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readme-flare-imports.json
[
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]
Raw
readme.md

An implementation of Danny Holten's hierarchical edge bundling algorithm in D3, showing dependencies between classes in a software class hierarchy. Dependencies are bundled according to the parent packages. This example uses two layouts: a radial d3.layout.cluster to position the tree nodes, and d3.layout.bundle to group the dependencies into spline bundles. Thanks to Jason Davies for contributing the layout implementation!

Raw
human_up_10.json
[
{
"Cluster" : 1,
"name" : "GO:0009611~response to wounding",
"Term 1" : "GO:0009611",
"Term 2" : "response to wounding",
"size" : 61,
"%" : 10.42735043,
"PValue" : 6.16E-16,
"imports" : [ 3627, 1001, 2919, 3084, 8767, 3620, 1051, 6352, 6351, 7168, 3678, 7852, 2151, 5329, 5265, 5328, 3576, 6648, 5588, 7037, 308, 7941, 3694, 131566, 929, 4973, 5359, 6364, 6696, 9111, 1490, 6288, 2768, 1230, 313, 12, 10563, 7040, 10630, 6373, 3556, 3553, 3559, 629, 7043, 3371, 5341, 5054, 4283, 719, 713, 50507, 712, 714, 4628, 9332, 891, 4064, 7097, 1536, 7057 ],
"List Total" : 478,
"Pop Hits" : 530,
"Pop Total" : 13528,
"Fold Enrichment" : 3.257314281,
"Bonferroni" : 1.91E-12,
"Benjamini" : 9.53E-13,
"FDR" : 1.19E-12
},
{
"Cluster" : 1,
"name" : "GO:0006952~defense response",
"Term 1" : "GO:0006952",
"Term 2" : "defense response",
"size" : 60,
"%" : 10.25641026,
"PValue" : 1.79E-12,
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"List Total" : 478,
"Pop Hits" : 615,
"Pop Total" : 13528,
"Fold Enrichment" : 2.761098071,
"Bonferroni" : 5.12E-9,
"Benjamini" : 8.53E-10,
"FDR" : 3.2E-9
},
{
"Cluster" : 1,
"name" : "GO:0006954~inflammatory response",
"Term 1" : "GO:0006954",
"Term 2" : "inflammatory response",
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"List Total" : 478,
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"Pop Total" : 13528,
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"Bonferroni" : 1.3E-8,
"Benjamini" : 1.86E-9,
"FDR" : 8.15E-9
},
{
"Cluster" : 2,
"name" : "GO:0016477~cell migration",
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"Term 2" : "cell migration",
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"%" : 5.299145299,
"PValue" : 4.25E-8,
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"List Total" : 478,
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"Pop Total" : 13528,
"Fold Enrichment" : 3.178764174,
"Bonferroni" : 1.22E-4,
"Benjamini" : 6.4E-6,
"FDR" : 7.62E-5
},
{
"Cluster" : 2,
"name" : "GO:0006928~cell motion",
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"Term 2" : "cell motion",
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"%" : 7.179487179,
"PValue" : 1.08E-7,
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"List Total" : 478,
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"Pop Total" : 13528,
"Fold Enrichment" : 2.502426778,
"Bonferroni" : 3.09E-4,
"Benjamini" : 1.29E-5,
"FDR" : 1.93E-4
},
{
"Cluster" : 2,
"name" : "GO:0051674~localization of cell",
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"Term 2" : "localization of cell",
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"PValue" : 1.37E-7,
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"List Total" : 478,
"Pop Hits" : 307,
"Pop Total" : 13528,
"Fold Enrichment" : 2.949967972,
"Bonferroni" : 3.92E-4,
"Benjamini" : 1.57E-5,
"FDR" : 2.45E-4
},
{
"Cluster" : 2,
"name" : "GO:0048870~cell motility",
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"Term 2" : "cell motility",
"size" : 32,
"%" : 5.47008547,
"PValue" : 1.37E-7,
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"List Total" : 478,
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"Pop Total" : 13528,
"Fold Enrichment" : 2.949967972,
"Bonferroni" : 3.92E-4,
"Benjamini" : 1.57E-5,
"FDR" : 2.45E-4
},
{
"Cluster" : 3,
"name" : "GO:0022402~cell cycle process",
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"Term 2" : "cell cycle process",
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"PValue" : 1.71E-9,
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"List Total" : 478,
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"Pop Total" : 13528,
"Fold Enrichment" : 2.554626578,
"Bonferroni" : 4.88E-6,
"Benjamini" : 4.88E-7,
"FDR" : 3.06E-6
},
{
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"name" : "GO:0000278~mitotic cell cycle",
"Term 1" : "GO:0000278",
"Term 2" : "mitotic cell cycle",
"size" : 39,
"%" : 6.666666667,
"PValue" : 3.15E-9,
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"List Total" : 478,
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"Pop Total" : 13528,
"Fold Enrichment" : 2.983105281,
"Bonferroni" : 9.02E-6,
"Benjamini" : 6.94E-7,
"FDR" : 5.65E-6
},
{
"Cluster" : 3,
"name" : "GO:0007049~cell cycle",
"Term 1" : "GO:0007049",
"Term 2" : "cell cycle",
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"%" : 9.914529915,
"PValue" : 9.82E-8,
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"List Total" : 478,
"Pop Hits" : 776,
"Pop Total" : 13528,
"Fold Enrichment" : 2.115300004,
"Bonferroni" : 2.81E-4,
"Benjamini" : 1.22E-5,
"FDR" : 1.76E-4
},
{
"Cluster" : 3,
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"Term 1" : "GO:0007067",
"Term 2" : "mitosis",
"size" : 26,
"%" : 4.444444444,
"PValue" : 2.48E-7,
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"List Total" : 478,
"Pop Hits" : 220,
"Pop Total" : 13528,
"Fold Enrichment" : 3.3446938,
