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causative.nwt for testing
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<glyph id="nwtN_a9ab5c37-bfcd-4a65-983f-807cd8a5dda1" class="SIF macromolecule"> | |
<label text="TTK"/> | |
<bbox x="-127.84467453415283" y="144.1107683075926" w="38.330078125" h="30"/> | |
<glyph id="nwtUOI_d7fca050-d750-4d21-8364-f5c43c989c3f" class="unit of information"> | |
<label text="p"/> | |
<bbox x="-122.84467453415283" y="136.6107683075926" w="15" h="15"/> | |
</glyph> | |
</glyph> | |
<glyph id="nwtN_109e92da-f57d-405a-ae3a-4cfc6d95cd22" class="SIF macromolecule"> | |
<label text="KIF11"/> | |
<bbox x="-187.42475265915283" y="35.36076830759261" w="48.91357421875" h="30"/> | |
<glyph id="nwtUOI_10202e7c-4e0e-47a5-8fcb-5284bf711189" class="unit of information"> | |
<label text="p"/> | |
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<glyph id="nwtUOI_391844a4-d074-4e89-87c5-8f6647dbe77f" class="unit of information"> | |
<label text="p"/> | |
<bbox x="-182.42475265915283" y="57.86076830759261" w="15" h="15"/> | |
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</glyph> | |
<glyph id="nwtN_9206b3f9-2077-45c2-9fd8-f4c187945ea1" class="SIF macromolecule"> | |
<label text="GOLGA2"/> | |
<bbox x="-132.83246750290283" y="-0.8892316924073924" w="71.69189453125" h="30"/> | |
<glyph id="nwtUOI_6d12df39-7bc2-4bea-b93c-cbc7faf98b15" class="unit of information"> | |
<label text="p"/> | |
<bbox x="-127.83246750290283" y="-8.389231692407392" w="15" h="15"/> | |
</glyph> | |
</glyph> | |
<glyph id="nwtN_937a83fb-7a5b-4dd8-ad54-ea771737fa3b" class="SIF macromolecule"> | |
<label text="PAICS"/> | |
<bbox x="-129.49994797165283" y="107.86076830759261" w="53.90869140625" h="30"/> | |
<glyph id="nwtUOI_e784ee56-c1a0-4aa4-b7df-f99727569492" class="unit of information"> | |
<label text="p"/> | |
<bbox x="-124.49994797165283" y="100.36076830759261" w="15" h="15"/> | |
</glyph> | |
</glyph> | |
<glyph id="nwtN_34275177-b663-4172-9a54-c701bb150dd1" class="SIF macromolecule"> | |
<label text="CDC25C"/> | |
<bbox x="-131.99018234665283" y="-37.13923169240739" w="70.0146484375" h="30"/> | |
<glyph id="nwtUOI_eb1a4218-648e-4d8d-a35a-b1343ffafc6c" class="unit of information"> | |
<label text="p"/> | |
<bbox x="-126.99018234665283" y="-44.63923169240739" w="15" h="15"/> | |
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<glyph id="nwtUOI_3d5d158a-a61c-4203-a7ea-a1cb62914820" class="unit of information"> | |
<label text="p"/> | |
<bbox x="-126.99018234665283" y="-14.639231692407392" w="15" h="15"/> | |
</glyph> | |
</glyph> | |
<glyph id="nwtN_64eae22f-bde8-4382-8527-0a6aea04c62c" class="SIF macromolecule"> | |
<label text="FLNA"/> | |
<bbox x="-187.42475265915283" y="-0.8892316924073924" w="48.34228515625" h="30"/> | |
<glyph id="nwtUOI_6967a62e-1894-43fb-8154-1d2b578286a2" class="unit of information"> | |
<label text="p"/> | |
<bbox x="-182.42475265915283" y="-8.389231692407392" w="15" h="15"/> | |
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</glyph> | |
<glyph id="nwtN_2e5699e0-0a8e-4dcd-b04a-759ed5cb539e" class="SIF macromolecule"> | |
<label text="NCL"/> | |
<bbox x="-187.42475265915283" y="71.61076830759261" w="40.00732421875" h="30"/> | |
<glyph id="nwtUOI_bf155f0b-ff7f-490b-b86d-83a8c8d14088" class="unit of information"> | |
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<label text="p"/> | |
<bbox x="-191.42328781540283" y="94.11076830759261" w="15" h="15"/> | |
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<glyph id="nwtUOI_7c3c9df4-48b0-48c8-bf06-2c45102598d1" class="unit of information"> | |
<label text="p"/> | |
<bbox x="-180.42182297165283" y="64.11076830759261" w="15" h="15"/> | |
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<glyph id="nwtUOI_3af765a9-099d-4fa4-8a37-625104071dee" class="unit of information"> | |
<label text="p"/> | |
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<glyph id="nwtUOI_5454af28-add8-42d0-93dd-2941df85fc9c" class="unit of information"> | |
<label text="p"/> | |
<bbox x="-169.42035812790283" y="64.11076830759261" w="15" h="15"/> | |
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<glyph id="nwtUOI_5e530dc8-9a23-49bd-877a-5c9a67165fc9" class="unit of information"> | |
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<glyph id="nwtUOI_edac680f-d975-45f0-99bd-2e1874200540" class="unit of information"> | |
<label text="p"/> | |
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<glyph id="nwtUOI_783be937-c080-467f-8ad1-9a9256fcb956" class="unit of information"> | |
<label text="p"/> | |
<bbox x="-158.41889328415283" y="94.11076830759261" w="15" h="15"/> | |
</glyph> | |
</glyph> | |
<glyph id="nwtN_9b0291df-8086-4daa-9913-fc27e39806fd" class="SIF macromolecule"> | |
<label text="TMPO"/> | |
<bbox x="-187.42475265915283" y="144.1107683075926" w="53.330078125" h="30"/> | |
<glyph id="nwtUOI_cb2927e6-3bfa-4757-832f-64121fe801f7" class="unit of information"> | |
<label text="p"/> | |
<bbox x="-182.42475265915283" y="136.6107683075926" w="15" h="15"/> | |
</glyph> | |
</glyph> | |
<glyph id="nwtN_95ffda43-b332-4b28-83b7-a4d1851f1c5a" class="SIF macromolecule"> | |
<label text="BUB1"/> | |
<bbox x="-187.42475265915283" y="-37.13923169240739" w="49.1845703125" h="30"/> | |
<glyph id="nwtUOI_fbc89456-b7d7-4777-ab68-669b7f3e2b6a" class="unit of information"> | |
<label text="p"/> | |
<bbox x="-182.42475265915283" y="-44.63923169240739" w="15" h="15"/> | |
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<glyph id="nwtUOI_c3d2ca82-8c06-478a-9b81-cc7057a76343" class="unit of information"> | |
<label text="p"/> | |
<bbox x="-182.42475265915283" y="-14.639231692407392" w="15" h="15"/> | |
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</glyph> | |
</glyph> | |
<glyph id="nwtN_61b7e77d-8b4b-4f9c-997e-6b5c5f53b315" class="topology group"> | |
<extension> | |
<extraInfo> | |
<w>77.4541015625</w> | |
<h>85.75</h> | |
<minW>0</minW> | |
<minH>0</minH> | |
<WLBias>0</WLBias> | |
<WRBias>0</WRBias> | |
<HTBias>0</HTBias> | |
<HBBias>0</HBBias> | |
</extraInfo> | |
</extension> | |
<bbox x="-88.56643227583781" y="-197.8607683075926" w="105.4541015625" h="113.75"/> | |
<glyph id="nwtN_4f5849ee-0616-439b-99fd-847c8b982ef3" class="SIF macromolecule"> | |
<label text="TP53BP1"/> | |
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<glyph id="nwtUOI_d7f8f081-cb4d-4423-92ba-f265647c3658" class="unit of information"> | |
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<glyph id="nwtUOI_e1eae2b2-359f-4ca9-a7b4-3787290cc6b2" class="unit of information"> | |
<label text="p"/> | |
<bbox x="-67.94143227583781" y="-115.3607683075926" w="15" h="15"/> | |
</glyph> | |
</glyph> | |
<glyph id="nwtN_a4edd411-6c99-4a09-84ef-991cba86661d" class="SIF macromolecule"> | |
<label text="PTPN1"/> | |
<bbox x="-72.94143227583781" y="-174.1107683075926" w="58.34716796875" h="30"/> | |
<glyph id="nwtUOI_0b1fca5b-42a5-40d8-9607-4d62ed3a70f0" class="unit of information"> | |
<label text="p"/> | |
<bbox x="-67.94143227583781" y="-181.6107683075926" w="15" h="15"/> | |
</glyph> | |
</glyph> | |
</glyph> | |
<glyph id="nwtN_425ead71-6a8e-4480-8133-7aa659be5eae" class="SIF macromolecule"> | |
<label text="ERCC6L"/> | |
<bbox x="132.23774094040283" y="2.8263208212700945" w="69.18701171875" h="30"/> | |
