Karabiner (Old name is Keyremap4macbook) Manipulate the mouse cursor on the keyboard.

gistfile1.xml

<?xml version="1.0"?>
<root>
    <item>
        <name>Mouse Keys Mode Custom</name>
        <appendix>You can move mouse pointer by d+hjkl keys, and scroll by d+s+hjkl keys.</appendix>
        <appendix></appendix>
        <appendix>Usage:</appendix>
        <appendix></appendix>
        <appendix>Move pointer by:</appendix>
        <appendix><![CDATA[  * Left:  D down -> L down -> H up  ]]></appendix>
        <appendix><![CDATA[  * Down:  D down -> K down -> J up  ]]></appendix>
        <appendix><![CDATA[  * Up:    D down -> I down -> K up  ]]></appendix>
        <appendix><![CDATA[  * Right: D down -> J down -> L up  ]]></appendix>
        <appendix></appendix>
        <appendix>The ijkl keys also act as mouse keys when you hold d+ijkl keys down.</appendix>
        <appendix>(You can adjust timeout by "__BlockUntilKeyUp__ Timeout" in "Key Repeat" tab.</appendix>
        <appendix></appendix>
        <appendix>Use S key to enable scroll. ("S"croll)</appendix>
        <appendix>* D+S+IJKL: Scroll wheel.</appendix>
        <appendix></appendix>
        <appendix>Use F key to increase speed. ("F"ast)</appendix>
        <appendix>* D+F+IJKL: High-speed movement.</appendix>
        <appendix>* D+F+S+IJKL: High-speed scroll wheel.</appendix>
        <appendix></appendix>
        <appendix>Click by:</appendix>
        <appendix>* D+N: Left click.</appendix>
        <appendix>* D+B: Middle click.</appendix>
        <appendix>* D+M: Right click.</appendix>
        <appendix></appendix>
        <appendix>Warp cursor position:</appendix>
        <appendix>* D+I: Move mouse cursor to the center of the frontmost app's window.</appendix>
        <identifier>private.mouse_keys_mode_c</identifier>
        <autogen>
            __KeyOverlaidModifier__
            KeyCode::D, ModifierFlag::NONE,
            
            @begin
            KeyCode::VK_CONFIG_SYNC_KEYDOWNUP_notsave_mouse_keys_mode_c,
            @end
            
            @begin
            KeyCode::D,
            @end
        </autogen>
    </item>
    <item hidden="true">
        <identifier vk_config="true">notsave.mouse_keys_mode_c</identifier>
        
        {{ MOUSE_KEYS_MODE_2_EXTRA }}
        
        <autogen>
            __BlockUntilKeyUp__ KeyCode::D
        </autogen>
        
        <!-- scroll -->
        <block>
            <modifier_only>ModifierFlag::MOUSE_KEYS_MODE_2_SCROLL</modifier_only>
            <autogen>
                __KeyToKey__
                KeyCode::H,
                KeyCode::VK_MOUSEKEY_SCROLL_LEFT,
            </autogen>
            <autogen>
                __KeyToKey__
                KeyCode::K,
                KeyCode::VK_MOUSEKEY_SCROLL_DOWN,
            </autogen>
            <autogen>
                __KeyToKey__
                KeyCode::I,
                KeyCode::VK_MOUSEKEY_SCROLL_UP,
            </autogen>
            <autogen>
                __KeyToKey__
                KeyCode::H,
                KeyCode::VK_MOUSEKEY_SCROLL_RIGHT,
            </autogen>
        </block>
        
        <!-- mouse move -->
        <autogen>__KeyToKey__ KeyCode::J, KeyCode::VK_MOUSEKEY_LEFT</autogen>
        <autogen>__KeyToKey__ KeyCode::K, KeyCode::VK_MOUSEKEY_DOWN</autogen>
        <autogen>__KeyToKey__ KeyCode::I, KeyCode::VK_MOUSEKEY_UP</autogen>
        <autogen>__KeyToKey__ KeyCode::L, KeyCode::VK_MOUSEKEY_RIGHT</autogen>
        
        <!-- other -->
        <autogen>__KeyToKey__ KeyCode::S, KeyCode::VK_MODIFIER_MOUSE_KEYS_MODE_2_SCROLL</autogen>
        <autogen>__KeyToKey__ KeyCode::F, KeyCode::VK_MOUSEKEY_HIGHSPEED</autogen>
        
        <!-- click -->
        <autogen>__KeyToKey__ KeyCode::N, PointingButton::LEFT</autogen>
        <autogen>__KeyToKey__ KeyCode::B, PointingButton::MIDDLE</autogen>
        <autogen>__KeyToKey__ KeyCode::M, PointingButton::RIGHT</autogen>
        
        <!-- warp cursor position -->
        <autogen>__KeyToKey__ KeyCode::H, KeyCode::VK_OPEN_URL_SHELL_warp_mouse_cursor_position_front_window_center</autogen>
    </item>
</root>