"Bonferroni" : 7.09E-4,
"Benjamini" : 2.63E-5,
"FDR" : 4.44E-4
},
{
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"Term 2" : "nuclear division",
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"List Total" : 478,
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"Pop Total" : 13528,
"Fold Enrichment" : 3.3446938,
"Bonferroni" : 7.09E-4,
"Benjamini" : 2.63E-5,
"FDR" : 4.44E-4
},
{
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"name" : "GO:0000087~M phase of mitotic cell cycle",
"Term 1" : "GO:0000087",
"Term 2" : "M phase of mitotic cell cycle",
"size" : 26,
"%" : 4.444444444,
"PValue" : 3.5E-7,
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"List Total" : 478,
"Pop Hits" : 224,
"Pop Total" : 13528,
"Fold Enrichment" : 3.284967125,
"Bonferroni" : 0.001002367,
"Benjamini" : 3.34E-5,
"FDR" : 6.28E-4
},
{
"Cluster" : 3,
"name" : "GO:0048285~organelle fission",
"Term 1" : "GO:0048285",
"Term 2" : "organelle fission",
"size" : 26,
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"PValue" : 5.33E-7,
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"List Total" : 478,
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"Pop Total" : 13528,
"Fold Enrichment" : 3.213242952,
"Bonferroni" : 0.001522916,
"Benjamini" : 4.76E-5,
"FDR" : 9.54E-4
},
{
"Cluster" : 3,
"name" : "GO:0022403~cell cycle phase",
"Term 1" : "GO:0022403",
"Term 2" : "cell cycle phase",
"size" : 37,
"%" : 6.324786325,
"PValue" : 5.58E-7,
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"List Total" : 478,
"Pop Hits" : 414,
"Pop Total" : 13528,
"Fold Enrichment" : 2.529339236,
"Bonferroni" : 0.001595571,
"Benjamini" : 4.84E-5,
"FDR" : 9.99E-4
},
{
"Cluster" : 3,
"name" : "GO:0000279~M phase",
"Term 1" : "GO:0000279",
"Term 2" : "M phase",
"size" : 32,
"%" : 5.47008547,
"PValue" : 6.34E-7,
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"List Total" : 478,
"Pop Hits" : 329,
"Pop Total" : 13528,
"Fold Enrichment" : 2.752705676,
"Bonferroni" : 0.001811476,
"Benjamini" : 5.33E-5,
"FDR" : 0.001134764
},
{
"Cluster" : 3,
"name" : "GO:0051301~cell division",
"Term 1" : "GO:0051301",
"Term 2" : "cell division",
"size" : 24,
"%" : 4.102564103,
"PValue" : 3.2E-4,
"imports" : [ 2054, 699, 23397, 4739, 332, 10403, 54443, 983, 57405, 1021, 55165, 9133, 10459, 83540, 990, 5347, 991, 9493, 4628, 701, 891, 10783, 1164, 259266 ],
"List Total" : 478,
"Pop Hits" : 295,
"Pop Total" : 13528,
"Fold Enrichment" : 2.302475002,
"Bonferroni" : 0.599673471,
"Benjamini" : 0.007998322,
"FDR" : 0.571326469
},
{
"Cluster" : 4,
"name" : "GO:0006935~chemotaxis",
"Term 1" : "GO:0006935",
"Term 2" : "chemotaxis",
"size" : 22,
"%" : 3.760683761,
"PValue" : 2.05E-7,
"imports" : [ 3627, 5880, 3672, 6288, 2919, 1230, 4283, 10563, 6352, 10371, 719, 6351, 3458, 6364, 3491, 8828, 6373, 7852, 3553, 5329, 5328, 3576 ],
"List Total" : 478,
"Pop Hits" : 160,
"Pop Total" : 13528,
"Fold Enrichment" : 3.891422594,
"Bonferroni" : 5.86E-4,
"Benjamini" : 2.26E-5,
"FDR" : 3.67E-4
},
{
"Cluster" : 4,
"name" : "GO:0042330~taxis",
"Term 1" : "GO:0042330",
"Term 2" : "taxis",
"size" : 22,
"%" : 3.760683761,
"PValue" : 2.05E-7,
"imports" : [ 3627, 5880, 3672, 6288, 2919, 1230, 4283, 10563, 6352, 10371, 719, 6351, 3458, 6364, 3491, 8828, 6373, 7852, 3553, 5329, 5328, 3576 ],
"List Total" : 478,
"Pop Hits" : 160,
"Pop Total" : 13528,
"Fold Enrichment" : 3.891422594,
"Bonferroni" : 5.86E-4,
"Benjamini" : 2.26E-5,
"FDR" : 3.67E-4
},
{
"Cluster" : 4,
"name" : "GO:0007626~locomotory behavior",
"Term 1" : "GO:0007626",
"Term 2" : "locomotory behavior",
"size" : 27,
"%" : 4.615384615,
"PValue" : 4.51E-6,
"imports" : [ 3627, 6288, 2919, 1230, 10563, 6352, 6351, 3458, 6373, 7852, 3553, 3236, 3074, 5329, 3073, 3576, 5328, 5880, 3672, 6648, 793, 4283, 10371, 6364, 719, 3491, 8828 ],
"List Total" : 478,
"Pop Hits" : 274,
"Pop Total" : 13528,
"Fold Enrichment" : 2.788809822,
"Bonferroni" : 0.01281901,
"Benjamini" : 2.43E-4,
"FDR" : 0.008074527
},
{
"Cluster" : 4,
"name" : "GO:0007610~behavior",
"Term 1" : "GO:0007610",
"Term 2" : "behavior",
"size" : 35,
"%" : 5.982905983,
"PValue" : 5.62E-5,
"imports" : [ 3627, 6288, 2919, 1230, 5008, 3620, 6352, 10563, 6351, 3458, 6373, 3678, 7852, 3553, 3236, 3074, 4233, 5329, 100, 5328, 3576, 3073, 3251, 5880, 3672, 6648, 5743, 793, 4283, 719, 6364, 10371, 3491, 8828, 2182 ],
"List Total" : 478,
"Pop Hits" : 469,
"Pop Total" : 13528,
"Fold Enrichment" : 2.112033972,
"Bonferroni" : 0.148522663,
"Benjamini" : 0.001982999,
"FDR" : 0.100577668
},
{
"Cluster" : 5,
"name" : "GO:0032963~collagen metabolic process",
"Term 1" : "GO:0032963",
"Term 2" : "collagen metabolic process",
"size" : 9,
"%" : 1.538461538,
"PValue" : 3.76E-6,
"imports" : [ 4314, 9697, 4312, 4319, 4318, 4316, 871, 4322, 4320 ],
"List Total" : 478,
"Pop Hits" : 28,
"Pop Total" : 13528,
"Fold Enrichment" : 9.096832038,
"Bonferroni" : 0.010696499,
"Benjamini" : 2.15E-4,
"FDR" : 0.006730413
},
{
"Cluster" : 5,
"name" : "GO:0044236~multicellular organismal metabolic process",
"Term 1" : "GO:0044236",
"Term 2" : "multicellular organismal metabolic process",
"size" : 10,
"%" : 1.709401709,
"PValue" : 4.03E-6,
"imports" : [ 4314, 9697, 4331, 4312, 4319, 4318, 4316, 871, 4322, 4320 ],
"List Total" : 478,
"Pop Hits" : 37,
"Pop Total" : 13528,
"Fold Enrichment" : 7.6489879,
"Bonferroni" : 0.011462875,
"Benjamini" : 2.26E-4,
"FDR" : 0.007215402
},
{
"Cluster" : 5,
"name" : "GO:0044259~multicellular organismal macromolecule metabolic process",
"Term 1" : "GO:0044259",
"Term 2" : "multicellular organismal macromolecule metabolic process",
