WSProxy-Create_DE.js

 <script runat=server>
Platform.Load("core","1.1.5");
var prox = new Script.Util.WSProxy();

var guid = Platform.Function.GUID();
var name = "my test de - " + guid;

var de = {
    Name: name,
    CustomerKey: guid,
    Description: "Another DE added via SSJS",
    Fields: [{
        FieldType: "Text",
        Name: "ID",
        MaxLength: 36,
        IsPrimaryKey: true,
        IsNillable: false,
        IsRequired: true
    },
    {
        FieldType: "Text",
        Name: "Name",
        MaxLength: 200
    }],
    CategoryID: 1909
}

var res = prox.createItem("DataExtension", de);
</script>