Partially. You can 100% go and download either arch1t3cht's fork or the official 3.4.2 and both will open in macOS out of the box, but you are limited to ffms2
as your video provider and both apps are more designed for the Intel (x86-64) versions of macOS rather than the new Apple Silicon (ARM64) devices, meaning that VapourSynth will not work on these versions as-is. If you are using an x86-64 Mac I'd 100% recommend using these official sources, and you can find good sources for VapourSynth packages here. (These packages will not work on Apple Silicon Macs!)
This tutorial is designed for those that would rather use a more accurate video provider with built-in keyframe & VapourSynth support on Apple Silicon compared to `F