"size" : 9,
"%" : 1.538461538,
"PValue" : 8.69E-6,
"imports" : [ 4314, 9697, 4312, 4319, 4318, 4316, 871, 4322, 4320 ],
"List Total" : 478,
"Pop Hits" : 31,
"Pop Total" : 13528,
"Fold Enrichment" : 8.216493454,
"Bonferroni" : 0.024558388,
"Benjamini" : 3.77E-4,
"FDR" : 0.015560939
},
{
"Cluster" : 5,
"name" : "GO:0030574~collagen catabolic process",
"Term 1" : "GO:0030574",
"Term 2" : "collagen catabolic process",
"size" : 7,
"%" : 1.196581197,
"PValue" : 4.73E-5,
"imports" : [ 4314, 4312, 4319, 4318, 4316, 4322, 4320 ],
"List Total" : 478,
"Pop Hits" : 20,
"Pop Total" : 13528,
"Fold Enrichment" : 9.905439331,
"Bonferroni" : 0.126729404,
"Benjamini" : 0.001713844,
"FDR" : 0.084775068
},
{
"Cluster" : 5,
"name" : "GO:0044243~multicellular organismal catabolic process",
"Term 1" : "GO:0044243",
"Term 2" : "multicellular organismal catabolic process",
"size" : 7,
"%" : 1.196581197,
"PValue" : 2.35E-4,
"imports" : [ 4314, 4312, 4319, 4318, 4316, 4322, 4320 ],
"List Total" : 478,
"Pop Hits" : 26,
"Pop Total" : 13528,
"Fold Enrichment" : 7.619568716,
"Bonferroni" : 0.48950453,
"Benjamini" : 0.006206341,
"FDR" : 0.419931728
},
{
"Cluster" : 6,
"name" : "GO:0001817~regulation of cytokine production",
"Term 1" : "GO:0001817",
"Term 2" : "regulation of cytokine production",
"size" : 21,
"%" : 3.58974359,
"PValue" : 6.09E-6,
"imports" : [ 941, 6288, 5588, 942, 8767, 3620, 834, 24145, 3624, 80381, 5552, 929, 1051, 3458, 7040, 2207, 3659, 3553, 7097, 23586, 7057 ],
"List Total" : 478,
"Pop Hits" : 181,
"Pop Total" : 13528,
"Fold Enrichment" : 3.283571049,
"Bonferroni" : 0.017265117,
"Benjamini" : 3.11E-4,
"FDR" : 0.010899429
},
{
"Cluster" : 6,
"name" : "GO:0051240~positive regulation of multicellular organismal process",
"Term 1" : "GO:0051240",
"Term 2" : "positive regulation of multicellular organismal process",
"size" : 24,
"%" : 4.102564103,
"PValue" : 1.78E-5,
"imports" : [ 6288, 760, 5743, 3084, 8767, 3620, 857, 834, 24145, 80381, 929, 6352, 7040, 3458, 7168, 6696, 2207, 10468, 3553, 7097, 23586, 100, 7057, 7043 ],
"List Total" : 478,
"Pop Hits" : 244,
"Pop Total" : 13528,
"Fold Enrichment" : 2.783730023,
"Bonferroni" : 0.04977932,
"Benjamini" : 7.09E-4,
"FDR" : 0.031952269
},
{
"Cluster" : 6,
"name" : "GO:0001819~positive regulation of cytokine production",
"Term 1" : "GO:0001819",
"Term 2" : "positive regulation of cytokine production",
"size" : 13,
"%" : 2.222222222,
"PValue" : 7.24E-5,
"imports" : [ 6288, 8767, 3620, 834, 24145, 929, 3458, 7040, 2207, 3553, 7097, 7057, 23586 ],
"List Total" : 478,
"Pop Hits" : 90,
"Pop Total" : 13528,
"Fold Enrichment" : 4.087959089,
"Bonferroni" : 0.187162326,
"Benjamini" : 0.002434958,
"FDR" : 0.129610357
},
{
"Cluster" : 7,
"name" : "GO:0042129~regulation of T cell proliferation",
"Term 1" : "GO:0042129",
"Term 2" : "regulation of T cell proliferation",
"size" : 16,
"%" : 2.735042735,
"PValue" : 2.64E-9,
"imports" : [ 941, 5588, 29126, 10673, 80380, 8767, 868, 3620, 641, 80381, 3458, 7040, 3553, 3559, 5788, 1493 ],
"List Total" : 478,
"Pop Hits" : 62,
"Pop Total" : 13528,
"Fold Enrichment" : 7.303549737,
"Bonferroni" : 7.54E-6,
"Benjamini" : 6.86E-7,
"FDR" : 4.72E-6
},
{
"Cluster" : 7,
"name" : "GO:0050863~regulation of T cell activation",
"Term 1" : "GO:0050863",
"Term 2" : "regulation of T cell activation",
"size" : 21,
"%" : 3.58974359,
"PValue" : 4.24E-9,
"imports" : [ 941, 5588, 942, 29126, 10673, 80380, 8767, 914, 868, 3620, 641, 80381, 55824, 3458, 7040, 3553, 3559, 100, 3575, 5788, 1493 ],
"List Total" : 478,
"Pop Hits" : 117,
"Pop Total" : 13528,
"Fold Enrichment" : 5.079712477,
"Bonferroni" : 1.21E-5,
"Benjamini" : 8.66E-7,
"FDR" : 7.59E-6
},
{
"Cluster" : 7,
"name" : "GO:0050865~regulation of cell activation",
"Term 1" : "GO:0050865",
"Term 2" : "regulation of cell activation",
"size" : 25,
"%" : 4.273504274,
"PValue" : 1.15E-8,
"imports" : [ 941, 942, 29126, 80380, 8767, 10673, 868, 3620, 80381, 641, 3624, 7040, 3458, 10630, 3553, 3559, 100, 3575, 5588, 914, 5341, 55824, 7057, 5788, 1493 ],
"List Total" : 478,
"Pop Hits" : 175,
"Pop Total" : 13528,
"Fold Enrichment" : 4.043036461,
"Bonferroni" : 3.3E-5,
"Benjamini" : 2.06E-6,
"FDR" : 2.07E-5
},
{
"Cluster" : 7,
"name" : "GO:0050670~regulation of lymphocyte proliferation",
"Term 1" : "GO:0050670",
"Term 2" : "regulation of lymphocyte proliferation",
"size" : 17,
"%" : 2.905982906,
"PValue" : 2.6E-8,
"imports" : [ 941, 5588, 29126, 10673, 80380, 8767, 868, 3620, 641, 80381, 3458, 7040, 3553, 3559, 5788, 100, 1493 ],
"List Total" : 478,
"Pop Hits" : 83,
"Pop Total" : 13528,
"Fold Enrichment" : 5.796642637,
"Bonferroni" : 7.45E-5,
"Benjamini" : 4.38E-6,
"FDR" : 4.66E-5
},
{
"Cluster" : 7,
"name" : "GO:0032944~regulation of mononuclear cell proliferation",
"Term 1" : "GO:0032944",
"Term 2" : "regulation of mononuclear cell proliferation",
"size" : 17,
"%" : 2.905982906,
"PValue" : 3.11E-8,
"imports" : [ 941, 5588, 29126, 10673, 80380, 8767, 868, 3620, 641, 80381, 3458, 7040, 3553, 3559, 5788, 100, 1493 ],
"List Total" : 478,
"Pop Hits" : 84,
"Pop Total" : 13528,
"Fold Enrichment" : 5.727634987,
"Bonferroni" : 8.91E-5,
"Benjamini" : 4.95E-6,
"FDR" : 5.58E-5
},
{
"Cluster" : 7,
"name" : "GO:0070663~regulation of leukocyte proliferation",
"Term 1" : "GO:0070663",
"Term 2" : "regulation of leukocyte proliferation",
"size" : 17,
"%" : 2.905982906,
"PValue" : 3.11E-8,
"imports" : [ 941, 5588, 29126, 10673, 80380, 8767, 868, 3620, 641, 80381, 3458, 7040, 3553, 3559, 5788, 100, 1493 ],
"List Total" : 478,
