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Analytical derivation of the prior XSwap probability of a hetnet edge
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metaedge | abbreviation | n_edges | n_connected_source_nodes | n_connected_target_nodes | n_source_wedges | n_target_wedges | n_wedges | n_valid_xswaps | |
---|---|---|---|---|---|---|---|---|---|
Anatomy–downregulates–Gene | AdG | 102240 | 36 | 15097 | 173440264 | 493897 | 173934161 | 5052523519 | |
Anatomy–expresses–Gene | AeG | 526407 | 241 | 18094 | 2290279787 | 10749138 | 2301028925 | 136250872696 | |
Anatomy–upregulates–Gene | AuG | 97848 | 36 | 15929 | 149352969 | 359661 | 149712630 | 4637353998 | |
Compound–binds–Gene | CbG | 11571 | 1389 | 1689 | 104024 | 476540 | 580564 | 66357671 | |
Compound–causes–Side Effect | CcSE | 138944 | 1071 | 5701 | 16998055 | 16764774 | 33762829 | 9618885267 | |
Compound–downregulates–Gene | CdG | 21102 | 734 | 2880 | 1683615 | 291789 | 1975404 | 220661247 | |
Compound–palliates–Disease | CpD | 390 | 221 | 50 | 326 | 2857 | 3183 | 72672 | |
Compound–resembles–Compound | CrC | 12972 | 1281 | 1281 | 120047 | 120047 | 240094 | 83889812 | |
Compound–treats–Disease | CtD | 755 | 387 | 77 | 1420 | 8070 | 9490 | 275145 | |
Compound–upregulates–Gene | CuG | 18756 | 703 | 3247 | 1489248 | 183634 | 1672882 | 174211508 | |
Disease–associates–Gene | DaG | 12623 | 134 | 5392 | 1581400 | 35550 | 1616950 | 78046803 | |
Disease–downregulates–Gene | DdG | 7623 | 44 | 5745 | 884813 | 2498 | 887311 | 28163942 | |
Disease–localizes–Anatomy | DlA | 3602 | 133 | 398 | 72644 | 19982 | 92626 | 6392775 | |
Disease–presents–Symptom | DpS | 3357 | 133 | 415 | 64389 | 23430 | 87819 | 5545227 | |
Disease–resembles–Disease | DrD | 1086 | 129 | 129 | 6531 | 6531 | 13062 | 576093 | |
Disease–upregulates–Gene | DuG | 7731 | 44 | 5630 | 909467 | 3031 | 912498 | 28967817 | |
Gene–covaries–Gene | GcG | 123380 | 12453 | 12453 | 3702610 | 3702610 | 7405220 | 7603845290 | |
Gene–interacts–Gene | GiG | 294328 | 15165 | 15165 | 55412782 | 55412782 | 110825564 | 43203513064 | |
Gene–participates–Biological Process | GpBP | 559504 | 14772 | 11381 | 30123408 | 90103196 | 120226604 | 156401856652 | |
Gene–participates–Cellular Component | GpCC | 73566 | 10580 | 1391 | 456449 | 12531792 | 12988241 | 2692953154 | |
Gene–participates–Molecular Function | GpMF | 97222 | 13063 | 2884 | 591373 | 15444939 | 16036312 | 4709973719 | |
Gene–participates–Pathway | GpPW | 84372 | 8979 | 1822 | 1337526 | 11008146 | 12345672 | 3546929334 | |
Gene→regulates→Gene | Gr>G | 265672 | 4634 | 7048 | 15056962 | 37821797 | 52878759 | 35237794197 | |
Pharmacologic Class–includes–Compound | PCiC | 1029 | 345 | 724 | 3156 | 603 | 3759 | 525147 |
Updated figure from this notebook that includes two metaedges:
Includes Disease-associates-Gene data from greenelab/snorkeling#67.
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Here is the outputted
estimated-xswap-priors.png
: