My current settings for NetHack.

.nethackrc

#graphics
OPTIONS=windowtype:tty
OPTIONS=term_cols:210
OPTIONS=term_rows:50
OPTIONS=windowborders:2

#gameplay
OPTIONS=showexp,showscore,time,color
OPTIONS=!autopickup,!tutorial,!tips,!legacy,!implicit_uncursed
OPTIONS=autodig,fruit:abble,boulder:0

#highlighting
OPTIONS=statushilites

##health bar
OPTIONS=hilite_status: hitpoints-max/green&normal
OPTIONS=hilite_status: hitpoints/100%/green&normal
OPTIONS=hilite_status: hitpoints/<100%/lightgreen&normal
OPTIONS=hilite_status: hitpoints/<76%/yellow&normal
OPTIONS=hilite_status: hitpoints/<51%/orange&normal
OPTIONS=hilite_status: hitpoints/<26%/red&normal
OPTIONS=hilite_status: hitpoints/<11%/black&normal

##power
OPTIONS=hilite_status:power/100%/grey&normal
OPTIONS=hilite_status:power/<100%/green&normal
OPTIONS=hilite_status:power/<66%/yellow&normal
OPTIONS=hilite_status:power/<50%/orange&normal
OPTIONS=hilite_status:power/<33%/red&bold

##carry capacity
OPTIONS=hilite_status:cap/burdened/yellow/stressed/orange/strained/red&bold/overtaxed/red&inverse/overloaded/red&inverse&blink

##hunger and starvation
OPTIONS=hilite_status:hunger/satiated/yellow/hungry/orange/weak/red&bold/fainting/red&inverse/fainted/red&inverse&blink

##mental status
OPTIONS=hilite_status:condition/hallu/yellow
OPTIONS=hilite_status:condition/conf/orange
OPTIONS=hilite_status:condition/stun/red&bold

##status conditions
OPTIONS=hilite_status:condition/termill/red&inverse
OPTIONS=hilite_status:condition/foodpois/red&inverse
OPTIONS=hilite_status:condition/slime/red&inverse

##attribute changes
OPTIONS=hilite_status:characteristics/up/green/down/red

##BUC status
OPTIONS=menucolor
MENUCOLOR=" blessed "=green&bold
MENUCOLOR=" holy "=green&bold
MENUCOLOR=" cursed "=red&bold
MENUCOLOR=" unholy "=red&bold
MENUCOLOR="gold piece"=yellow

#control
OPTIONS=paranoid_confirmation:attack pray Remove
OPTIONS=number_pad:1