"Pop Hits" : 84,
"Pop Total" : 13528,
"Fold Enrichment" : 5.727634987,
"Bonferroni" : 8.91E-5,
"Benjamini" : 4.95E-6,
"FDR" : 5.58E-5
},
{
"Cluster" : 7,
"name" : "GO:0051249~regulation of lymphocyte activation",
"Term 1" : "GO:0051249",
"Term 2" : "regulation of lymphocyte activation",
"size" : 22,
"%" : 3.760683761,
"PValue" : 5.25E-8,
"imports" : [ 941, 5588, 942, 29126, 10673, 80380, 8767, 914, 868, 3620, 3624, 641, 80381, 55824, 3458, 7040, 3553, 3559, 100, 3575, 5788, 1493 ],
"List Total" : 478,
"Pop Hits" : 148,
"Pop Total" : 13528,
"Fold Enrichment" : 4.206943345,
"Bonferroni" : 1.5E-4,
"Benjamini" : 7.51E-6,
"FDR" : 9.41E-5
},
{
"Cluster" : 7,
"name" : "GO:0050867~positive regulation of cell activation",
"Term 1" : "GO:0050867",
"Term 2" : "positive regulation of cell activation",
"size" : 19,
"%" : 3.247863248,
"PValue" : 5.92E-8,
"imports" : [ 941, 5588, 942, 10673, 80380, 8767, 914, 5341, 641, 80381, 3458, 7040, 10630, 3553, 3559, 100, 3575, 5788, 7057 ],
"List Total" : 478,
"Pop Hits" : 111,
"Pop Total" : 13528,
"Fold Enrichment" : 4.844359003,
"Bonferroni" : 1.69E-4,
"Benjamini" : 8.07E-6,
"FDR" : 1.06E-4
},
{
"Cluster" : 7,
"name" : "GO:0002694~regulation of leukocyte activation",
"Term 1" : "GO:0002694",
"Term 2" : "regulation of leukocyte activation",
"size" : 23,
"%" : 3.931623932,
"PValue" : 8.82E-8,
"imports" : [ 941, 5588, 942, 29126, 10673, 80380, 8767, 914, 868, 3620, 3624, 641, 80381, 55824, 3458, 7040, 3553, 3559, 100, 3575, 5788, 7057, 1493 ],
"List Total" : 478,
"Pop Hits" : 166,
"Pop Total" : 13528,
"Fold Enrichment" : 3.921258255,
"Bonferroni" : 2.52E-4,
"Benjamini" : 1.15E-5,
"FDR" : 1.58E-4
},
{
"Cluster" : 7,
"name" : "GO:0002684~positive regulation of immune system process",
"Term 1" : "GO:0002684",
"Term 2" : "positive regulation of immune system process",
"size" : 27,
"%" : 4.615384615,
"PValue" : 3.11E-7,
"imports" : [ 941, 942, 10673, 8767, 80380, 868, 3620, 80381, 641, 3383, 7040, 3458, 2207, 3553, 3559, 629, 3575, 100, 5588, 914, 719, 713, 712, 714, 7097, 7057, 5788 ],
"List Total" : 478,
"Pop Hits" : 238,
"Pop Total" : 13528,
"Fold Enrichment" : 3.210646602,
"Bonferroni" : 8.89E-4,
"Benjamini" : 3.18E-5,
"FDR" : 5.57E-4
},
{
"Cluster" : 7,
"name" : "GO:0042102~positive regulation of T cell proliferation",
"Term 1" : "GO:0042102",
"Term 2" : "positive regulation of T cell proliferation",
"size" : 11,
"%" : 1.88034188,
"PValue" : 6.85E-7,
"imports" : [ 3458, 941, 5588, 10673, 80380, 8767, 3553, 3559, 5788, 80381, 641 ],
"List Total" : 478,
"Pop Hits" : 39,
"Pop Total" : 13528,
"Fold Enrichment" : 7.982405321,
"Bonferroni" : 0.001958459,
"Benjamini" : 5.6E-5,
"FDR" : 0.001226928
},
{
"Cluster" : 7,
"name" : "GO:0002696~positive regulation of leukocyte activation",
"Term 1" : "GO:0002696",
"Term 2" : "positive regulation of leukocyte activation",
"size" : 17,
"%" : 2.905982906,
"PValue" : 8.8E-7,
"imports" : [ 941, 5588, 942, 10673, 80380, 8767, 914, 641, 80381, 3458, 7040, 3553, 3559, 100, 3575, 5788, 7057 ],
"List Total" : 478,
"Pop Hits" : 106,
"Pop Total" : 13528,
"Fold Enrichment" : 4.538880556,
"Bonferroni" : 0.002514854,
"Benjamini" : 6.81E-5,
"FDR" : 0.001575932
},
{
"Cluster" : 7,
"name" : "GO:0002683~negative regulation of immune system process",
"Term 1" : "GO:0002683",
"Term 2" : "negative regulation of immune system process",
"size" : 15,
"%" : 2.564102564,
"PValue" : 1.08E-6,
"imports" : [ 29126, 80380, 868, 3620, 26585, 80381, 3624, 55824, 7040, 3559, 5788, 7057, 3575, 100, 1493 ],
"List Total" : 478,
"Pop Hits" : 83,
"Pop Total" : 13528,
"Fold Enrichment" : 5.11468468,
"Bonferroni" : 0.003082344,
"Benjamini" : 8.12E-5,
"FDR" : 0.001932096
},
{
"Cluster" : 7,
"name" : "GO:0050870~positive regulation of T cell activation",
"Term 1" : "GO:0050870",
"Term 2" : "positive regulation of T cell activation",
"size" : 14,
"%" : 2.393162393,
"PValue" : 2.22E-6,
"imports" : [ 941, 5588, 942, 10673, 8767, 80380, 641, 80381, 3458, 3553, 3559, 5788, 3575, 100 ],
"List Total" : 478,
"Pop Hits" : 76,
"Pop Total" : 13528,
"Fold Enrichment" : 5.213389121,
"Bonferroni" : 0.006331745,
"Benjamini" : 1.41E-4,
"FDR" : 0.003975346
},
{
"Cluster" : 7,
"name" : "GO:0050671~positive regulation of lymphocyte proliferation",
"Term 1" : "GO:0050671",
"Term 2" : "positive regulation of lymphocyte proliferation",
"size" : 12,
"%" : 2.051282051,
"PValue" : 2.74E-6,
"imports" : [ 3458, 941, 5588, 10673, 80380, 8767, 3553, 3559, 100, 5788, 80381, 641 ],
"List Total" : 478,
"Pop Hits" : 55,
"Pop Total" : 13528,
"Fold Enrichment" : 6.174819323,
"Bonferroni" : 0.007817452,
"Benjamini" : 1.71E-4,
"FDR" : 0.004911784
},
{
"Cluster" : 7,
"name" : "GO:0032946~positive regulation of mononuclear cell proliferation",
"Term 1" : "GO:0032946",
"Term 2" : "positive regulation of mononuclear cell proliferation",
"size" : 12,
"%" : 2.051282051,
"PValue" : 3.31E-6,
"imports" : [ 3458, 941, 5588, 10673, 80380, 8767, 3553, 3559, 100, 5788, 80381, 641 ],
"List Total" : 478,
"Pop Hits" : 56,
"Pop Total" : 13528,
"Fold Enrichment" : 6.064554692,
"Bonferroni" : 0.009415861,
"Benjamini" : 1.97E-4,
"FDR" : 0.005920814
},
{
"Cluster" : 7,
"name" : "GO:0070665~positive regulation of leukocyte proliferation",
"Term 1" : "GO:0070665",
"Term 2" : "positive regulation of leukocyte proliferation",
"size" : 12,
"%" : 2.051282051,
"PValue" : 3.31E-6,
"imports" : [ 3458, 941, 5588, 10673, 80380, 8767, 3553, 3559, 100, 5788, 80381, 641 ],
"List Total" : 478,
"Pop Hits" : 56,
"Pop Total" : 13528,
"Fold Enrichment" : 6.064554692,
