430</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>211</th>\n", | |
| " <td>70</td>\n", | |
| " <td>Triazine herbicides</td>\n", | |
| " <td>Follicular lymphoma (FL)</td>\n", | |
| " <td>115.0</td>\n", | |
| " <td>1.45</td>\n", | |
| " <td>(0.62–3.39)</td>\n", | |
| " <td>56%</td>\n", | |
| " <td>0.10</td>\n", | |
| " <td>0.62</td>\n", | |
| " <td>3.39</td>\n", | |
| " <td>False</td>\n", | |
| " <td>0.154965</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>89</th>\n", | |
| " <td>89</td>\n", | |
| " <td>2, 4-D</td>\n", | |
| " <td>Non-Hodgkin lymphoid malignancies (NHL)</td>\n", | |
| " <td>1167.0</td>\n", | |
| " <td>0.88</td>\n", | |
| " <td>(0.75–1.04)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.87</td>\n", | |
| " <td>0.75</td>\n", | |
| " <td>1.04</td>\n", | |
| " <td>False</td>\n", | |
| " <td>0.155816</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>151</th>\n", | |
| " <td>10</td>\n", | |
| " <td>Terbufos</td>\n", | |
| " <td>Follicular lymphoma (FL)</td>\n", | |
| " <td>35.0</td>\n", | |
| " <td>1.33</td>\n", | |
| " <td>(0.80–2.20)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.70</td>\n", | |
| " <td>0.80</td>\n", | |
| " <td>2.20</td>\n", | |
| " <td>False</td>\n", | |
| " <td>0.161521</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>210</th>\n", | |
| " <td>69</td>\n", | |
| " <td>EPTC</td>\n", | |
| " <td>Multiple myeloma/plasma-cell leukaemia (MM)</td>\n", | |
| " <td>138.0</td>\n", | |
| " <td>1.19</td>\n", | |
| " <td>(0.90–1.59)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.87</td>\n", | |
| " <td>0.90</td>\n", | |
| " <td>1.59</td>\n", | |
| " <td>False</td>\n", | |
| " <td>0.163965</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>8</th>\n", | |
| " <td>8</td>\n", | |
| " <td>Dichlorvos</td>\n", | |
| " <td>Non-Hodgkin lymphoid malignancies (NHL)</td>\n", | |
| " <td>523.0</td>\n", | |
| " <td>1.10</td>\n", | |
| " <td>(0.95–1.27)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.72</td>\n", | |
| " <td>0.95</td>\n", | |
| " <td>1.27</td>\n", | |
| " <td>False</td>\n", | |
| " <td>0.177827</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>23</th>\n", | |
| " <td>23</td>\n", | |
| " <td>Aldicarb</td>\n", | |
| " <td>Non-Hodgkin lymphoid malignancies (NHL)</td>\n", | |
| " <td>526.0</td>\n", | |
| " <td>1.09</td>\n", | |
| " <td>(0.95–1.26)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.67</td>\n", | |
| " <td>0.95</td>\n", | |
| " <td>1.26</td>\n", | |
| " <td>False</td>\n", | |
| " <td>0.184271</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>114</th>\n", | |
| " <td>114</td>\n", | |
| " <td>Triazinone herbicides</td>\n", | |
| " <td>Chronic lymphocytic leukaemia/small lymphocyti...</td>\n", | |
| " <td>215.0</td>\n", | |
| " <td>1.22</td>\n", | |
| " <td>(0.84–1.77)</td>\n", | |
| " <td>21%</td>\n", | |
| " <td>0.28</td>\n", | |
| " <td>0.84</td>\n", | |
| " <td>1.77</td>\n", | |
| " <td>False</td>\n", | |
| " <td>0.198594</td>\n", | |
| " </tr>\n", | |
| " </tbody>\n", | |
| "</table>\n", | |
| "</div>" | |
| ], | |
| "text/plain": [ | |
| " index Insecticides \\\n", | |
| "86 86 Phenoxy herbicides \n", | |
| "45 45 Deltamethrin \n", | |
| "35 35 OC insecticides \n", | |
| "17 17 Terbufos \n", | |
| "82 82 Glyphosate \n", | |
| "41 41 Lindane \n", | |
| "107 107 Triazine herbicides \n", | |
| "15 15 Terbufos \n", | |
| "174 33 Esfenvalerate \n", | |
| "184 43 Dicamba \n", | |
| "42 42 Pyrethroid insecticides \n", | |
| "154 13 Carbamate insecticides \n", | |
| "51 51 Permethrin \n", | |
| "211 70 Triazine herbicides \n", | |
| "89 89 2, 4-D \n", | |
| "151 10 Terbufos \n", | |
| "210 69 EPTC \n", | |
| "8 8 Dichlorvos \n", | |
| "23 23 Aldicarb \n", | |
| "114 114 Triazinone herbicides \n", | |
| "\n", | |
| " cancer_type Na HRb \\\n", | |
| "86 Non-Hodgkin lymphoid malignancies (NHL) 1204.0 0.81 \n", | |
| "45 Chronic lymphocytic leukaemia/small lymphocyti... 148.0 1.48 \n", | |
| "35 Non-Hodgkin lymphoid malignancies (NHL) 1258.0 0.86 \n", | |
| "17 Non-Hodgkin lymphoid malignancies (NHL) 300.0 1.18 \n", | |
| "82 Diffuse large B-cell lymphoma (DLBCL) 221.0 1.36 \n", | |
| "41 Non-Hodgkin lymphoid malignancies (NHL) 953.0 0.89 \n", | |
| "107 Non-Hodgkin lymphoid malignancies (NHL) 1165.0 0.87 \n", | |
| "15 Chronic lymphocytic leukaemia/small lymphocyti... 76.0 1.28 \n", | |
| "174 Multiple myeloma/plasma-cell leukaemia (MM) 120.0 1.65 \n", | |
| "184 Multiple myeloma/plasma-cell leukaemia (MM) 179.0 1.21 \n", | |
| "42 Chronic lymphocytic leukaemia/small lymphocyti... 211.0 1.29 \n", | |
| "154 Multiple myeloma/plasma-cell leukaemia (MM) 290.0 1.25 \n", | |
| "51 Chronic lymphocytic leukaemia/small lymphocyti... 182.0 1.30 \n", | |
| "211 Follicular lymphoma (FL) 115.0 1.45 \n", | |
| "89 Non-Hodgkin lymphoid malignancies (NHL) 1167.0 0.88 \n", | |
| "151 Follicular lymphoma (FL) 35.0 1.33 \n", | |
| "210 Multiple myeloma/plasma-cell leukaemia (MM) 138.0 1.19 \n", | |
| "8 Non-Hodgkin lymphoid malignancies (NHL) 523.0 1.10 \n", | |
| "23 Non-Hodgkin lymphoid malignancies (NHL) 526.0 1.09 \n", | |
| "114 Chronic lymphocytic leukaemia/small lymphocyti... 215.0 1.22 \n", | |
| "\n", | |
| " 95% CI I2 Pe ci_lower_bound ci_upper_bound reject_null \\\n", | |
| "86 (0.67–0.98) 19% 0.29 0.67 0.98 True \n", | |
| "45 (1.06–2.07) 0% 0.35 1.06 2.07 True \n", | |
| "35 (0.74–0.99) 0% 0.77 0.74 0.99 True \n", | |
| "17 (1.00–1.39) 0% 0.53 1.00 1.39 True \n", | |
| "82 (1.00–1.85) 0% 0.48 1.00 1.85 True \n", | |
| "41 (0.78–1.01) 0% 0.87 0.78 1.01 False \n", | |
| "107 (0.74–1.02) 8% 0.34 0.74 1.02 False \n", | |
| "15 (0.92–1.79) 0% 1.00 0.92 1.79 False \n", | |
| "174 (0.61–4.41) 89% 0.00 0.61 4.41 False \n", | |
| "184 (0.93–1.59) 0% 0.92 0.93 1.59 False \n", | |
| "42 (0.90–1.84) 15% 0.31 0.90 1.84 False \n", | |
| "154 (0.89–1.75) 9% 0.33 0.89 1.75 False \n", | |
| "51 (0.85–2.00) 25% 0.26 0.85 2.00 False \n", | |
| "211 (0.62–3.39) 56% 0.10 0.62 3.39 False \n", | |
| "89 (0.75–1.04) 0% 0.87 0.75 1.04 False \n", | |
| "151 (0.80–2.20) 0% 0.70 0.80 2.20 False \n", | |
| "210 (0.90–1.59) 0% 0.87 0.90 1.59 False \n", | |
| "8 (0.95–1.27) 0% 0.72 0.95 1.27 False \n", | |
| "23 (0.95–1.26) 0% 0.67 0.95 1.26 False \n", | |
| "114 (0.84–1.77) 21% 0.28 0.84 1.77 False \n", | |
| "\n", | |
| " p_value \n", | |
| "86 0.026907 \n", | |
| "45 0.028320 \n", | |
| "35 0.034280 \n", | |