<glyph id="nwtUOI_5d31a6c2-4ad4-44dd-8f0a-a3f11710cabf" class="unit of information"> | |
<label text="p"/> | |
<bbox x="137.23774094040283" y="-4.6736791787299055" w="15" h="15"/> | |
<tooltip>Q2NKX8_S807, 0.944781725858588</tooltip> | |
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<glyph id="nwtUOI_a94bd736-572e-4ed4-9a8f-730e7550a17b" class="unit of information"> | |
<label text="p"/> | |
<bbox x="137.23774094040283" y="25.326320821270095" w="15" h="15"/> | |
<tooltip>Q2NKX8_T1063, 0.760778026209911</tooltip> | |
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<glyph id="nwtUOI_047bcf68-1b25-4b23-8127-f3ee96145bcc" class="unit of information"> | |
<label text="p"/> | |
<bbox x="157.23774094040283" y="-4.6736791787299055" w="15" h="15"/> | |
<tooltip>Q2NKX8_S995, 1.38093471207609</tooltip> | |
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<glyph id="nwtUOI_a76dc976-a381-47ee-9ab9-a8b3b81dcd76" class="unit of information"> | |
<label text="p"/> | |
<bbox x="157.23774094040283" y="25.326320821270095" w="15" h="15"/> | |
<tooltip>Q2NKX8_S1000@Q2NKX8, 0.760083041223619</tooltip> | |
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<arc id="nwtE_6e448c7e-81d1-4d06-88a3-2c41b6bb4029" class="phosphorylates" source="nwtN_f045c240-776a-4ba1-a18e-d74138c940b8" target="nwtN_425ead71-6a8e-4480-8133-7aa659be5eae"> | |
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<start x="104.29434144695293" y="-37.8342007577805"/> | |
<end x="138.65547638627203" y="-7.251320425275416"/> | |
<pcIDs>PMID:17218258</pcIDs> | |
<siteLocations>T1063</siteLocations> | |
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<arc id="nwtE_f8bf938c-50a1-4629-80f2-4f951cf77ec4" class="phosphorylates" source="nwtN_df4c99cf-f82b-4dd0-9b54-34803e40a365" target="nwtN_425ead71-6a8e-4480-8133-7aa659be5eae"> | |
<extension> | |
<curveStyle>bezier</curveStyle> | |
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<start x="67.13461697527168" y="25.76922461567648"/> | |
<end x="128.4976118273339" y="20.880389702153877"/> | |
<pcIDs>http://pathwaycommons.org/pc12/Catalysis_1dff1864813f23e95b7d08d2c63a43f4;http://pathwaycommons.org/pc12/BiochemicalReaction_ef0e1f07401b7648c465549f61b41beb;PMID:17218258</pcIDs> | |
<siteLocations>T1063</siteLocations> | |
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<arc id="nwtE_6b75470d-7452-48a4-a4e5-7fb0908c3ad3" class="phosphorylates" source="nwtN_df4c99cf-f82b-4dd0-9b54-34803e40a365" target="nwtN_6988f8cf-f410-4947-bf98-53cae95dfb24"> | |
<extension> | |
<curveStyle>bezier</curveStyle> | |
<sifMetaEdge>true</sifMetaEdge> | |
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<start x="15.872409944021683" y="33.393767871912424"/> | |
<end x="-41.83715710336294" y="45.96300174834989"/> | |
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<arc id="nwtE_b69be4e6-43ca-42ee-93ae-dc94e6a89b30" class="phosphorylates" source="nwtN_f045c240-776a-4ba1-a18e-d74138c940b8" target="nwtN_61b7e77d-8b4b-4f9c-997e-6b5c5f53b315"> | |
<extension> | |
<curveStyle>bezier</curveStyle> | |
<sifMetaEdge>true</sifMetaEdge> | |
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<start x="66.75548299112786" y="-67.70393583056232"/> | |
<end x="20.055588888054658" y="-101.06090582619935"/> | |
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<arc id="nwtE_7a9ca91d-d378-4c16-b634-da7f5e6ffbcd" class="phosphorylates" source="nwtN_df4c99cf-f82b-4dd0-9b54-34803e40a365" target="nwtN_dcc4fe0a-453f-4398-9b7b-156da17ed95f"> | |
<extension> | |
<curveStyle>bezier</curveStyle> | |
</extension> | |
<start/> | |
<end/> | |
</arc> | |