"Bonferroni" : 0.009415861,
"Benjamini" : 1.97E-4,
"FDR" : 0.005920814
},
{
"Cluster" : 7,
"name" : "GO:0051251~positive regulation of lymphocyte activation",
"Term 1" : "GO:0051251",
"Term 2" : "positive regulation of lymphocyte activation",
"size" : 15,
"%" : 2.564102564,
"PValue" : 7.26E-6,
"imports" : [ 941, 5588, 942, 10673, 80380, 8767, 641, 80381, 3458, 7040, 3553, 3559, 5788, 3575, 100 ],
"List Total" : 478,
"Pop Hits" : 97,
"Pop Total" : 13528,
"Fold Enrichment" : 4.376482768,
"Bonferroni" : 0.020570637,
"Benjamini" : 3.52E-4,
"FDR" : 0.013007885
},
{
"Cluster" : 7,
"name" : "GO:0002822~regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains",
"Term 1" : "GO:0002822",
"Term 2" : "regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains",
"size" : 11,
"%" : 1.88034188,
"PValue" : 1.9E-5,
"imports" : [ 3458, 7040, 941, 942, 10673, 2207, 3553, 3620, 100, 3575, 5788 ],
"List Total" : 478,
"Pop Hits" : 55,
"Pop Total" : 13528,
"Fold Enrichment" : 5.660251046,
"Bonferroni" : 0.052912321,
"Benjamini" : 7.44E-4,
"FDR" : 0.034018559
},
{
"Cluster" : 7,
"name" : "GO:0002819~regulation of adaptive immune response",
"Term 1" : "GO:0002819",
"Term 2" : "regulation of adaptive immune response",
"size" : 11,
"%" : 1.88034188,
"PValue" : 2.24E-5,
"imports" : [ 3458, 7040, 941, 942, 10673, 2207, 3553, 3620, 100, 3575, 5788 ],
"List Total" : 478,
"Pop Hits" : 56,
"Pop Total" : 13528,
"Fold Enrichment" : 5.559175134,
"Bonferroni" : 0.062112476,
"Benjamini" : 8.66E-4,
"FDR" : 0.040125778
},
{
"Cluster" : 7,
"name" : "GO:0042130~negative regulation of T cell proliferation",
"Term 1" : "GO:0042130",
"Term 2" : "negative regulation of T cell proliferation",
"size" : 8,
"%" : 1.367521368,
"PValue" : 3.12E-5,
"imports" : [ 7040, 29126, 80380, 868, 3620, 3559, 80381, 1493 ],
"List Total" : 478,
"Pop Hits" : 27,
"Pop Total" : 13528,
"Fold Enrichment" : 8.385557105,
"Bonferroni" : 0.08535167,
"Benjamini" : 0.001188834,
"FDR" : 0.055821467
},
{
"Cluster" : 7,
"name" : "GO:0050868~negative regulation of T cell activation",
"Term 1" : "GO:0050868",
"Term 2" : "negative regulation of T cell activation",
"size" : 9,
"%" : 1.538461538,
"PValue" : 9.24E-5,
"imports" : [ 55824, 7040, 29126, 80380, 868, 3620, 3559, 80381, 1493 ],
"List Total" : 478,
"Pop Hits" : 42,
"Pop Total" : 13528,
"Fold Enrichment" : 6.064554692,
"Bonferroni" : 0.232449321,
"Benjamini" : 0.00290293,
"FDR" : 0.165436412
},
{
"Cluster" : 7,
"name" : "GO:0051250~negative regulation of lymphocyte activation",
"Term 1" : "GO:0051250",
"Term 2" : "negative regulation of lymphocyte activation",
"size" : 10,
"%" : 1.709401709,
"PValue" : 1.01E-4,
"imports" : [ 55824, 7040, 29126, 80380, 868, 3620, 3559, 80381, 3624, 1493 ],
"List Total" : 478,
"Pop Hits" : 54,
"Pop Total" : 13528,
"Fold Enrichment" : 5.240973191,
"Bonferroni" : 0.251294851,
"Benjamini" : 0.003107099,
"FDR" : 0.180968039
},
{
"Cluster" : 7,
"name" : "GO:0032945~negative regulation of mononuclear cell proliferation",
"Term 1" : "GO:0032945",
"Term 2" : "negative regulation of mononuclear cell proliferation",
"size" : 8,
"%" : 1.367521368,
"PValue" : 1.01E-4,
"imports" : [ 7040, 29126, 80380, 868, 3620, 3559, 80381, 1493 ],
"List Total" : 478,
"Pop Hits" : 32,
"Pop Total" : 13528,
"Fold Enrichment" : 7.075313808,
"Bonferroni" : 0.251910694,
"Benjamini" : 0.003082823,
"FDR" : 0.18148212
},
{
"Cluster" : 7,
"name" : "GO:0050672~negative regulation of lymphocyte proliferation",
"Term 1" : "GO:0050672",
"Term 2" : "negative regulation of lymphocyte proliferation",
"size" : 8,
"%" : 1.367521368,
"PValue" : 1.01E-4,
"imports" : [ 7040, 29126, 80380, 868, 3620, 3559, 80381, 1493 ],
"List Total" : 478,
"Pop Hits" : 32,
"Pop Total" : 13528,
"Fold Enrichment" : 7.075313808,
"Bonferroni" : 0.251910694,
"Benjamini" : 0.003082823,
"FDR" : 0.18148212
},
{
"Cluster" : 7,
"name" : "GO:0070664~negative regulation of leukocyte proliferation",
"Term 1" : "GO:0070664",
"Term 2" : "negative regulation of leukocyte proliferation",
"size" : 8,
"%" : 1.367521368,
"PValue" : 1.01E-4,
"imports" : [ 7040, 29126, 80380, 868, 3620, 3559, 80381, 1493 ],
"List Total" : 478,
"Pop Hits" : 32,
"Pop Total" : 13528,
"Fold Enrichment" : 7.075313808,
"Bonferroni" : 0.251910694,
"Benjamini" : 0.003082823,
"FDR" : 0.18148212
},
{
"Cluster" : 7,
"name" : "GO:0002695~negative regulation of leukocyte activation",
"Term 1" : "GO:0002695",
"Term 2" : "negative regulation of leukocyte activation",
"size" : 10,
"%" : 1.709401709,
"PValue" : 1.56E-4,
"imports" : [ 55824, 7040, 29126, 80380, 868, 3620, 3559, 80381, 3624, 1493 ],
"List Total" : 478,
"Pop Hits" : 57,
"Pop Total" : 13528,
"Fold Enrichment" : 4.965132497,
"Bonferroni" : 0.359721289,
"Benjamini" : 0.004539174,
"FDR" : 0.278654593
},
{
"Cluster" : 7,
"name" : "GO:0050866~negative regulation of cell activation",
"Term 1" : "GO:0050866",
"Term 2" : "negative regulation of cell activation",
"size" : 10,
"%" : 1.709401709,
"PValue" : 2.65E-4,
"imports" : [ 55824, 7040, 29126, 80380, 868, 3620, 3559, 80381, 3624, 1493 ],
"List Total" : 478,
"Pop Hits" : 61,
"Pop Total" : 13528,
"Fold Enrichment" : 4.639550038,
"Bonferroni" : 0.53173771,
"Benjamini" : 0.006936625,
"FDR" : 0.473735776
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{
"Cluster" : 7,
"name" : "GO:0046640~regulation of alpha-beta T cell proliferation",
"Term 1" : "GO:0046640",
"Term 2" : "regulation of alpha-beta T cell proliferation",
"size" : 5,
"%" : 0.854700855,
"PValue" : 8.47E-4,
"imports" : [ 941, 8767, 868, 5788, 641 ],
"List Total" : 478,