| "17 0.050000 \n", | |
| "82 0.050000 \n", | |
| "41 0.073529 \n", | |
| "107 0.092963 \n", | |
| "15 0.109707 \n", | |
| "174 0.119315 \n", | |
| "184 0.122536 \n", | |
| "42 0.122843 \n", | |
| "154 0.144681 \n", | |
| "51 0.147430 \n", | |
| "211 0.154965 \n", | |
| "89 0.155816 \n", | |
| "151 0.161521 \n", | |
| "210 0.163965 \n", | |
| "8 0.177827 \n", | |
| "23 0.184271 \n", | |
| "114 0.198594 " | |
| ] | |
| }, | |
| "execution_count": 14, | |
| "metadata": {}, | |
| "output_type": "execute_result" | |
| } | |
| ], | |
| "source": [ | |
| "df_intermediate.sort_values(\"p_value\").dropna().head(20)" | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": 15, | |
| "id": "232251b3-1cc8-4b6b-ab2f-f2d108290ea6", | |
| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T21:24:49.116372Z", | |
| "iopub.status.busy": "2024-04-16T21:24:49.114577Z", | |
| "iopub.status.idle": "2024-04-16T21:24:49.127510Z", | |
| "shell.execute_reply": "2024-04-16T21:24:49.126763Z", | |
| "shell.execute_reply.started": "2024-04-16T21:24:49.116310Z" | |
| } | |
| }, | |
| "outputs": [ | |
| { | |
| "data": { | |
| "text/plain": [ | |
| "46.4" | |
| ] | |
| }, | |
| "execution_count": 15, | |
| "metadata": {}, | |
| "output_type": "execute_result" | |
| } | |
| ], | |
| "source": [ | |
| "232/5" | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": 16, | |
| "id": "499e8228-3db9-4cea-9eaf-a3bc7eeeb523", | |
| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T21:24:49.878194Z", | |
| "iopub.status.busy": "2024-04-16T21:24:49.877851Z", | |
| "iopub.status.idle": "2024-04-16T21:24:49.887608Z", | |
| "shell.execute_reply": "2024-04-16T21:24:49.886820Z", | |
| "shell.execute_reply.started": "2024-04-16T21:24:49.878173Z" | |
| } | |
| }, | |
| "outputs": [ | |
| { | |
| "data": { | |
| "text/plain": [ | |
| "21" | |
| ] | |
| }, | |
| "execution_count": 16, | |
| "metadata": {}, | |
| "output_type": "execute_result" | |
| } | |
| ], | |
| "source": [ | |
| "(df_intermediate[\"p_value\"].dropna()<=1/5).sum()" | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": 17, | |
| "id": "cf233fce-9071-4f09-92f4-2d6eea243066", | |
| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T21:24:50.422393Z", | |
| "iopub.status.busy": "2024-04-16T21:24:50.421896Z", | |
| "iopub.status.idle": "2024-04-16T21:24:50.427514Z", | |
| "shell.execute_reply": "2024-04-16T21:24:50.426898Z", | |
| "shell.execute_reply.started": "2024-04-16T21:24:50.422372Z" | |
| } | |
| }, | |
| "outputs": [ | |
| { | |
| "data": { | |
| "text/plain": [ | |
| "0.09051724137931035" | |
| ] | |
| }, | |
| "execution_count": 17, | |
| "metadata": {}, | |
| "output_type": "execute_result" | |
| } | |
| ], | |
| "source": [ | |
| "(df_intermediate[\"p_value\"].dropna()<=1/5).mean()" | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": 18, | |
| "id": "dab94217-4d5c-47ba-a962-d03cafaaab4f", | |
| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T21:24:51.676507Z", | |
| "iopub.status.busy": "2024-04-16T21:24:51.676174Z", | |
| "iopub.status.idle": "2024-04-16T21:25:26.824326Z", | |
| "shell.execute_reply": "2024-04-16T21:25:26.823425Z", | |
| "shell.execute_reply.started": "2024-04-16T21:24:51.676489Z" | |
| } | |
| }, | |
| "outputs": [], | |
| "source": [ | |
| "import numpy as np\n", | |
| "p_value_below_one_fith = []\n", | |
| "for a in range(10**7):\n", | |
| " p_value_below_one_fith.append((\n", | |
| " np.random.uniform(0,1,235)<=1/5).sum())" | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": 19, | |
| "id": "f79fbf04-d2f1-4b58-8472-ebc6ff147af4", | |
| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T21:25:26.825849Z", | |
| "iopub.status.busy": "2024-04-16T21:25:26.825623Z", | |
| "iopub.status.idle": "2024-04-16T21:25:35.198460Z", | |
| "shell.execute_reply": "2024-04-16T21:25:35.196116Z", | |
| "shell.execute_reply.started": "2024-04-16T21:25:26.825813Z" | |
| } | |
| }, | |
| "outputs": [ | |
| { | |
| "data": { | |
| "text/plain": [ | |
| "1.4e-06" | |
| ] | |
| }, | |
| "execution_count": 19, | |
| "metadata": {}, | |
| "output_type": "execute_result" | |
| } | |
| ], | |
| "source": [ | |
| "(pd.Series(p_value_below_one_fith)<21).mean() # Probabilité que seule 21 p-values sur 235 soit en dessous de 0.2" | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": 391, | |
| "id": "9338e44a-182f-4097-8175-cf279f6c30a0", | |
| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T20:21:40.833465Z", | |
| "iopub.status.busy": "2024-04-16T20:21:40.830785Z", | |
| "iopub.status.idle": "2024-04-16T20:21:40.992545Z", | |
| "shell.execute_reply": "2024-04-16T20:21:40.992106Z", | |
| "shell.execute_reply.started": "2024-04-16T20:21:40.833397Z" | |
| } | |
| }, | |
| "outputs": [ | |
| { | |
| "data": { | |
| "text/plain": [ | |
| "Text(0, 0.5, 'Number of obs')" | |
| ] | |
| }, | |
| "execution_count": 391, | |
| "metadata": {}, | |
| "output_type": "execute_result" | |
| }, | |
| { | |
| "data": { | |
| "image/png": 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", | |
| "text/plain": [ | |
| "<Figure size 640x480 with 1 Axes>" | |
| ] | |
| }, | |
| "metadata": {}, | |
| "output_type": "display_data" | |
| } | |
| ], | |
| "source": [ | |
| "bin_number = 6\n", | |
| "df_intermediate[\"p_value\"].dropna().hist(bins=[a/bin_number for a in range(0,bin_number+1)])\n", | |
| "plt.hlines(len(df_intermediate.p_value.dropna())/6,0,1,colors=\"r\", linestyles=\"--\")\n", | |
| "plt.xlim(0,1)\n", | |
| "plt.xlabel(\"p-values\")\n", | |
| "plt.ylabel(\"Number of obs\")" | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": 395, | |
| "id": "5a47dd7a-ca22-4061-8c2b-99274f72858e", | |
| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T20:35:33.650432Z", | |
| "iopub.status.busy": "2024-04-16T20:35:33.649599Z", | |
| "iopub.status.idle": "2024-04-16T20:35:33.670100Z", | |
| "shell.execute_reply": "2024-04-16T20:35:33.669387Z", | |
| "shell.execute_reply.started": "2024-04-16T20:35:33.650399Z" | |
| } | |
| }, | |
| "outputs": [], | |
| "source": [ | |
| "from scipy.stats import norm\n", | |
| "def ci_to_se(lower_bound, upper_bound, confidence_level=0.95):\n", | |
| " \"\"\"\n", | |
| " Calculate the p-value from a confidence interval.\n", | |
| " \n", | |
| " Parameters:\n", | |
| " - lower_bound (float): The lower bound of the confidence interval.\n", | |