<arc id="nwtE_91dc371d-cfb5-40cf-9147-15e06ec5ac23" class="phosphorylates" source="nwtN_df4c99cf-f82b-4dd0-9b54-34803e40a365" target="nwtN_e807d8a3-8945-4533-8bf6-9bb10557513d"> | |
<extension> | |
<curveStyle>bezier</curveStyle> | |
</extension> | |
<start/> | |
<end/> | |
</arc> | |
<arc id="nwtE_ec42c450-4949-4f6e-b17c-a778162e6ded" class="phosphorylates" source="nwtN_df4c99cf-f82b-4dd0-9b54-34803e40a365" target="nwtN_8897a77e-54d6-459a-b201-84aa7c7235a6"> | |
<extension> | |
<curveStyle>bezier</curveStyle> | |
</extension> | |
<start/> | |
<end/> | |
</arc> | |
<arc id="nwtE_2c64ccf0-a4d1-4bed-957c-c2acece7439c" class="phosphorylates" source="nwtN_df4c99cf-f82b-4dd0-9b54-34803e40a365" target="nwtN_a9ab5c37-bfcd-4a65-983f-807cd8a5dda1"> | |
<extension> | |
<curveStyle>bezier</curveStyle> | |
</extension> | |
<start/> | |
<end/> | |
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<arc id="nwtE_d5de2c0b-f253-4f76-ae65-c6005509c350" class="phosphorylates" source="nwtN_df4c99cf-f82b-4dd0-9b54-34803e40a365" target="nwtN_109e92da-f57d-405a-ae3a-4cfc6d95cd22"> | |
<extension> | |
<curveStyle>bezier</curveStyle> | |
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<start/> | |
<end/> | |
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<arc id="nwtE_5454177b-0ace-41ff-b543-2cc367ede285" class="phosphorylates" source="nwtN_df4c99cf-f82b-4dd0-9b54-34803e40a365" target="nwtN_9206b3f9-2077-45c2-9fd8-f4c187945ea1"> | |
<extension> | |
<curveStyle>bezier</curveStyle> | |
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<start/> | |
<end/> | |
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<arc id="nwtE_6ae8b2a4-dc49-4aa3-b248-8013349eade0" class="phosphorylates" source="nwtN_df4c99cf-f82b-4dd0-9b54-34803e40a365" target="nwtN_937a83fb-7a5b-4dd8-ad54-ea771737fa3b"> | |
<extension> | |
<curveStyle>bezier</curveStyle> | |
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<start/> | |
<end/> | |
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<arc id="nwtE_3b62ce3c-a94b-4e1f-b3e3-e778963412ee" class="phosphorylates" source="nwtN_df4c99cf-f82b-4dd0-9b54-34803e40a365" target="nwtN_34275177-b663-4172-9a54-c701bb150dd1"> | |
<extension> | |
<curveStyle>bezier</curveStyle> | |
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<start/> | |
<end/> | |
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<arc id="nwtE_bce6fdfa-ef02-4a01-b2ad-953cde9bbbca" class="phosphorylates" source="nwtN_df4c99cf-f82b-4dd0-9b54-34803e40a365" target="nwtN_64eae22f-bde8-4382-8527-0a6aea04c62c"> | |
<extension> | |
<curveStyle>bezier</curveStyle> | |
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<end/> | |
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<arc id="nwtE_eba53e8d-6426-442c-8533-71044c7c3d00" class="phosphorylates" source="nwtN_df4c99cf-f82b-4dd0-9b54-34803e40a365" target="nwtN_2e5699e0-0a8e-4dcd-b04a-759ed5cb539e"> | |
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<curveStyle>bezier</curveStyle> | |
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<start/> | |
<end/> | |
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<arc id="nwtE_7a517cb9-3f04-4cc9-a1d4-e59116e95546" class="phosphorylates" source="nwtN_df4c99cf-f82b-4dd0-9b54-34803e40a365" target="nwtN_9b0291df-8086-4daa-9913-fc27e39806fd"> | |
<extension> | |
<curveStyle>bezier</curveStyle> | |
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<start/> | |
<end/> | |
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<arc id="nwtE_a9674619-5bcf-4c0d-be87-dfb59ce3f6d0" class="phosphorylates" source="nwtN_df4c99cf-f82b-4dd0-9b54-34803e40a365" target="nwtN_95ffda43-b332-4b28-83b7-a4d1851f1c5a"> | |
<extension> | |