"Pop Hits" : 13,
"Pop Total" : 13528,
"Fold Enrichment" : 10.88509817,
"Bonferroni" : 0.911472958,
"Benjamini" : 0.017168394,
"FDR" : 1.505925585
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{
"Cluster" : 7,
"name" : "GO:0046634~regulation of alpha-beta T cell activation",
"Term 1" : "GO:0046634",
"Term 2" : "regulation of alpha-beta T cell activation",
"size" : 7,
"%" : 1.196581197,
"PValue" : 0.00147461,
"imports" : [ 941, 942, 8767, 868, 100, 5788, 641 ],
"List Total" : 478,
"Pop Hits" : 36,
"Pop Total" : 13528,
"Fold Enrichment" : 5.50302185,
"Bonferroni" : 0.985351946,
"Benjamini" : 0.026212883,
"FDR" : 2.608683881
},
{
"Cluster" : 7,
"name" : "GO:0045619~regulation of lymphocyte differentiation",
"Term 1" : "GO:0045619",
"Term 2" : "regulation of lymphocyte differentiation",
"size" : 9,
"%" : 1.538461538,
"PValue" : 0.001588902,
"imports" : [ 941, 942, 914, 3559, 100, 3575, 5788, 3624, 1493 ],
"List Total" : 478,
"Pop Hits" : 63,
"Pop Total" : 13528,
"Fold Enrichment" : 4.043036461,
"Bonferroni" : 0.989443936,
"Benjamini" : 0.027871636,
"FDR" : 2.808168688
},
{
"Cluster" : 7,
"name" : "GO:0046635~positive regulation of alpha-beta T cell activation",
"Term 1" : "GO:0046635",
"Term 2" : "positive regulation of alpha-beta T cell activation",
"size" : 6,
"%" : 1.025641026,
"PValue" : 0.001900029,
"imports" : [ 941, 942, 8767, 100, 5788, 641 ],
"List Total" : 478,
"Pop Hits" : 26,
"Pop Total" : 13528,
"Fold Enrichment" : 6.531058899,
"Bonferroni" : 0.995673751,
"Benjamini" : 0.031510819,
"FDR" : 3.349252208
},
{
"Cluster" : 7,
"name" : "GO:0045580~regulation of T cell differentiation",
"Term 1" : "GO:0045580",
"Term 2" : "regulation of T cell differentiation",
"size" : 8,
"%" : 1.367521368,
"PValue" : 0.001958653,
"imports" : [ 941, 942, 914, 3559, 100, 3575, 5788, 1493 ],
"List Total" : 478,
"Pop Hits" : 51,
"Pop Total" : 13528,
"Fold Enrichment" : 4.439412585,
"Bonferroni" : 0.996343183,
"Benjamini" : 0.032096645,
"FDR" : 3.450887841
},
{
"Cluster" : 7,
"name" : "GO:0046641~positive regulation of alpha-beta T cell proliferation",
"Term 1" : "GO:0046641",
"Term 2" : "positive regulation of alpha-beta T cell proliferation",
"size" : 4,
"%" : 0.683760684,
"PValue" : 0.003121725,
"imports" : [ 941, 8767, 5788, 641 ],
"List Total" : 478,
"Pop Hits" : 9,
"Pop Total" : 13528,
"Fold Enrichment" : 12.57833566,
"Bonferroni" : 0.999870049,
"Benjamini" : 0.047218293,
"FDR" : 5.44653148
},
{
"Cluster" : 7,
"name" : "GO:0032663~regulation of interleukin-2 production",
"Term 1" : "GO:0032663",
"Term 2" : "regulation of interleukin-2 production",
"size" : 6,
"%" : 1.025641026,
"PValue" : 0.003666235,
"imports" : [ 941, 942, 5588, 8767, 3553, 80381 ],
"List Total" : 478,
"Pop Hits" : 30,
"Pop Total" : 13528,
"Fold Enrichment" : 5.660251046,
"Bonferroni" : 0.999972793,
"Benjamini" : 0.053823888,
"FDR" : 6.367379926
},
{
"Cluster" : 7,
"name" : "GO:0045076~regulation of interleukin-2 biosynthetic process",
"Term 1" : "GO:0045076",
"Term 2" : "regulation of interleukin-2 biosynthetic process",
"size" : 5,
"%" : 0.854700855,
"PValue" : 0.003880665,
"imports" : [ 941, 942, 5588, 3553, 80381 ],
"List Total" : 478,
"Pop Hits" : 19,
"Pop Total" : 13528,
"Fold Enrichment" : 7.447698745,
"Bonferroni" : 0.999985306,
"Benjamini" : 0.056311072,
"FDR" : 6.727683118
},
{
"Cluster" : 7,
"name" : "GO:0042035~regulation of cytokine biosynthetic process",
"Term 1" : "GO:0042035",
"Term 2" : "regulation of cytokine biosynthetic process",
"size" : 9,
"%" : 1.538461538,
"PValue" : 0.004418362,
"imports" : [ 1051, 3458, 941, 942, 5588, 3659, 3553, 80381, 3624 ],
"List Total" : 478,
"Pop Hits" : 74,
"Pop Total" : 13528,
"Fold Enrichment" : 3.442044555,
"Bonferroni" : 0.999996867,
"Benjamini" : 0.060811861,
"FDR" : 7.625420127
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{
"Cluster" : 7,
"name" : "GO:0045582~positive regulation of T cell differentiation",
"Term 1" : "GO:0045582",
"Term 2" : "positive regulation of T cell differentiation",
"size" : 6,
"%" : 1.025641026,
"PValue" : 0.00489021,
"imports" : [ 941, 942, 3559, 100, 3575, 5788 ],
"List Total" : 478,
"Pop Hits" : 32,
"Pop Total" : 13528,
"Fold Enrichment" : 5.306485356,
"Bonferroni" : 0.999999193,
"Benjamini" : 0.065227856,
"FDR" : 8.406489196
},
{
"Cluster" : 7,
"name" : "GO:0042108~positive regulation of cytokine biosynthetic process",
"Term 1" : "GO:0042108",
"Term 2" : "positive regulation of cytokine biosynthetic process",
"size" : 7,
"%" : 1.196581197,
"PValue" : 0.006512618,
"imports" : [ 3458, 941, 942, 5588, 3659, 3553, 80381 ],
"List Total" : 478,
"Pop Hits" : 48,
"Pop Total" : 13528,
"Fold Enrichment" : 4.127266388,
"Bonferroni" : 0.999999992,
"Benjamini" : 0.082204017,
"FDR" : 11.04481272
},
{
"Cluster" : 7,
"name" : "GO:0045621~positive regulation of lymphocyte differentiation",
"Term 1" : "GO:0045621",
"Term 2" : "positive regulation of lymphocyte differentiation",
"size" : 6,
"%" : 1.025641026,
"PValue" : 0.007231062,
"imports" : [ 941, 942, 3559, 100, 3575, 5788 ],
"List Total" : 478,
"Pop Hits" : 35,
"Pop Total" : 13528,
"Fold Enrichment" : 4.851643754,
"Bonferroni" : 0.999999999,
"Benjamini" : 0.087808024,
"FDR" : 12.19005987
},
{
"Cluster" : 7,
"name" : "GO:0045086~positive regulation of interleukin-2 biosynthetic process",
"Term 1" : "GO:0045086",
"Term 2" : "positive regulation of interleukin-2 biosynthetic process",
"size" : 4,
"%" : 0.683760684,
"PValue" : 0.009568297,
"imports" : [ 941, 942, 5588, 3553 ],
"List Total" : 478,
"Pop Hits" : 13,
"Pop Total" : 13528,
