Snippet that initializes a DB with all the tables defined in a peewee ORM model... in this case "MariaModel". Add tables to the model at any point and the program should be able to set up the DB programmatically.

ModelDB.py

for t in [ name for name,c in \
               inspect.getmembers(sys.modules[__name__],inspect.isclass) \
               if issubclass(c, MariaModel) and not c is MariaModel]:
    try:
        globals()[t].create_table()
    except Exception as e:
        print e

Only downside is that it doesn't ensure hierarchical creation of the tables and therefore foreign key enforcement.