<curveStyle>bezier</curveStyle> | |
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<start/> | |
<end/> | |
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<arc id="nwtE_55a6b0cc-ab1a-4906-af4a-9edc2abe77f8" class="phosphorylates" source="nwtN_f045c240-776a-4ba1-a18e-d74138c940b8" target="nwtN_4f5849ee-0616-439b-99fd-847c8b982ef3"> | |
<extension> | |
<curveStyle>bezier</curveStyle> | |
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<start/> | |
<end/> | |
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<arc id="nwtE_8a94c859-bbec-45d6-bbbb-ada1ecbdcf65" class="phosphorylates" source="nwtN_f045c240-776a-4ba1-a18e-d74138c940b8" target="nwtN_a4edd411-6c99-4a09-84ef-991cba86661d"> | |
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CDK1 phosphorylates CDC25C PMID:18669648 PMID:18691976 PMID:20068231 PMID:18212344 PMID:10037602 PMID:12766774 PMID:10864927 PMID:16964243 PMID:8119945 T67;S214;S168;S122;T48;T130 | |
PLK1 phosphorylates TP53BP1 PMID:25607646 S1618 | |
CDK1 phosphorylates GOLGA2 PMID:18669648 PMID:10769027 PMID:18691976 PMID:20068231 http://identifiers.org/reactome/R-HSA-2172183 PMID:19007248 PMID:19691289 PMID:9753325 PMID:16964243 http://pathwaycommons.org/pc12/Catalysis_02b70931d30eb9787f1b41a249d51cf9 S37 | |
CDK1 phosphorylates NOLC1 PMID:18234856 T610;T607 | |
CDK1 phosphorylates CDCA5 http://identifiers.org/reactome/R-HSA-2468293 http://identifiers.org/reactome/R-HSA-2468287 PMID:21987589 PMID:21878504 PMID:23901111 http://pathwaycommons.org/pc12/Catalysis_586bb2cda022b46eba851263f52c0def http://pathwaycommons.org/pc12/Catalysis_25c3b62cbd8ca3039684a857bdca851b S139;S126;T159;T115;S209;S83;S75;S181;S33;S21;S79;T48;S164;T111;T151 | |
CDK1 phosphorylates KIF11 PMID:20068230 PMID:20068231 PMID:16565220 PMID:19664994 PMID:19007248 PMID:9235942 PMID:19691289 PMID:19413330 PMID:8548803 T926 | |
CDK1 phosphorylates NCAPG http://identifiers.org/reactome/R-HSA-2514854 PMID:18977199 http://pathwaycommons.org/pc12/Catalysis_e6ddb6a1563fc6ce2b800fe3a8e0d560 T308;T931;T332 | |
CDK1 phosphorylates NPM1 PMID:18669648 PMID:20068231 PMID:14670079 PMID:18234856 PMID:15190079 PMID:12058066 PMID:11278991 PMID:17287340 PMID:19933706 PMID:16912078 PMID:17924679 T219;T208;T237;T205;T234;T199;S70 | |
CDK1 phosphorylates PAICS PMID:18234856 S27 | |
CDK1 phosphorylates TTK S281 | |
PLK1 phosphorylates CIP2A S904 | |
PLK1 phosphorylates PINX1 PMID:20573420 S117;T317;S226;S110;T141;S161 | |
CDK1 phosphorylates ERCC6L http://pathwaycommons.org/pc12/Catalysis_1dff1864813f23e95b7d08d2c63a43f4 http://pathwaycommons.org/pc12/BiochemicalReaction_ef0e1f07401b7648c465549f61b41beb PMID:17218258 T1063 | |
PLK1 phosphorylates ERCC6L PMID:17218258 T1063 | |
PLK1 phosphorylates PTPN1 PMID:23348582 S286;S393 | |
CDK1 phosphorylates NCL PMID:21998300 PMID:18234856 T641;T121;T707 | |
CDK1 phosphorylates BUB1 http://pathwaycommons.org/pc12/Catalysis_47462092c1fa80112cbc96df72b9a20e http://pathwaycommons.org/pc12/BiochemicalReaction_ef5f9371a963616edcd45a682f7bd027 PMID:16760428 S593;T609 | |
CDK1 phosphorylates FLNA PMID:17408621 PMID:25445790 S1436;S1459;S1084;S1630;S1533 | |
CDK1 phosphorylates TMPO PMID:18234856 S424 | |
CDK1 phosphorylates NCAPD2 http://identifiers.org/reactome/R-HSA-2514854 http://pathwaycommons.org/pc12/Catalysis_e6ddb6a1563fc6ce2b800fe3a8e0d560 T1389;T1384;T1339 | |
CDK1 phosphorylates VCPIP1 http://identifiers.org/reactome/R-HSA-8940100 http://pathwaycommons.org/pc12/Catalysis_9fa49578c4f5733ca8db3a6308385b5d PMID:23500464 S768;T761;S131 | |
CDK1 phosphorylates TPX2 PMID:18234856 PMID:25688093 T72;S738 |
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