| " - upper_bound (float): The upper bound of the confidence interval.\n", | |
| " - null_hypothesis (float): The value under the null hypothesis for testing.\n", | |
| " - confidence_level (float): The confidence level of the interval (default is 0.95).\n", | |
| " \n", | |
| " Returns:\n", | |
| " - float: The SE calculated from the confidence interval.\n", | |
| " \"\"\"\n", | |
| " # Calculate the z-score for the given confidence level (for a two-tailed test)\n", | |
| " z_star = norm.ppf((1 + confidence_level) / 2)\n", | |
| " \n", | |
| " # Calculate the point estimate, assuming it is the midpoint of the confidence interval\n", | |
| " point_estimate = (upper_bound + lower_bound) / 2\n", | |
| " \n", | |
| " # Calculate the standard error from the confidence interval and the z-score\n", | |
| " standard_error = (upper_bound - lower_bound) / (2 * z_star)\n", | |
| " \n", | |
| " return standard_error\n" | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": 423, | |
| "id": "1127fad6-27e3-4530-a67a-1909d7991531", | |
| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T20:45:25.864923Z", | |
| "iopub.status.busy": "2024-04-16T20:45:25.863246Z", | |
| "iopub.status.idle": "2024-04-16T20:45:25.923822Z", | |
| "shell.execute_reply": "2024-04-16T20:45:25.922660Z", | |
| "shell.execute_reply.started": "2024-04-16T20:45:25.864859Z" | |
| } | |
| }, | |
| "outputs": [], | |
| "source": [ | |
| "df_intermediate[\"se\"] = df_intermediate.apply(lambda x: ci_to_se(x[\"ci_lower_bound\"],\n", | |
| " x[\"ci_upper_bound\"],\n", | |
| " confidence_level=.95), axis=1)\n" | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": 424, | |
| "id": "608a37f1-5841-4d40-bce2-47a6c1d4ba63", | |
| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T20:45:26.066777Z", | |
| "iopub.status.busy": "2024-04-16T20:45:26.066210Z", | |
| "iopub.status.idle": "2024-04-16T20:45:26.088123Z", | |
| "shell.execute_reply": "2024-04-16T20:45:26.087828Z", | |
| "shell.execute_reply.started": "2024-04-16T20:45:26.066744Z" | |
| } | |
| }, | |
| "outputs": [ | |
| { | |
| "data": { | |
| "text/html": [ | |
| "<div>\n", | |
| "<style scoped>\n", | |
| " .dataframe tbody tr th:only-of-type {\n", | |
| " vertical-align: middle;\n", | |
| " }\n", | |
| "\n", | |
| " .dataframe tbody tr th {\n", | |
| " vertical-align: top;\n", | |
| " }\n", | |
| "\n", | |
| " .dataframe thead th {\n", | |
| " text-align: right;\n", | |
| " }\n", | |
| "</style>\n", | |
| "<table border=\"1\" class=\"dataframe\">\n", | |
| " <thead>\n", | |
| " <tr style=\"text-align: right;\">\n", | |
| " <th></th>\n", | |
| " <th>index</th>\n", | |
| " <th>Insecticides</th>\n", | |
| " <th>cancer_type</th>\n", | |
| " <th>Na</th>\n", | |
| " <th>HRb</th>\n", | |
| " <th>95% CI</th>\n", | |
| " <th>I2</th>\n", | |
| " <th>Pe</th>\n", | |
| " <th>ci_lower_bound</th>\n", | |
| " <th>ci_upper_bound</th>\n", | |
| " <th>reject_null</th>\n", | |
| " <th>se</th>\n", | |
| " </tr>\n", | |
| " </thead>\n", | |
| " <tbody>\n", | |
| " <tr>\n", | |
| " <th>0</th>\n", | |
| " <td>0</td>\n", | |
| " <td>OP Insecticides</td>\n", | |
| " <td>Chronic lymphocytic leukaemia/small lymphocyti...</td>\n", | |
| " <td>318.0</td>\n", | |
| " <td>1.03</td>\n", | |
| " <td>(0.64–1.65)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.65</td>\n", | |
| " <td>0.64</td>\n", | |
| " <td>1.65</td>\n", | |
| " <td>False</td>\n", | |
| " <td>0.257658</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>1</th>\n", | |
| " <td>1</td>\n", | |
| " <td>OP Insecticides</td>\n", | |
| " <td>Diffuse large B-cell lymphoma (DLBCL)</td>\n", | |
| " <td>256.0</td>\n", | |
| " <td>0.90</td>\n", | |
| " <td>(0.58–1.39)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.71</td>\n", | |
| " <td>0.58</td>\n", | |
| " <td>1.39</td>\n", | |
| " <td>False</td>\n", | |
| " <td>0.206636</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>2</th>\n", | |
| " <td>2</td>\n", | |
| " <td>OP Insecticides</td>\n", | |
| " <td>Non-Hodgkin lymphoid malignancies (NHL)</td>\n", | |
| " <td>1417.0</td>\n", | |
| " <td>0.90</td>\n", | |
| " <td>(0.75–1.09)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.56</td>\n", | |
| " <td>0.75</td>\n", | |
| " <td>1.09</td>\n", | |
| " <td>False</td>\n", | |
| " <td>0.086736</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>3</th>\n", | |
| " <td>3</td>\n", | |
| " <td>Chlorpyrifos</td>\n", | |
| " <td>Chronic lymphocytic leukaemia/small lymphocyti...</td>\n", | |
| " <td>106.0</td>\n", | |
| " <td>1.05</td>\n", | |
| " <td>(0.77–1.42)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.84</td>\n", | |
| " <td>0.77</td>\n", | |
| " <td>1.42</td>\n", | |
| " <td>False</td>\n", | |
| " <td>0.165819</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>4</th>\n", | |
| " <td>4</td>\n", | |
| " <td>Chlorpyrifos</td>\n", | |
| " <td>Diffuse large B-cell lymphoma (DLBCL)</td>\n", | |
| " <td>86.0</td>\n", | |
| " <td>0.99</td>\n", | |
| " <td>(0.72–1.36)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.76</td>\n", | |
| " <td>0.72</td>\n", | |
| " <td>1.36</td>\n", | |
| " <td>False</td>\n", | |
| " <td>0.163268</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>...</th>\n", | |
| " <td>...</td>\n", | |
| " <td>...</td>\n", | |
| " <td>...</td>\n", | |
| " <td>...</td>\n", | |
| " <td>...</td>\n", | |
| " <td>...</td>\n", | |
| " <td>...</td>\n", | |
| " <td>...</td>\n", | |
| " <td>...</td>\n", | |
| " <td>...</td>\n", | |
| " <td>...</td>\n", | |
| " <td>...</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>230</th>\n", | |
| " <td>89</td>\n", | |
| " <td>Captafol</td>\n", | |
| " <td>Multiple myeloma/plasma-cell leukaemia (MM)</td>\n", | |
| " <td>192.0</td>\n", | |
| " <td>1.13</td>\n", | |
| " <td>(0.76–1.68)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.45</td>\n", | |
| " <td>0.76</td>\n", | |
| " <td>1.68</td>\n", | |
| " <td>False</td>\n", | |
| " <td>0.234698</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>231</th>\n", | |
| " <td>90</td>\n", | |
| " <td>Captan</td>\n", | |
| " <td>Follicular lymphoma (FL)</td>\n", | |
| " <td>36.0</td>\n", | |
| " <td>0.90</td>\n", | |
| " <td>(0.47–1.72)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.59</td>\n", | |
| " <td>0.47</td>\n", | |
| " <td>1.72</td>\n", | |
| " <td>False</td>\n", | |
| " <td>0.318883</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>232</th>\n", | |