"Fold Enrichment" : 8.708078532,
"Bonferroni" : 1,
"Benjamini" : 0.109181692,
"FDR" : 15.8202147
},
{
"Cluster" : 7,
"name" : "GO:0046638~positive regulation of alpha-beta T cell differentiation",
"Term 1" : "GO:0046638",
"Term 2" : "positive regulation of alpha-beta T cell differentiation",
"size" : 3,
"%" : 0.512820513,
"PValue" : 0.155616539,
"imports" : [ 941, 942, 100 ],
"List Total" : 478,
"Pop Hits" : 20,
"Pop Total" : 13528,
"Fold Enrichment" : 4.245188285,
"Bonferroni" : 1,
"Benjamini" : 0.678169745,
"FDR" : 95.16765548
},
{
"Cluster" : 7,
"name" : "GO:0046637~regulation of alpha-beta T cell differentiation",
"Term 1" : "GO:0046637",
"Term 2" : "regulation of alpha-beta T cell differentiation",
"size" : 3,
"%" : 0.512820513,
"PValue" : 0.219876449,
"imports" : [ 941, 942, 100 ],
"List Total" : 478,
"Pop Hits" : 25,
"Pop Total" : 13528,
"Fold Enrichment" : 3.396150628,
"Bonferroni" : 1,
"Benjamini" : 0.78737858,
"FDR" : 98.82942566
},
{
"Cluster" : 8,
"name" : "GO:0032101~regulation of response to external stimulus",
"Term 1" : "GO:0032101",
"Term 2" : "regulation of response to external stimulus",
"size" : 25,
"%" : 4.273504274,
"PValue" : 1.64E-9,
"imports" : [ 6288, 2167, 5008, 3620, 313, 80381, 6352, 7040, 10630, 2207, 4907, 3559, 100, 3576, 5328, 5743, 857, 26585, 5054, 5341, 7052, 9180, 6696, 50604, 7057 ],
"List Total" : 478,
"Pop Hits" : 159,
"Pop Total" : 13528,
"Fold Enrichment" : 4.449882898,
"Bonferroni" : 4.69E-6,
"Benjamini" : 5.21E-7,
"FDR" : 2.93E-6
},
{
"Cluster" : 8,
"name" : "GO:0050727~regulation of inflammatory response",
"Term 1" : "GO:0050727",
"Term 2" : "regulation of inflammatory response",
"size" : 15,
"%" : 2.564102564,
"PValue" : 3.51E-7,
"imports" : [ 2167, 6288, 5743, 5008, 313, 3620, 80381, 6352, 7052, 9180, 50604, 2207, 4907, 3559, 100 ],
"List Total" : 478,
"Pop Hits" : 76,
"Pop Total" : 13528,
"Fold Enrichment" : 5.585774059,
"Bonferroni" : 0.001005119,
"Benjamini" : 3.24E-5,
"FDR" : 6.29E-4
},
{
"Cluster" : 8,
"name" : "GO:0032103~positive regulation of response to external stimulus",
"Term 1" : "GO:0032103",
"Term 2" : "positive regulation of response to external stimulus",
"size" : 10,
"%" : 1.709401709,
"PValue" : 3.83E-4,
"imports" : [ 6352, 7040, 9180, 7052, 2167, 2207, 5008, 3620, 7057, 3576 ],
"List Total" : 478,
"Pop Hits" : 64,
"Pop Total" : 13528,
"Fold Enrichment" : 4.42207113,
"Bonferroni" : 0.666317372,
"Benjamini" : 0.009104674,
"FDR" : 0.684574944
},
{
"Cluster" : 8,
"name" : "GO:0050729~positive regulation of inflammatory response",
"Term 1" : "GO:0050729",
"Term 2" : "positive regulation of inflammatory response",
"size" : 7,
"%" : 1.196581197,
"PValue" : 5.38E-4,
"imports" : [ 6352, 9180, 7052, 2167, 2207, 5008, 3620 ],
"List Total" : 478,
"Pop Hits" : 30,
"Pop Total" : 13528,
"Fold Enrichment" : 6.60362622,
"Bonferroni" : 0.785368121,
"Benjamini" : 0.012043666,
"FDR" : 0.958479416
},
{
"Cluster" : 8,
"name" : "GO:0031349~positive regulation of defense response",
"Term 1" : "GO:0031349",
"Term 2" : "positive regulation of defense response",
"size" : 9,
"%" : 1.538461538,
"PValue" : 0.004062643,
"imports" : [ 6352, 9180, 7052, 2167, 2207, 8767, 5008, 3620, 7097 ],
"List Total" : 478,
"Pop Hits" : 73,
"Pop Total" : 13528,
"Fold Enrichment" : 3.48919585,
"Bonferroni" : 0.999991289,
"Benjamini" : 0.058288698,
"FDR" : 7.032430376
},
{
"Cluster" : 8,
"name" : "GO:0002675~positive regulation of acute inflammatory response",
"Term 1" : "GO:0002675",
"Term 2" : "positive regulation of acute inflammatory response",
"size" : 4,
"%" : 0.683760684,
"PValue" : 0.007555634,
"imports" : [ 6352, 9180, 2207, 5008 ],
"List Total" : 478,
"Pop Hits" : 12,
"Pop Total" : 13528,
"Fold Enrichment" : 9.433751743,
"Bonferroni" : 1,
"Benjamini" : 0.091193072,
"FDR" : 12.70287134
},
{
"Cluster" : 8,
"name" : "GO:0002673~regulation of acute inflammatory response",
"Term 1" : "GO:0002673",
"Term 2" : "regulation of acute inflammatory response",
"size" : 4,
"%" : 0.683760684,
"PValue" : 0.036146898,
"imports" : [ 6352, 9180, 2207, 5008 ],
"List Total" : 478,
"Pop Hits" : 21,
"Pop Total" : 13528,
"Fold Enrichment" : 5.390715282,
"Bonferroni" : 1,
"Benjamini" : 0.284306382,
"FDR" : 48.28724886
},
{
"Cluster" : 9,
"name" : "GO:0048514~blood vessel morphogenesis",
"Term 1" : "GO:0048514",
"Term 2" : "blood vessel morphogenesis",
"size" : 21,
"%" : 3.58974359,
"PValue" : 5.76E-5,
"imports" : [ 5747, 1464, 857, 10512, 285, 51330, 3676, 83605, 3491, 7052, 8828, 7424, 1490, 7852, 3553, 4691, 9474, 4323, 7057, 5328, 3576 ],
"List Total" : 478,
"Pop Hits" : 211,
"Pop Total" : 13528,
"Fold Enrichment" : 2.816712606,
"Bonferroni" : 0.152104498,
"Benjamini" : 0.002010146,
"FDR" : 0.103213309
},
{
"Cluster" : 9,
"name" : "GO:0001944~vasculature development",
"Term 1" : "GO:0001944",
"Term 2" : "vasculature development",
"size" : 23,
"%" : 3.931623932,
"PValue" : 8.15E-5,
"imports" : [ 5747, 1464, 857, 285, 10512, 51330, 3676, 3685, 83605, 3491, 7052, 10630, 8828, 7424, 1490, 7852, 3553, 4691, 9474, 4323, 7057, 5328, 3576 ],
"List Total" : 478,
"Pop Hits" : 251,
"Pop Total" : 13528,
"Fold Enrichment" : 2.593342113,
"Bonferroni" : 0.208028334,
"Benjamini" : 0.002646828,
"FDR" : 0.145864099
},
{
"Cluster" : 9,
"name" : "GO:0001568~blood vessel development",
"Term 1" : "GO:0001568",
"Term 2" : "blood vessel development",
"size" : 22,
"%" : 3.760683761,
"PValue" : 1.61E-4,
"imports" : [ 5747, 1464, 857, 285, 10512, 51330, 3676, 3685, 83605, 3491, 7052, 8828, 7424, 1490, 7852, 3553, 4691, 9474, 4323, 7057, 5328, 3576 ],
"List Total" : 478,
"Pop Hits" : 245,
"Pop Total" : 13528,
"Fold Enrichment" : 2.541337204,
"Bonferroni" : 0.370044698,
"Benjamini" : 0.004610403,
"FDR" : 0.288798997
},
{
"Cluster" : 9,
"name" : "GO:0001525~angiogenesis",
"Term 1" : "GO:0001525",
"Term 2" : "angiogenesis",
"size" : 15,
"%" : 2.564102564,
"PValue" : 7.44E-4,
"imports" : [ 5747, 1464, 285, 51330, 3491, 8828, 7424, 1490, 7852, 3553, 4691, 4323, 7057, 3576, 5328 ],
"List Total" : 478,
"Pop Hits" : 148,
"Pop Total" : 13528,
"Fold Enrichment" : 2.868370463,
"Bonferroni" : 0.881164657,
"Benjamini" : 0.01565408,
"FDR" : 1.324258979
},
{
"Cluster" : 10,
"name" : "GO:0050727~regulation of inflammatory response",
"Term 1" : "GO:0050727",
"Term 2" : "regulation of inflammatory response",
"size" : 15,
"%" : 2.564102564,
"PValue" : 3.51E-7,
"imports" : [ 2167, 6288, 5743, 5008, 313, 3620, 80381, 6352, 7052, 9180, 50604, 2207, 4907, 3559, 100 ],
"List Total" : 478,
"Pop Hits" : 76,
"Pop Total" : 13528,
"Fold Enrichment" : 5.585774059,
"Bonferroni" : 0.001005119,
"Benjamini" : 3.24E-5,
"FDR" : 6.29E-4
},
{
"Cluster" : 10,
"name" : "GO:0048585~negative regulation of response to stimulus",
"Term 1" : "GO:0048585",
"Term 2" : "negative regulation of response to stimulus",
"size" : 15,
"%" : 2.564102564,
"PValue" : 1.04E-5,
"imports" : [ 6288, 313, 26585, 80381, 7040, 6696, 3667, 3553, 9021, 4907, 3559, 5788, 3575, 100, 1493 ],
"List Total" : 478,
"Pop Hits" : 100,
"Pop Total" : 13528,
"Fold Enrichment" : 4.245188285,
"Bonferroni" : 0.02937654,
"Benjamini" : 4.38E-4,
"FDR" : 0.018659509
},
{
"Cluster" : 10,
"name" : "GO:0032102~negative regulation of response to external stimulus",
"Term 1" : "GO:0032102",
"Term 2" : "negative regulation of response to external stimulus",
"size" : 8,
"%" : 1.367521368,
"PValue" : 0.00174166,
"imports" : [ 6288, 6696, 313, 4907, 26585, 3559, 100, 80381 ],
"List Total" : 478,
"Pop Hits" : 50,
"Pop Total" : 13528,
"Fold Enrichment" : 4.528200837,
"Bonferroni" : 0.99318737,
"Benjamini" : 0.029962542,
"FDR" : 3.074188039
},
{
"Cluster" : 10,
"name" : "GO:0050728~negative regulation of inflammatory response",
"Term 1" : "GO:0050728",
"Term 2" : "negative regulation of inflammatory response",
"size" : 6,
"%" : 1.025641026,
"PValue" : 0.004246869,
"imports" : [ 6288, 313, 4907, 3559, 100, 80381 ],
"List Total" : 478,
"Pop Hits" : 31,
"Pop Total" : 13528,
"Fold Enrichment" : 5.477662303,
"Bonferroni" : 0.99999487,
"Benjamini" : 0.059663312,
"FDR" : 7.339986737
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{
"Cluster" : 10,
"name" : "GO:0031348~negative regulation of defense response",
"Term 1" : "GO:0031348",
"Term 2" : "negative regulation of defense response",
"size" : 6,
"%" : 1.025641026,
"PValue" : 0.008159522,
"imports" : [ 6288, 313, 4907, 3559, 100, 80381 ],
"List Total" : 478,
"Pop Hits" : 36,
"Pop Total" : 13528,
"Fold Enrichment" : 4.716875872,
"Bonferroni" : 1,
"Benjamini" : 0.095738493,
"FDR" : 13.64947492
}
]
Raw
index.html
<!DOCTYPE html>
<meta charset="utf-8">
<style>
.node {
font: 10px sans-serif;
}
.link {
stroke: steelblue;
stroke-opacity: .4;
fill: none;
}
</style>
<body>
<script src="http://d3js.org/d3.v3.min.js"></script>
<script>
var diameter = 960,
radius = diameter / 2,
innerRadius = radius - 120;
var cluster = d3.layout.cluster()
.size([360, innerRadius])
.sort(null)
.value(function(d) { return d.size; });
var bundle = d3.layout.bundle();
var line = d3.svg.line.radial()
.interpolate("bundle")
.tension(.85)
.radius(function(d) { return d.y; })
.angle(function(d) { return d.x / 180 * Math.PI; });
var svg = d3.select("body").append("svg")
.attr("width", diameter)
.attr("height", diameter)
.append("g")
.attr("transform", "translate(" + radius + "," + radius + ")");
d3.json("human_up_10.json", function(error, classes) {
var nodes = cluster.nodes(packages.root(classes)),
links = packages.imports(nodes);
svg.selectAll(".link")
.data(bundle(links))
.enter().append("path")
.attr("class", "link")
.attr("d", line);
svg.selectAll(".node")
.data(nodes.filter(function(n) { return !n.children; }))
.enter().append("g")
.attr("class", "node")
.attr("transform", function(d) { return "rotate(" + (d.x - 90) + ")translate(" + d.y + ")"; })
.append("text")
.attr("dx", function(d) { return d.x < 180 ? 8 : -8; })
.attr("dy", ".31em")
.attr("text-anchor", function(d) { return d.x < 180 ? "start" : "end"; })
.attr("transform", function(d) { return d.x < 180 ? null : "rotate(180)"; })
.text(function(d) { return d.key; });
});
d3.select(self.frameElement).style("height", diameter + "px");
var packages = {
// Lazily construct the package hierarchy from class names.
root: function(classes) {
var map = {};
function find(name, data) {
var node = map[name], i;
if (!node) {
node = map[name] = data || {name: name, children: []};
if (name.length) {
node.parent = find(name.substring(0, i = name.lastIndexOf(".")));
node.parent.children.push(node);
node.key = name.substring(i + 1);
}
}
return node;
}
classes.forEach(function(d) {
find(d.name, d);
});
return map[""];
},
// Return a list of imports for the given array of nodes.
imports: function(nodes) {
var map = {},
imports = [];
// Compute a map from name to node.
nodes.forEach(function(d) {
map[d.name] = d;
});
// For each import, construct a link from the source to target node.
nodes.forEach(function(d) {
if (d.imports) d.imports.forEach(function(i) {
imports.push({source: map[d.name], target: map[i]});
});
});
return imports;
}
};
</script>
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