| " <td>91</td>\n", | |
| " <td>Captan</td>\n", | |
| " <td>Multiple myeloma/plasma-cell leukaemia (MM)</td>\n", | |
| " <td>97.0</td>\n", | |
| " <td>0.73</td>\n", | |
| " <td>(0.39–1.37)</td>\n", | |
| " <td>48%</td>\n", | |
| " <td>0.15</td>\n", | |
| " <td>0.39</td>\n", | |
| " <td>1.37</td>\n", | |
| " <td>False</td>\n", | |
| " <td>0.250005</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>233</th>\n", | |
| " <td>92</td>\n", | |
| " <td>Arsenicals</td>\n", | |
| " <td>Follicular lymphoma (FL)</td>\n", | |
| " <td>17.0</td>\n", | |
| " <td>NaN</td>\n", | |
| " <td>NaN</td>\n", | |
| " <td>NaN</td>\n", | |
| " <td>NaN</td>\n", | |
| " <td>NaN</td>\n", | |
| " <td>NaN</td>\n", | |
| " <td>False</td>\n", | |
| " <td>NaN</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>234</th>\n", | |
| " <td>93</td>\n", | |
| " <td>Arsenicals</td>\n", | |
| " <td>Multiple myeloma/plasma-cell leukaemia (MM)</td>\n", | |
| " <td>65.0</td>\n", | |
| " <td>0.91</td>\n", | |
| " <td>(0.59–1.40)</td>\n", | |
| " <td>0%</td>\n", | |
| " <td>0.84</td>\n", | |
| " <td>0.59</td>\n", | |
| " <td>1.40</td>\n", | |
| " <td>False</td>\n", | |
| " <td>0.206636</td>\n", | |
| " </tr>\n", | |
| " </tbody>\n", | |
| "</table>\n", | |
| "<p>235 rows × 12 columns</p>\n", | |
| "</div>" | |
| ], | |
| "text/plain": [ | |
| " index Insecticides \\\n", | |
| "0 0 OP Insecticides \n", | |
| "1 1 OP Insecticides \n", | |
| "2 2 OP Insecticides \n", | |
| "3 3 Chlorpyrifos \n", | |
| "4 4 Chlorpyrifos \n", | |
| ".. ... ... \n", | |
| "230 89 Captafol \n", | |
| "231 90 Captan \n", | |
| "232 91 Captan \n", | |
| "233 92 Arsenicals \n", | |
| "234 93 Arsenicals \n", | |
| "\n", | |
| " cancer_type Na HRb \\\n", | |
| "0 Chronic lymphocytic leukaemia/small lymphocyti... 318.0 1.03 \n", | |
| "1 Diffuse large B-cell lymphoma (DLBCL) 256.0 0.90 \n", | |
| "2 Non-Hodgkin lymphoid malignancies (NHL) 1417.0 0.90 \n", | |
| "3 Chronic lymphocytic leukaemia/small lymphocyti... 106.0 1.05 \n", | |
| "4 Diffuse large B-cell lymphoma (DLBCL) 86.0 0.99 \n", | |
| ".. ... ... ... \n", | |
| "230 Multiple myeloma/plasma-cell leukaemia (MM) 192.0 1.13 \n", | |
| "231 Follicular lymphoma (FL) 36.0 0.90 \n", | |
| "232 Multiple myeloma/plasma-cell leukaemia (MM) 97.0 0.73 \n", | |
| "233 Follicular lymphoma (FL) 17.0 NaN \n", | |
| "234 Multiple myeloma/plasma-cell leukaemia (MM) 65.0 0.91 \n", | |
| "\n", | |
| " 95% CI I2 Pe ci_lower_bound ci_upper_bound reject_null \\\n", | |
| "0 (0.64–1.65) 0% 0.65 0.64 1.65 False \n", | |
| "1 (0.58–1.39) 0% 0.71 0.58 1.39 False \n", | |
| "2 (0.75–1.09) 0% 0.56 0.75 1.09 False \n", | |
| "3 (0.77–1.42) 0% 0.84 0.77 1.42 False \n", | |
| "4 (0.72–1.36) 0% 0.76 0.72 1.36 False \n", | |
| ".. ... ... ... ... ... ... \n", | |
| "230 (0.76–1.68) 0% 0.45 0.76 1.68 False \n", | |
| "231 (0.47–1.72) 0% 0.59 0.47 1.72 False \n", | |
| "232 (0.39–1.37) 48% 0.15 0.39 1.37 False \n", | |
| "233 NaN NaN NaN NaN NaN False \n", | |
| "234 (0.59–1.40) 0% 0.84 0.59 1.40 False \n", | |
| "\n", | |
| " se \n", | |
| "0 0.257658 \n", | |
| "1 0.206636 \n", | |
| "2 0.086736 \n", | |
| "3 0.165819 \n", | |
| "4 0.163268 \n", | |
| ".. ... \n", | |
| "230 0.234698 \n", | |
| "231 0.318883 \n", | |
| "232 0.250005 \n", | |
| "233 NaN \n", | |
| "234 0.206636 \n", | |
| "\n", | |
| "[235 rows x 12 columns]" | |
| ] | |
| }, | |
| "execution_count": 424, | |
| "metadata": {}, | |
| "output_type": "execute_result" | |
| } | |
| ], | |
| "source": [ | |
| "df_intermediate" | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": 453, | |
| "id": "8435f55f-8ab9-4e1b-b65f-6100e5094c27", | |
| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T21:10:03.297768Z", | |
| "iopub.status.busy": "2024-04-16T21:10:03.295984Z", | |
| "iopub.status.idle": "2024-04-16T21:10:03.382596Z", | |
| "shell.execute_reply": "2024-04-16T21:10:03.382164Z", | |
| "shell.execute_reply.started": "2024-04-16T21:10:03.297690Z" | |
| } | |
| }, | |
| "outputs": [ | |
| { | |
| "data": { | |
| "application/vnd.plotly.v1+json": { | |
| "config": { | |
| "plotlyServerURL": "https://plot.ly" | |
| }, | |
| "data": [ | |
| { | |
| "customdata": [ | |
| [ | |
| "OP Insecticides", | |
| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.5735970028454058 | |
| ], | |
| [ | |
| "OP Insecticides", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.9421313829266011 | |
| ], | |
| [ | |
| "OP Insecticides", | |
| "Non-Hodgkin lymphoid malignancies (NHL)", | |
| 0.35635334533943563 | |
| ], | |
| [ | |
| "Chlorpyrifos", | |
| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.5667039071548723 | |
| ], | |
| [ | |
| "Chlorpyrifos", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.8064599171794242 | |
| ], | |
| [ | |
| "Chlorpyrifos", | |
| "Non-Hodgkin lymphoid malignancies (NHL)", | |
| 0.9461160242354929 | |
| ], | |
| [ | |
| "Dichlorvos", | |
| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.4890930884974378 | |
| ], | |
| [ | |
| "Dichlorvos", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.9759447991043757 | |
| ], | |
| [ | |
| "Dichlorvos", | |
| "Non-Hodgkin lymphoid malignancies (NHL)", | |
| 0.17782722277498086 | |
| ], | |
| [ | |
| "Malathion", | |
| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.37298672609047223 | |
| ], | |
| [ | |
| "Malathion", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.5135491452916947 | |
| ], | |
| [ | |
| "Malathion", | |
| "Non-Hodgkin lymphoid malignancies (NHL)", | |
| 0.9082136798756777 | |
| ], | |
| [ | |
| "Parathion", | |
| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.7794814522504068 | |
| ], | |
| [ | |
| "Parathion", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.8627001630338427 | |
| ], | |
| [ | |
| "Parathion", | |
| "Non-Hodgkin lymphoid malignancies (NHL)", | |
| 0.6012129232590431 | |
| ], | |
| [ | |
| "Terbufos", | |
| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.10970714239558799 | |
| ], | |
| [ | |
| "Terbufos", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.46414736333288964 | |
| ], | |
| [ | |
| "Carbamate insecticides", | |
| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.5368898819161616 | |
| ], | |
| [ | |
| "Carbamate insecticides", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.23960351133683666 | |
| ], | |
| [ | |
| "Carbamate insecticides", | |
| "Non-Hodgkin lymphoid malignancies (NHL)", | |
| 0.4245781624343432 | |
| ], | |
| [ | |
| "Aldicarb", | |
| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.2564943349878246 | |
| ], | |
| [ | |
| "Aldicarb", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.6761684885982651 | |
| ], | |
| [ | |
| "Aldicarb", | |
| "Non-Hodgkin lymphoid malignancies (NHL)", | |
| 0.18427143756126907 | |
| ], | |
| [ | |
| "Carbaryl", | |
| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.8763856131242733 | |
| ], | |
| [ | |
| "Carbaryl", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.5446428878311684 | |
| ], | |
| [ | |
| "Carbaryl", | |
| "Non-Hodgkin lymphoid malignancies (NHL)", | |
| 0.6113559989995789 | |
| ], | |
| [ | |
| "Carbofuran", | |
| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.4531886541216408 | |
| ], | |
| [ | |
| "Carbofuran", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.6241402702064651 | |
| ], | |
| [ | |
| "Carbofuran", | |
| "Non-Hodgkin lymphoid malignancies (NHL)", | |
| 0.8276053778616714 | |
| ], | |
| [ | |
| "Pirimicarb", | |
| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.27076041336889967 | |
| ], | |
| [ | |
| "Pirimicarb", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.23960351133683622 | |
| ], | |
| [ | |
| "Pirimicarb", | |
| "Non-Hodgkin lymphoid malignancies (NHL)", | |
| 0.29944328081933747 | |
| ], | |
| [ | |
| "OC insecticides", | |
| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.44311574577906754 | |
| ], | |
| [ | |
| "OC insecticides", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.4196411373942781 | |
| ], | |
| [ | |
| "DDT", | |
| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.7715369901704823 | |
| ], | |
| [ | |
| "DDT", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.37674732170732006 | |
| ], | |
| [ | |
| "DDT", | |
| "Non-Hodgkin lymphoid malignancies (NHL)", | |
| 0.20116573937784477 | |
| ], | |
| [ | |
| "Lindane", | |
| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.527225851487807 | |
| ], | |
| [ | |
| "Lindane", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.9495876204321327 | |
| ], | |
| [ | |
| "Lindane", | |
| "Non-Hodgkin lymphoid malignancies (NHL)", | |
| 0.07352912500653375 | |
| ], | |
| [ | |
| "Pyrethroid insecticides", | |
| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.1228428179320824 | |
| ], | |
| [ | |
| "Pyrethroid insecticides", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.849564647661968 | |
| ], | |
| [ | |
| "Pyrethroid insecticides", | |
| "Non-Hodgkin lymphoid malignancies (NHL)", | |
| 0.5430119393131188 | |
| ], | |
| [ | |
| "Deltamethrin", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.8870591720758265 | |
| ], | |
| [ | |
| "Deltamethrin", | |
| "Non-Hodgkin lymphoid malignancies (NHL)", | |
| 0.5643043022909366 | |
| ], | |
| [ | |
| "Esfenvalerate", | |
| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.21344397508247193 | |
| ], | |
| [ | |
| "Esfenvalerate", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.6023646226407555 | |
| ], | |
| [ | |
| "Esfenvalerate", | |
| "Non-Hodgkin lymphoid malignancies (NHL)", | |
| 0.2762117112037088 | |
| ], | |
| [ | |
| "Permethrin", | |
| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.1474300327169602 | |
| ], | |
| [ | |
| "Permethrin", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.7731706878049169 | |
| ], | |
| [ | |
| "Permethrin", | |
| "Non-Hodgkin lymphoid malignancies (NHL)", | |
| 0.7132511280466416 | |
| ], | |
| [ | |
| "(Phenyl) urea herbicides", | |
| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.5025301882106923 | |
| ], | |
| [ | |
| "(Phenyl) urea herbicides", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.5565395451002915 | |
| ], | |
| [ | |
| "(Phenyl) urea herbicides", | |
| "Non-Hodgkin lymphoid malignancies (NHL)", | |
| 0.6012129232590417 | |
| ], | |
| [ | |
| "Isoproturon", | |
| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.2591239648471364 | |
| ], | |
| [ | |
| "Isoproturon", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.7746584105170125 | |
| ], | |
| [ | |
| "Isoproturon", | |
| "Non-Hodgkin lymphoid malignancies (NHL)", | |
| 0.6548683235562145 | |
| ], | |
| [ | |
| "Linuron", | |
| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.5704709818657523 | |
| ], | |
| [ | |
| "Linuron", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 1 | |
| ], | |
| [ | |
| "Linuron", | |
| "Non-Hodgkin lymphoid malignancies (NHL)", | |
| 0.41964113739427766 | |
| ], | |
| [ | |
| "Dicamba", | |
| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.5430119393131188 | |
| ], | |
| [ | |
| "Dicamba", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.9734993656950734 | |
| ], | |
| [ | |
| "Dicamba", | |
| "Non-Hodgkin lymphoid malignancies (NHL)", | |
| 0.5430119393131188 | |
| ], | |
| [ | |
| "Chloroacetanilides", | |
| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.9300677631390781 | |
| ], | |
| [ | |
| "Chloroacetanilides", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.4536173596242694 | |
| ], | |
| [ | |
| "Chloroacetanilides", | |
| "Non-Hodgkin lymphoid malignancies (NHL)", | |
| 0.9421313829266029 | |
| ], | |
| [ | |
| "Alachlor", | |
| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.6173576996772472 | |
| ], | |
| [ | |
| "Alachlor", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.6241402702064647 | |
| ], | |
| [ | |
| "Alachlor", | |
| "Non-Hodgkin lymphoid malignancies (NHL)", | |
| 0.8176380002432033 | |
| ], | |
| [ | |
| "Metolachlor", | |
| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.6788177909592323 | |
| ], | |
| [ | |
| "Metolachlor", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.8801599445471282 | |
| ], | |
| [ | |
| "Metolachlor", | |
| "Non-Hodgkin lymphoid malignancies (NHL)", | |
| 0.952639209461297 | |
| ], | |
| [ | |
| "Dinitroaniline herbicides", | |
| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.4733370790796583 | |
| ], | |
| [ | |
| "Dinitroaniline herbicides", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.8423903099264585 | |
| ], | |
| [ | |
| "Dinitroaniline herbicides", | |
| "Non-Hodgkin lymphoid malignancies (NHL)", | |
| 0.5643043022909369 | |
| ], | |
| [ | |
| "Trifluralin", | |
| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.9806954023036503 | |
| ], | |
| [ | |
| "Trifluralin", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.8665857076653847 | |
| ], | |
| [ | |
| "Trifluralin", | |
| "Non-Hodgkin lymphoid malignancies (NHL)", | |
| 0.8723668779032552 | |
| ], | |
| [ | |
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| 0.8030127424313347 | |
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| [ | |
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| [ | |
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| 0.8227605060027636 | |
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| [ | |
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| 0.7938391660329831 | |
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| [ | |
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| 1 | |
| ], | |
| [ | |
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| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.5754864565302427 | |
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| [ | |
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| [ | |
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| 0.62132407359784 | |
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| [ | |
| "MCPA", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| null | |
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| [ | |
| "MCPA", | |
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| [ | |
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| "Chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL)", | |
| 0.444554469094006 | |
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| [ | |
| "MCPP", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| null | |
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| [ | |
| "MCPP", | |
| "Non-Hodgkin lymphoid malignancies (NHL)", | |
| 0.8717714371566967 | |
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| [ | |
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| [ | |
| "Thiocarbamate herbicides", | |
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| [ | |
| "Thiocarbamate herbicides", | |
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| [ | |
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| [ | |
| "Butylate", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
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| [ | |
| "Butylate", | |
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| [ | |
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| 0.40091704090096614 | |
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| [ | |
| "EPTC", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
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| [ | |
| "EPTC", | |
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| [ | |
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| 0.5135491452916943 | |
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| [ | |
| "Triazine herbicides", | |
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| 0.4572185939402662 | |
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| [ | |
| "Triazine herbicides", | |
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| [ | |
| "Atrazine", | |
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| 0.804280227088433 | |
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| [ | |
| "Atrazine", | |
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| [ | |
| "Atrazine", | |
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| [ | |
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| 0.6876517225839438 | |
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| [ | |
| "Simazine", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
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| [ | |
| "Simazine", | |
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| [ | |
| "Triazinone herbicides", | |
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| 0.19859394929363594 | |
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| [ | |
| "Triazinone herbicides", | |
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| [ | |
| "Triazinone herbicides", | |
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| [ | |
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| 0.19859394929363594 | |
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| [ | |
| "Metribuzin", | |
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| [ | |
| "Metribuzin", | |
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| [ | |
| "Dithiocarbamate fungicides", | |
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| 0.5135491452916947 | |
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| [ | |
| "Dithiocarbamate fungicides", | |
| "Diffuse large B-cell lymphoma (DLBCL)", | |
| 0.927921777331342 | |
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| [ | |
| "Dithiocarbamate fungicides", | |
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| [ | |
| "Mancozeb", | |
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| 0.7519089802661969 | |
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| [ | |
| "Mancozeb", | |
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| [ | |
| "Mancozeb", | |
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| [ | |
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| 0.925640113922565 | |
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| [ | |
| "Thiram", | |
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| 0.5135491452916947 | |
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| [ | |
| "Thiram", | |
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| [ | |
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| [ | |
| "Phthalimide fungicides", | |
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| [ | |
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| [ | |
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| [ | |
| "Captafol", | |
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| [ | |
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| [ | |
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| [ | |
| "Captan", | |
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| [ | |
| "Captan", | |
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| [ | |
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| [ | |
| "Arsenicals", | |
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| [ | |
| "Arsenicals", | |
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| [ | |
| "OP insecticides", | |
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| [ | |
| "OP insecticides", | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
| "Malathion", | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
| "Terbufos", | |
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| [ | |
| "Carbamate insecticides", | |
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| [ | |
| "Carbamate insecticides", | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
| "Carbaryl", | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
| "OC insecticides", | |
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| [ | |
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| [ | |
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| [ | |
| "DDT", | |
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| [ | |
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| [ | |
| "Lindane", | |
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| [ | |
| "Pyrethroid insecticides", | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
| "Permethrin", | |
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| [ | |
| "(Phenyl) urea herbicides", | |
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| [ | |
| "(Phenyl) urea herbicides", | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
| "Dicamba", | |
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| [ | |
| "Chloroacetanilides", | |
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| [ | |
| "Chloroacetanilides", | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
| "Dinitroaniline herbicides", | |
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| [ | |
| "Dinitroaniline herbicides", | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
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| [ | |
| "Triazinone herbicides", | |
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| [ | |
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| [ | |
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| [ | |
| "Metribuzin", | |
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| [ | |
| "Dithiocarbamate fungicides", | |
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| [ | |
| "Dithiocarbamate fungicides", | |
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| [ | |
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| [ | |
| "Mancozeb", | |
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| [ | |
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| [ | |
| "Thiram", | |
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| [ | |
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| [ | |
| "Phthalimide fungicides", | |
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| [ | |
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| [ | |
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| "source": [ | |
| "pd.options.plotting.backend = \"plotly\"\n", | |
| "fig = df_intermediate.plot.scatter(\"HRb\",\"se\", hover_data=['Insecticides', 'cancer_type', \"p_value\"],\n", | |
| " color= \"reject_null\",\n", | |
| " title='Funnel Plot')\n", | |
| "fig.update_yaxes(range=[.3, 0])\n", | |
| "fig.update_xaxes(range=[1-.65, 1.65])\n", | |
| "\n" | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": 217, | |
| "id": "3894898c-9846-4d02-94a4-81947a8a2801", | |
| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T18:46:34.338071Z", | |
| "iopub.status.busy": "2024-04-16T18:46:34.337645Z", | |
| "iopub.status.idle": "2024-04-16T18:46:34.582730Z", | |
| "shell.execute_reply": "2024-04-16T18:46:34.582489Z", | |
| "shell.execute_reply.started": "2024-04-16T18:46:34.338055Z" | |
| } | |
| }, | |
| "outputs": [], | |
| "source": [ | |
| "import seaborn as sns" | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": 255, | |
| "id": "8db38ecb-eeb6-4a3d-809f-baeadd63282c", | |
| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T19:01:44.685765Z", | |
| "iopub.status.busy": "2024-04-16T19:01:44.673164Z", | |
| "iopub.status.idle": "2024-04-16T19:01:44.922649Z", | |
| "shell.execute_reply": "2024-04-16T19:01:44.921070Z", | |
| "shell.execute_reply.started": "2024-04-16T19:01:44.685694Z" | |
| } | |
| }, | |
| "outputs": [ | |
| { | |
| "name": "stderr", | |
| "output_type": "stream", | |
| "text": [ | |
| "/Users/adrienpacifico/anaconda3/lib/python3.11/site-packages/seaborn/_oldcore.py:1119: FutureWarning: use_inf_as_na option is deprecated and will be removed in a future version. Convert inf values to NaN before operating instead.\n", | |
| " with pd.option_context('mode.use_inf_as_na', True):\n" | |
| ] | |
| }, | |
| { | |
| "data": { | |
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", | |
| "text/plain": [ | |
| "<Figure size 640x480 with 1 Axes>" | |
| ] | |
| }, | |
| "metadata": {}, | |
| "output_type": "display_data" | |
| } | |
| ], | |
| "source": [ | |
| "sns.set(style=\"whitegrid\")\n", | |
| "\n", | |
| "# Plotting the KDE Plot\n", | |
| "sns.kdeplot(df_intermediate[\"p_value\"].dropna(), fill=True, color=\"r\",clip=(0,1) )\n", | |
| "\n", | |
| "# Adding labels and title\n", | |
| "plt.title('KDE of P-values')\n", | |
| "plt.xlabel('P-value')\n", | |
| "plt.ylabel('Density')\n", | |
| "\n", | |
| "# Display the plot\n", | |
| "plt.show()" | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": 256, | |
| "id": "cdb1bb35-adbb-4357-9459-4cf018ccfbc3", | |
| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T19:01:45.688741Z", | |
| "iopub.status.busy": "2024-04-16T19:01:45.688436Z", | |
| "iopub.status.idle": "2024-04-16T19:01:45.831370Z", | |
| "shell.execute_reply": "2024-04-16T19:01:45.828219Z", | |
| "shell.execute_reply.started": "2024-04-16T19:01:45.688723Z" | |
| } | |
| }, | |
| "outputs": [ | |
| { | |
| "name": "stderr", | |
| "output_type": "stream", | |
| "text": [ | |
| "/Users/adrienpacifico/anaconda3/lib/python3.11/site-packages/seaborn/_oldcore.py:1119: FutureWarning: use_inf_as_na option is deprecated and will be removed in a future version. Convert inf values to NaN before operating instead.\n", | |
| " with pd.option_context('mode.use_inf_as_na', True):\n" | |
| ] | |
| }, | |
| { | |
| "data": { | |
| "image/png": 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", | |
| "text/plain": [ | |
| "<Figure size 640x480 with 1 Axes>" | |
| ] | |
| }, | |
| "metadata": {}, | |
| "output_type": "display_data" | |
| } | |
| ], | |
| "source": [ | |
| "sns.set(style=\"whitegrid\")\n", | |
| "\n", | |
| "# Plotting the KDE Plot\n", | |
| "sns.kdeplot(np.random.uniform(0,1,250), fill=True, color=\"r\",clip=(0,1) )\n", | |
| "\n", | |
| "# Adding labels and title\n", | |
| "plt.title('KDE of P-values')\n", | |
| "plt.xlabel('P-value')\n", | |
| "plt.ylabel('Density')\n", | |
| "\n", | |
| "# Display the plot\n", | |
| "plt.show()" | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": 389, | |
| "id": "8ce998c1-2f8c-4b50-bd6b-aebb076f7b87", | |
| "metadata": { | |
| "execution": { | |
| "iopub.execute_input": "2024-04-16T20:02:26.776978Z", | |
| "iopub.status.busy": "2024-04-16T20:02:26.774971Z", | |
| "iopub.status.idle": "2024-04-16T20:02:26.801365Z", | |
| "shell.execute_reply": "2024-04-16T20:02:26.800327Z", | |
| "shell.execute_reply.started": "2024-04-16T20:02:26.776901Z" | |
| } | |
| }, | |
| "outputs": [ | |
| { | |
| "data": { | |
| "text/html": [ | |
| "<div>\n", | |
| "<style scoped>\n", | |
| " .dataframe tbody tr th:only-of-type {\n", | |
| " vertical-align: middle;\n", | |
| " }\n", | |
| "\n", | |
| " .dataframe tbody tr th {\n", | |
| " vertical-align: top;\n", | |
| " }\n", | |
| "\n", | |
| " .dataframe thead th {\n", | |
| " text-align: right;\n", | |
| " }\n", | |
| "</style>\n", | |
| "<table border=\"1\" class=\"dataframe\">\n", | |
| " <thead>\n", | |
| " <tr style=\"text-align: right;\">\n", | |
| " <th></th>\n", | |
| " <th>index</th>\n", | |
| " <th>Na</th>\n", | |
| " <th>Pe</th>\n", | |
| " <th>ci_lower_bound</th>\n", | |
| " <th>ci_upper_bound</th>\n", | |
| " <th>reject_null</th>\n", | |
| " <th>p_value_95</th>\n", | |
| " <th>p_value</th>\n", | |
| " </tr>\n", | |
| " </thead>\n", | |
| " <tbody>\n", | |
| " <tr>\n", | |
| " <th>index</th>\n", | |
| " <td>1.000000</td>\n", | |
| " <td>0.073514</td>\n", | |
| " <td>-0.248200</td>\n", | |
| " <td>-0.081427</td>\n", | |
| " <td>-0.065455</td>\n", | |
| " <td>-0.029726</td>\n", | |
| " <td>0.061388</td>\n", | |
| " <td>0.061388</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>Na</th>\n", | |
| " <td>0.073514</td>\n", | |
| " <td>1.000000</td>\n", | |
| " <td>-0.109938</td>\n", | |
| " <td>0.430790</td>\n", | |
| " <td>-0.376485</td>\n", | |
| " <td>0.184430</td>\n", | |
| " <td>-0.219222</td>\n", | |
| " <td>-0.219222</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>Pe</th>\n", | |
| " <td>-0.248200</td>\n", | |
| " <td>-0.109938</td>\n", | |
| " <td>1.000000</td>\n", | |
| " <td>0.145353</td>\n", | |
| " <td>-0.275329</td>\n", | |
| " <td>-0.051414</td>\n", | |
| " <td>0.093337</td>\n", | |
| " <td>0.093337</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>ci_lower_bound</th>\n", | |
| " <td>-0.081427</td>\n", | |
| " <td>0.430790</td>\n", | |
| " <td>0.145353</td>\n", | |
| " <td>1.000000</td>\n", | |
| " <td>-0.180084</td>\n", | |
| " <td>0.224906</td>\n", | |
| " <td>-0.403241</td>\n", | |
| " <td>-0.403241</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>ci_upper_bound</th>\n", | |
| " <td>-0.065455</td>\n", | |
| " <td>-0.376485</td>\n", | |
| " <td>-0.275329</td>\n", | |
| " <td>-0.180084</td>\n", | |
| " <td>1.000000</td>\n", | |
| " <td>-0.014188</td>\n", | |
| " <td>-0.336794</td>\n", | |
| " <td>-0.336794</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>reject_null</th>\n", | |
| " <td>-0.029726</td>\n", | |
| " <td>0.184430</td>\n", | |
| " <td>-0.051414</td>\n", | |
| " <td>0.224906</td>\n", | |
| " <td>-0.014188</td>\n", | |
| " <td>1.000000</td>\n", | |
| " <td>-0.308270</td>\n", | |
| " <td>-0.308270</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>p_value_95</th>\n", | |
| " <td>0.061388</td>\n", | |
| " <td>-0.219222</td>\n", | |
| " <td>0.093337</td>\n", | |
| " <td>-0.403241</td>\n", | |
| " <td>-0.336794</td>\n", | |
| " <td>-0.308270</td>\n", | |
| " <td>1.000000</td>\n", | |
| " <td>1.000000</td>\n", | |
| " </tr>\n", | |
| " <tr>\n", | |
| " <th>p_value</th>\n", | |
| " <td>0.061388</td>\n", | |
| " <td>-0.219222</td>\n", | |
| " <td>0.093337</td>\n", | |
| " <td>-0.403241</td>\n", | |
| " <td>-0.336794</td>\n", | |
| " <td>-0.308270</td>\n", | |
| " <td>1.000000</td>\n", | |
| " <td>1.000000</td>\n", | |
| " </tr>\n", | |
| " </tbody>\n", | |
| "</table>\n", | |
| "</div>" | |
| ], | |
| "text/plain": [ | |
| " index Na Pe ci_lower_bound ci_upper_bound \\\n", | |
| "index 1.000000 0.073514 -0.248200 -0.081427 -0.065455 \n", | |
| "Na 0.073514 1.000000 -0.109938 0.430790 -0.376485 \n", | |
| "Pe -0.248200 -0.109938 1.000000 0.145353 -0.275329 \n", | |
| "ci_lower_bound -0.081427 0.430790 0.145353 1.000000 -0.180084 \n", | |
| "ci_upper_bound -0.065455 -0.376485 -0.275329 -0.180084 1.000000 \n", | |
| "reject_null -0.029726 0.184430 -0.051414 0.224906 -0.014188 \n", | |
| "p_value_95 0.061388 -0.219222 0.093337 -0.403241 -0.336794 \n", | |
| "p_value 0.061388 -0.219222 0.093337 -0.403241 -0.336794 \n", | |
| "\n", | |
| " reject_null p_value_95 p_value \n", | |
| "index -0.029726 0.061388 0.061388 \n", | |
| "Na 0.184430 -0.219222 -0.219222 \n", | |
| "Pe -0.051414 0.093337 0.093337 \n", | |
| "ci_lower_bound 0.224906 -0.403241 -0.403241 \n", | |
| "ci_upper_bound -0.014188 -0.336794 -0.336794 \n", | |
| "reject_null 1.000000 -0.308270 -0.308270 \n", | |
| "p_value_95 -0.308270 1.000000 1.000000 \n", | |
| "p_value -0.308270 1.000000 1.000000 " | |
| ] | |
| }, | |
| "execution_count": 389, | |
| "metadata": {}, | |
| "output_type": "execute_result" | |
| } | |
| ], | |
| "source": [ | |
| "df_intermediate.corr(numeric_only=True)" | |
| ] | |
| }, | |
| { | |
| "cell_type": "code", | |
| "execution_count": null, | |
| "id": "c9068e8d-d680-4537-8823-c0b4e3cd6645", | |
| "metadata": {}, | |
| "outputs": [], | |
| "source": [] | |
| } | |
| ], | |
| "metadata": { | |
| "kernelspec": { | |
| "display_name": "Python 3 (ipykernel)", | |
| "language": "python", | |
| "name": "python3" | |
| }, | |
| "language_info": { | |
| "codemirror_mode": { | |
| "name": "ipython", | |
| "version": 3 | |
| }, | |
| "file_extension": ".py", | |
| "mimetype": "text/x-python", | |
| "name": "python", | |
| "nbconvert_exporter": "python", | |
| "pygments_lexer": "ipython3", | |
| "version": "3.11.5" | |
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| }, | |
| "nbformat": 4, | |
| "nbformat_minor": 5 | |
| } |
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